Dear Reader,

As we approach the end of 2016, and publish our final issue of Drug Safety for the year, I wish to reflect on another successful year for the journal and for others in the Adis Premier journals portfolio, and to thank all who have contributed to Drug Safety over the past 12 months.

Drug Safety is now in its 30th year of publication with a current 2015 Impact Factor of 3.206 (an increase of 13.5% on 2014). As I write this letter at the end of October, the following 15 articles have already been downloaded over 1000 times this year.Footnote 1

  • Causes of Medication Administration Errors in Hospitals: a Systematic Review of Quantitative and Qualitative Evidence. Richard N. Keers, Steven D. Williams, Jonathan Cooke, Darren M. Ashcroft [http://link.springer.com/article/10.1007/s40264-013-0090-2]

  • Current Safety Concerns with Human Papillomavirus Vaccine: A Cluster Analysis of Reports in VigiBase®. Rebecca E. Chandler, Kristina Juhlin, Jonas Fransson, Ola Caster, I. Ralph Edwards, G. Niklas Norén [http://link.springer.com/article/10.1007/s40264-016-0456-3]

  • Transplantation for Acute Liver Failure in Patients Exposed to NSAIDs or Paracetamol (Acetaminophen): The Multinational Case-Population SALT Study. Sinem Ezgi Gulmez, Dominique Larrey, Georges-Philippe Pageaux, Severine Lignot, Régis Lassalle, Jérémy Jové, Angelo Gatta, P. Aiden McCormick, Harold J. Metselaar, Estela Monteiro, Douglas Thorburn, William Bernal, Irene Zouboulis-Vafiadis, Corinne de Vries, Susana Perez-Gutthann, Miriam Sturkenboom, Jacques Bénichou, Jean-Louis Montastruc, Yves Horsmans, Francesco Salvo, Fatima Hamoud, Sophie Micon, Cécile Droz-Perroteau, Patrick Blin, Nicholas Moore. [http://link.springer.com/article/10.1007/s40264-012-0013-7]

  • Good Signal Detection Practices: Evidence from IMI PROTECT. Antoni F. Z. Wisniewski, Andrew Bate, Cedric Bousquet, Andreas Brueckner, Gianmario Candore, Kristina Juhlin, Miguel A. Macia-Martinez, Katrin Manlik, Naashika Quarcoo, Suzie Seabroke, Jim Slattery, Harry Southworth, Bharat Thakrar, Phil Tregunno, Lionel Van Holle, Michael Kayser, G. Niklas Norén [http://link.springer.com/article/10.1007/s40264-016-0405-1]

  • Pharmacokinetics, Efficacy, and Safety of Hepatitis C Virus Drugs in Patients with Liver and/or Renal Impairment. Elise J. Smolders, Clara T. M. M. de Kanter, Bart van Hoek, Joop E. Arends, Joost P. H. Drenth, David M. Burger [http://link.springer.com/article/10.1007/s40264-016-0420-2]

  • An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval. Tal Lorberbaum, Kevin J. Sampson, Raymond L. Woosley, Robert S. Kass, Nicholas P. Tatonetti [http://link.springer.com/article/10.1007/s40264-016-0393-1]

  • Digital Drug Safety Surveillance: Monitoring Pharmaceutical Products in Twitter . Clark C. Freifeld, John S. Brownstein, Christopher M. Menone, Wenjie Bao, Ross Filice, Taha Kass-Hout, Nabarun Dasgupta [http://link.springer.com/article/10.1007/s40264-014-0155-x]

  • Social Media Mining for Toxicovigilance: Automatic Monitoring of Prescription Medication Abuse from Twitter. Abeed Sarker, Karen O’Connor, Rachel Ginn, Matthew Scotch, Karen Smith, Dan Malone, Graciela Gonzalez [http://link.springer.com/article/10.1007/s40264-015-0379-4]

  • Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors. Henning Blume, Frank Donath, André Warnke, Barbara S. Schug [http://link.springer.com/article/10.2165/00002018-200629090-00002]

  • Pregnancy Outcomes in the Tofacitinib Safety Databases for Rheumatoid Arthritis and Psoriasis. Megan E. B. Clowse, Steven R. Feldman, John D. Isaacs, Alexandra B. Kimball, Vibeke Strand, Richard B. Warren, Daniel Xibillé, Yan Chen, Donald Frazier, Jamie Geier, James Proulx, Amy Marren [http://link.springer.com/article/10.1007/s40264-016-0431-z]

  • Individual NSAIDs and Upper Gastrointestinal Complications: A Systematic Review and Meta-Analysis of Observational Studies (the SOS Project). Jordi Castellsague, Nuria Riera-Guardia, Brian Calingaert, Cristina Varas-Lorenzo, Annie Fourrier-Reglat, Federica Nicotra, Miriam Sturkenboom, Susana Perez-Gutthann, Safety of Non-Steroidal Anti-Inflammatory Drugs (SOS) Project [http://link.springer.com/article/10.1007/BF03261999]

  • The Patient’s Voice in Pharmacovigilance: Pragmatic Approaches to Building a Patient-Centric Drug Safety Organization. Meredith Y. Smith, Isma Benattia [http://link.springer.com/article/10.1007/s40264-016-0426-9]

  • Social Media Listening for Routine Post-Marketing Safety Surveillance . Gregory E. Powell, Harry A. Seifert, Tjark Reblin, Phil J. Burstein, James Blowers, J. Alan Menius, Jeffery L. Painter, Michele Thomas, Carrie E. Pierce, Harold W. Rodriguez, John S. Brownstein, Clark C. Freifeld, Heidi G. Bell, Nabarun Dasgupta [http://link.springer.com/article/10.1007/s40264-015-0385-6]

  • The Impact of Experiencing Adverse Drug Reactions on the Patient’s Quality of Life: A Retrospective Cross-Sectional Study in the Netherlands. Leàn Rolfes, Florence van Hunsel, Katja Taxis, Eugène van Puijenbroek [http://link.springer.com/article/10.1007/s40264-016-0422-0]

  • Benefit–Risk Assessment of Fish Oil in Preventing Cardiovascular Disease. Bill Lands [http://link.springer.com/article/10.1007/s40264-016-0438-5]

The majority of our other journals saw a rise in impact factor against the previous year. Most notably, four of our other journals also saw an increase of over 10% in impact factor—The Patient (17.08%), Clinical Drug Investigation (15.99%), the American Journal of Clinical Dermatology (13.17% increase) and Drugs (12.43%).

Another important milestone was reached for our recently launched open access journals, Drug Safety—Case Reports and Drugs—Real World Outcomes. Content from these journals is now available on PubMed Central.

The Adis journals portfolio will expand in 2017, with the launch of PharmacoEconomics—Open. This new journal will be fully open access and will focus on the publication of applied research on the economic implications and health outcomes associated with drugs, devices and other healthcare interventions. It joins our other well respected health outcomes publications, PharmacoEconomics, Applied Health Economics and Health Policy and, The Patient: Patient-Centered Outcomes Research.

I offer my sincere thanks to all authors who have contributed articles to Drug Safety over the course of 2016. Their skill and dedication are critical to the continued publication of the journal. The quality of published articles is, similarly, testament to the significant efforts of the peer reviewers, whose commitment ensures that the journal’s content is held to the highest possible standard. I would like to thank the following individuals who acted as reviewers for Drug Safety in the last 12 months:

Ivo Abraham, USA

Tom Achoki, USA

Anurag K. Agrawal, USA

Alexandra Alexopoulou, Greece

Karel Allegaert, Belgium

Morten Andersen, Sweden

Daniel Antoine, UK

Peter Arlett, UK

Mickael Arnaud, France

Donald Arnold, Canada

Parisa Aslani, Australia

Elizabeth Asztalos, USA

Mark Avigan, USA

David J. Back, UK

J.M. Baeten, USA

Marian K. Bakker, The Netherlands

Juan M. Banda, USA

Anjan Banerjee, UK

Kátia P. Barreto, Brazil

Andrew Bate, UK

Brian Bateman, USA

Vincent G. Bauchau, Belgium

Bernard Begaud, France

Joseph R. Berger, USA

Miles Berger, USA

Jesse Berlin, USA

Delphine Bertram, France

Maarten J. Bijlsma, The Netherlands

Einar S. Björnsson, Sweden

Susan J. Blalock, USA

Corrado Blandizzi, Italy

Patrick Blin, France

John J. Borg, Malta

Ian W. Boyd, Australia

M. Alan Brookhart, USA

Katsiaryna Bykov, USA

Davide Caimmi, France

D.M. Carpenter, USA

Alfonso Carvajal, Spain

Ola Caster, Sweden

Luigi Celio, Italy

Eliza Chakravarty, USA

Shilin Chen, China

Ching-Chi Chi, Taiwan

Imti Choonara, UK

Hannah Christensen, UK

David B. Clifford, USA

Hazel J. Clothier, Australia

Megan Coghlan, Australia

Preciosa M. Coloma, Switzerland

Anita Conforti, Italy

Mario D. Cordero, Spain

Sabrina Crepin, France

Simon Croft, UK

Gerald Dal Pan, USA

Christine Damase-Michel, France

Gaby Danan, France

Gregory W. Daniel, USA

Borje Darpo, Sweden

Nabarun Dasgupta, USA

Hugo J. de Boer, Sweden

Fabrizio De Ponti, Italy

Peter A. De Smet, The Netherlands

Sieta T. de Vries, The Netherlands

James P. Dillard, USA

Roni P. Dodiuk-Gad, Israel

Brian D. Edwards, UK

Vanessa Elharrar, USA

Moses S.,Elisaf, Greece

Deshayne B. Fell, Canada

Georg Ferber, Switzerland

Carmen Ferrajolo, Italy

Daniel Fife, USA

Albert Figueras, Spain

Rebecca Fischer-Betz, Germany

Robert J. Fontana, USA

Robert J. Fox, USA

Anthony W. Fox, UK

Nicolas Franchitto, France

Bryony D. Franklin, UK

Gerrit Frommeyer, Germany

John-Michael Gamble, Canada

Keming Gao, USA

Luis A. García-Rodríguez, Spain

Johnson George, Australia

David Gerrett, UK

Thijs J. Giezen, The Netherlands

Christophe Giraud-Carrier, USA

Wendy Gold, Australia

Graciela Gonzalez, USA

Claus Graff, Denmark

Luke Grzeskowiak, Australia

Katja M. Hakkarainen, Sweden

Sebastian Harder, Germany

Rave Harpaz, USA

Katherine E. Hartmann, USA

Abraham Hartzema, USA

Manfred Hauben, USA

Lutz Heide, Germany

Raquel Herrera Comoglio, Argentina

Maria Herrero-Zazo, UK

Richard Hill, Australia

James M. Hoffman, USA

Marie C. Hogan, USA

Bruce Holub, Canada

Jay H. Hoofnagle, USA

Weng-Foung Huang, Taiwan

Richard B. Hubbard, UK

Bruce P.J. Hugman, Thailand

Katarina Ilic, USA

Shinobu Imai, Japan

Patrick Imfeld, Switzerland

Ambrose O. Isah, Nigeria

Vincent Jacquemet, Canada

Narumol Jarernsiripornkul, Thailand

Catherine B. Johannes, USA

Juergen John, Germany

Michele Jonsson-Funk, USA

Bengt Kallen, Sweden

Jason H. Karnes, USA

Chinmayee Katragadda, USA

Philip O. Katz, USA

Richard N. Keers, UK

Theodoros Kelesidis, USA

Peter Kim, USA

Jennifer J. Kiser, USA

Peter Knapp, UK

Caitlin A. Knox, USA

Ryuji Koike, Japan

Ross Koppel, USA

Jan A. Kors, The Netherlands

Vassilis Koutkias, Greece

Helena C. Kraemer, USA

Martin M. Kulldorff, USA

Craig Lammert, USA

Pierantonio Laveneziana, France

Willem F. Lems, The Netherlands

Roberto Leone, Italy

Katherine J. Lepik, Canada

Lang Li, USA

Vincent Lo Re, USA

Pier L. Lopalco, Sweden

Malcolm Maclure, Canada

Francois Maignen, UK

Eugene O. Major, USA

Marek Malik, UK

Elizabeth Manias, Australia

John McEwen, Australia

Ushma Mehta, South Africa

Christian Meier, Switzerland

Joelle Micallef, France

Cyrus D. Mintz, USA

Thomas J. Moore, USA

Ugo Moretti, Italy

Kirsten Morley, Australia

Alessandro Mugelli, Italy

Paul N. Newton, UK

G. Niklas Noren, Sweden

Jeremy P. Nuttall, USA

Sten Olsson, Sweden

Ian Olver, Australia

Daniel Ontaneda, USA

Vicki Osborne, USA

Alexandra C. Pacurariu, The Netherlands

Clive Page, UK

Shanthi Pal, Switzerland

Akhil Parashar, USA

Antoine Pariente, France

Nimish Patel, USA

Rupert A. Payne, UK

Federico Pea, Italy

Robert W. Platt, Canada

Vitali Pool, USA

Robin J. Prescott, UK

Richard W. Price, USA

Dennis W. Raisch, USA

Emmae Ramsay, Australia

Emanuel Raschi, Italy

Jenna M. Reps, UK

Winfried Rief, Germany

Bianca Rocca, Italy

Jürgen K. Rockstroh, Germany

Tiago Rodrigues, Brazil

Leàn Rolfes, The Netherlands

Susan L. Rosenkranz, USA

Elizabeth Roughead, Australia

Jean-Claude Roujeau, France

Gerta Rücker, Germany

Yoshinobu Saito, Japan

Francesco Salvo, France

Stefan Sauerland, Germany

Carmelo Scarpignato, Italy

Nikolai M. Scheller, Denmark

Guntram Schernthaner, Austria

Jonathan S. Schildcrout, USA

Suzie Seabroke, UK

John D. Seeger, USA

Jodi B. Segal, USA

John R. Senior, USA

Stephen Senn, Luxembourg

Esperança Sevene, Mozambique

Tom T. Shimabukuro, USA

Ming-Neng Shiu, Taiwan

Matthew A. Silva, USA

Andrew Sinclair, Australia

Barbara Sinner, Germany

Gunilla Sjölin-Forsberg, Switzerland

Helena Sköld, Sweden

Adrian Slater, UK

Jim Slattery, UK

Meredith Y. Smith, USA

Edoardo Spina, Italy

Brock Stewart, USA

Michael A. Stoto, USA

Aaron K. Styer, USA

Alex Sundermann, USA

Ana Szarfman, USA

Stanley J. Szefler, USA

Yoshinori Takeuchi, Japan

Juan Tamargo, Spain

Udaya S. Tantry, USA

Michael V. Tatley, New Zealand

Katja Taxis, The Netherlands

Sarah N. Taylor, USA

Rolf Teschke, Germany

Michael D. Thorn, USA

Henrik Toft Sørensen, Denmark

Sengwee Toh, USA

Ludovic Trinquart, USA

Pascale Tubert-Bitter, France

Paul M. Tulkens, Belgium

Marinka Twilt, Canada

Andre van der Ven, The Netherlands

A.C. van Grootheest, The Netherlands

Florence van Hunsel, The Netherlands

Frederick Varricchio, USA

Mauro Venegoni, Italy

Niels Vermeer, The Netherlands

Ermelinda Viola, Italy

Gianni Virgili, Italy

Jiri Vlcek, Czech Republic

Rüdiger von Kries, Germany

Paul B. Watkins, USA

Rainer Winnenburg, USA

Almut G. Winterstein, USA

Gaetano Zaccara, Italy

Mauro Zaccarelli, Italy

Rui Zhang, USA

In addition, I would like to thank the members of the journal’s Honorary Editorial Board, who have acted as peer reviewers and authors, and have provided guidance on journal content, policy and processes:

G. Caleb Alexander, USA

Bernard Bannwarth, France

Joanne Barnes, New Zealand

David W. Bates, USA

Jean-François Bergmann, France

Frank M.C. Besag, UK

Elliot G. Brown, UK

Nick Buckley, Australia

Ric Day, Australia

Alexander N.O. Dodoo, Ghana

I. Ralph Edwards, Sweden

A.C.G. (Toine) Egberts, The Netherlands

Stephen J.W. Evans, UK

Adolfo Figueiras, Spain

Joshua Gagne, USA

Stephen A. Goldman, USA

Arnold J. Gordon, USA

Staffan Hägg, Sweden

Kenneth Hartigan-Go, Philippines

Laurie Howes, Australia

Susan Jick, USA

Stephan Krähenbühl, Switzerland

Kiyoshi Kubota, Japan

Joan-Ramon Laporte, Spain

Deborah Layton, UK

Marie Lindquist, Sweden

Yoon K. Loke, UK

Christoph R. Meier, Switzerland

Ronald Meijboom, The Netherlands

Peter G.M. Mol, The Netherlands

Jean-Louis Montastruc, France

Nicholas Moore, France

G. Niklas Norén, Sweden

Munir Pirmohamed, UK

Ruth Savage, New Zealand

Nigam Shah, USA

Rashimi R. Shah, UK

Saad Shakir, UK

Neil Shear, Canada

Olav Spigset, Norway

Nicholas P. Tatonetti, USA

Gianluca Trifirò, Italy

Marco Tuccori, Italy

Eugene P. van Puijenbroek, The Netherlands

Lynda V. Wilton, UK

Ian C.K. Wong, UK

I hope that you have found the articles published throughout 2016 to be both interesting and informative. I have appreciated the high quality of content contributed to the journal this year and I look forward to keeping you up to date with topical issues in pharmacovigilance and pharmacoepidemiology in 2017.

With best wishes

Nitin Joshi

Editor, Drug Safety