Pharmaceutical Costs of Assisted Reproduction in Spain
- 74 Downloads
Assisted reproduction is one of the health services currently being considered for possible limitation or exclusion from the public health services portfolio in Spain. One of the main reasons claimed for this is the impact on the budget for pharmaceutical expenditure.
The objective of this study was to assess the significance of the pharmaceutical costs of assisted reproduction in Spain.
This study focused on medical practice in Spain, and is based on the opinions of experts in assisted reproduction and the results provided by professional societies’ publications. The reference year is 2012 and the setting was secondary care. We have included all existing pharmaceutical modalities for assisted reproduction, as well as the most common drug for each modality. We have considered the pharmaceutical cost per cycle for artificial insemination, in vitro fertilisation with or without intracytoplasmic sperm injection (IVF_ICSI), and cryotransfer and donated fresh oocytes reception.
In Spain, artificial insemination has a pharmaceutical cost per cycle of between €69.36 and €873.79. This amounts to an average cycle cost of €364.87 for partner’s sperm and €327.10 for donor sperm. The pharmaceutical cost of IVF_ICSI ranges between €278.16 and €1,902.66, giving an average cost per cycle of €1,139.65. In the case of cryotransfer and donated fresh oocytes reception, the pharmaceutical cost per cycle is between €22.61 and €58.73, yielding an average cost of €40.67. The budgetary impact of pharmaceutical expenditure for assisted reproduction in Spain for the year 2012 was estimated at €98.7 million.
In Spain, the total pharmaceutical cost of assisted reproduction is substantial. According to our results, we can say that about 29 % of the total pharmaceutical expenditure for assisted reproduction techniques is funded by the National Health System and the rest represents 2.4 % of the total annual out-of-pocket family expenditure on drugs.
KeywordsAverage Cost Ovarian Stimulation Artificial Insemination Assisted Reproduction Budgetary Impact
No sources of funding were used to assist in the preparation of this study. The authors have no potential conflicts of interest that are directly relevant to the content of this study.
- 1.National Institute of Statistics in Spain. Natural movement of the population, by 2011. Births definitive. http://www.ine.es/. Accessed 18 Jan 2013.
- 2.Agramunt S, Czech MA, Carreras R. Reproductive treatment efficacy. In: Matorras R, editor. Infertility in Spain: current situation and prospects [in Spanish]. Madrid: Imago Concept & Image Development; 2011. p. 123–34.Google Scholar
- 3.Prados F, de los Santos MJ, Cabello Y, et al. Registro de la Sociedad Española de Fertilidad: Técnicas de reproducción asistida (IA y FIV/ICSI). Año 2010. http://www.registrosef.com. Accessed 21 Dec 2012.
- 6.Balasch J, Barri PN. Thoughts on the cost-effectiveness of recombinant FSH for assisted fertilization. Clinical standpoint [in Spanish]. Rev Iberoam Fertil Reprod Hum. 2000;17(5):11–20.Google Scholar
- 7.Slof J. Cost comparison of controlled ovarian stimulation with rFSH-alfa and rFSH-beta using a pen-device [in Spanish]. Rev Iberoam Fertil Reprod Hum. 2010;27(5):399–411.Google Scholar
- 8.Matorras R, Valladolid A, Rodriguez-Escudero FJ. The cost of assisted reproduction techniques in the public health system: the Cruces Hospital experience [in Spanish]. Rev Iberoam Fertil Reprod Hum. 2001;18(3):146–50.Google Scholar
- 9.Association for Social, Economics and Civil Rights (ADECES). Técnicas de reproducción asistida: La necesidad de ampliar la atención. Año 2011. http://www.adeces.org/. Accessed 1 Jan 2013.
- 10.Ruiz-Balda JA, López JM, Prieto L. Cost-effectiveness study of assisted reproduction techniques in Spain [in Spanish]. Rev Esp Econ Salud. 2005;4(2):96–102.Google Scholar
- 12.Vademecum. http://www.vademecum.es/. Accessed 23 Dec 2012.
- 13.Pharmaceutical General Council. Database price database of medicines and health products. http://www.portalfarma.com/. Accessed 27 Dec 2012.
- 14.National Institute of Statistics in Spain. National Survey of Family Budgets in 2011. http://www.ine.es/. Accessed 15 Jul 2013.