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Fig. 8 | Clinical Pharmacokinetics

Fig. 8

From: Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059

Fig. 8

Simulation of inotuzumab ozogamicin (InO) in adult and pediatric patients with B-cell precursor acute lymphoblastic leukemia (ALL). a Simulated concentration–time profile for four cycles. Green lines denote InO exposure in pediatric patients and red lines denote InO exposure in adults. Medians are shown with dashed lines, the 10th and 90th percentiles are shown with solid lines. b Cumulative area under the concentration–time curve (AUC) at the end of each cycle

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