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Chemical Research in Chinese Universities

, Volume 35, Issue 5, pp 775–781 | Cite as

Chemiluminescence Determination of Cefixime Trihydride Based on Acidic Diperiodatoargentate(III)-Rhodamine 6-G System

  • Yousaf Muhammad
  • Yaqoob MohammedEmail author
  • Asghar Muhammad
  • Ali Samar
Article
  • 14 Downloads

Abstract

A novel chemiluminescence(CL) method is proposed for cefixime trihydride(CFX) determination based on its enhancement effect on diperiodatoargentate(III)(DPA)-rhodamine 6-G(Rh6-G) reaction in conjunction with flow injection analysis(FIA). A linear calibration curve was achieved over the range from 0.01 mg/L to 2.5 mg/L CFX(R2=0.999, n=8) with relative standard deviation(RSD) of 1.4%—3.8%(n=4)), limit of detection(LOD) of 3.0×10–3 mg/L(S/N=3), injection throughput of 180/h and regression equation of y=1113.2x–14.596[y=CL intensity (mV) and x=concentration of CFX(mg/L)]. The method was successfully applied to CFX determination in pharmaceutical formulations and the recoveries(%) for proposed FI-CL and a reported spectrophotometric method by applying the Student t-test [calculated t-test value: t=1.079215, and tabulated t-distributed(95%)=2.200985] were not significantly different. The CFX was efficiently extracted and no significant effect of commonly found excipients in the pharmaceutical formulations was observed. The mechanism of CL reaction is discussed briefly.

Keywords

Cefixime trihydride Diperiodatoargentate(III) Rhodamine 6-G Chemiluminescence Flow injection analysis Pharmaceutical formulation 

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Notes

Acknowledgments

The authors acknowledge Nexus Pharma(Pvt.) Limited, Karachi, Pakistan for providing pure cefixime trihydrate as a gift.

References

  1. [1]
    Kalyani J. V., Rastogi R. B., Kumar D., RSC Adv., 2014, 4, 30500CrossRefGoogle Scholar
  2. [2]
    Dubala A., Nagarajan J. S. K., Vimal C. S., George R., J. Chromatogr. Sci., 2014, 53, 694CrossRefGoogle Scholar
  3. [3]
    Wani Y. B., Patil D. D., J. Saudi. Chem. Soc., 2017, 21, S101CrossRefGoogle Scholar
  4. [4]
    Karimian N., Gholivand M. B., Malekzadeh G., J. Electroanal. Chem., 2016, 771, 64CrossRefGoogle Scholar
  5. [5]
    Troy D. B., Beringer P., Remingtons, The Science and Practice of Pharmacy, 21st Ed., Vol. II, 2005, 1644Google Scholar
  6. [6]
    Katzung B., Basic and Clinical Pharmacology(10th Ed.), McGraw-Hill Medical, Charlottesville, 2006, 726Google Scholar
  7. [7]
    Nagaraju K., Chowdary Y. A., Int. J. Sci. Res. Sci. Tech., 2018, 4, 669Google Scholar
  8. [8]
    Chowdary A. H., Kiranjyothi R., Priyanka J., Int. J. Pharm. Biol. Sci. Arch., 2018, 6, 19Google Scholar
  9. [9]
    Hassouna M. E. M., Abdelrahman M. M., Mohamed M. A., J. Foren-sic. Sci., 2017, 2, 1Google Scholar
  10. [10]
    Memon N. A., Memon A. A., Memon F. N., Sherazi S. T. H., Memon S., Leghari M. K., Chromatographia, 2018, 81, 1373CrossRefGoogle Scholar
  11. [11]
    Maheshwari M. L., Memon A. A., Memon S., Mughal U. U. R., Dayo A., Memon N., Ghoto M. A., Leghari M. K., Saudi Pharm. J., 2015, 23, 444CrossRefGoogle Scholar
  12. [12]
    Kundu S., Majumder T., Barat P. K., Ray S. K., Int. J. Pharm. Sci. Res., 2015, 6, 884Google Scholar
  13. [13]
    Dehghani M., Nasirizadeh N., Yazdanshenas M. E., Mater. Sci. Eng., 2019, 96, 654CrossRefGoogle Scholar
  14. [14]
    Balooei M., Raoof J. B., Chekin F., Ojani R., Anal. Bioanal. Elec-trochem., 2017, 9, 266Google Scholar
  15. [15]
    Yaman Y. T., Bolat G., Yardimci C., Abaci S., Turk. J. Chem., 2018, 42, 826Google Scholar
  16. [16]
    Norouzi B., Tajjedin S., Bulg. Chem. Commun., 2017, 49, 729Google Scholar
  17. [17]
    Fakhri A., Shahidi S., Agarwal S., Gupta V. K., Int. J. Electrochem. Sci., 2016, 11, 1530Google Scholar
  18. [18]
    Eskandari H., Amirzehni M., Asadollahzadeh H., Hassanzadeh J., Eslami P. A., Sensor. Actuat. B: Chem., 2018, 275, 145CrossRefGoogle Scholar
  19. [19]
    Pan H., Wang S., Dao X., Ni Y., Inorg. Chem., 2018, 57, 1417CrossRefGoogle Scholar
  20. [20]
    Akhgari F., Samadi N., Farhadi K., J. Fluoresc., 2017, 27, 921CrossRefGoogle Scholar
  21. [21]
    Eskandari H., Amirzehni M., Asadollahzadeh H., Eslami P. A., New J. Chem., 2017, 41, 7186CrossRefGoogle Scholar
  22. [22]
    Gandhi S. V., Sonawane P. S., Asian J. Res. Chem., 2018, 11, 705CrossRefGoogle Scholar
  23. [23]
    Amraei A., Niazi A., Iran. J. Pharm. Res., 2018, 17, 1191PubMedPubMedCentralGoogle Scholar
  24. [24]
    Masoudyfar Z., Elhami S., Spectrochim. Acta A, 2019, 211, 234CrossRefGoogle Scholar
  25. [25]
    Khan M. N., Qayum A., Rehman U. U., Gulab H., Idrees M., J. Appl. Spectrosc., 2015, 82, 705CrossRefGoogle Scholar
  26. [26]
    Keskar M. R., Jugade R. M., Anal. Chem. Insights, 2015, 10, ACI–S28463Google Scholar
  27. [27]
    Fletcher P., Andrew K. N., Calokerinos A. C., Forbes S., Worsfold, P. J., Luminescence, 2001, 16, 1CrossRefGoogle Scholar
  28. [28]
    Li B., Zhang Z., Wu M., Talanta, 2000, 51, 515CrossRefGoogle Scholar
  29. [29]
    Yue L., Chem. Res. Chinese Universities, 2018, 34(5), 758CrossRefGoogle Scholar
  30. [30]
    Balikungeri A., Pelletier M., Inorg. Chim. Acta, 1978, 29, 141CrossRefGoogle Scholar
  31. [31]
    Murthy C. P., Sethnram B., Rao T. N., Z. Phy. Chem., 1986, 267, 1212Google Scholar
  32. [32]
    Asghar M., Yaqoob M., Nabi A., Chem. Res. Chinese Universities, 2017, 33(2), 354CrossRefGoogle Scholar
  33. [33]
    Su M., Chen P., Sun H., TrAC Trends Anal. Chem., 2018, 100, 36CrossRefGoogle Scholar
  34. [34]
    Sun H., Chen P., Wang F., Wen H., Talanta, 2009, 79, 134CrossRefGoogle Scholar
  35. [35]
    Sun H., Chen P., Wang F., Spectrochim. Acta Part A, 2009, 74, 819CrossRefGoogle Scholar
  36. [36]
    Chen P., Sun H., Drug Test. Anal., 2010, 2, 24PubMedGoogle Scholar
  37. [37]
    Sun H., Chen P., Wang F., Anal. Lett., 2010, 43, 2234CrossRefGoogle Scholar
  38. [38]
    Fu Z. F., Li G. K., Hu Y. F., Chinese J. Anal. Chem., 2015, 43(9), 1322CrossRefGoogle Scholar
  39. [39]
    Sun H. W., Shi S. S., Wang J., Chen P. Y., Asian J. Chem., 2012, 24, 3865Google Scholar
  40. [40]
    Zhao F., Zhao W. H., Xiong W., Luminescence, 2013, 28, 108CrossRefGoogle Scholar
  41. [41]
    Fu Z., Li G., Hu Y., Anal. Methods, 2015, 7, 4590CrossRefGoogle Scholar
  42. [42]
    Asghar M., Yaqoob M., Nabi A., Int. J. Environ. Anal. Chem., 2017, 97, 276CrossRefGoogle Scholar
  43. [43]
    Ahmed M., Asghar M., Yaqoob M., Munawar N., Shahid F., Asad M., Nabi A., Anal. Sci., 2017, 33, 1259CrossRefGoogle Scholar
  44. [44]
    Du J., Li, H., Appl. Spectrosc., 2010, 64(10), 1154CrossRefGoogle Scholar
  45. [45]
    He S. H., He D. Y., J. Sichuan Normal University(Natural Science), 2008, 3, 350Google Scholar
  46. [46]
    Al Haddabi B., Al Lawati H. A., Suliman F. O., Talanta, 2016, 150, 399CrossRefGoogle Scholar
  47. [47]
    Cui H., Zhang Q., Myint A., Ge X., Liu L., J. Photochem. Photobiol. A: Chem., 2006, 181, 238CrossRefGoogle Scholar
  48. [48]
    Liu H., Hao Y., Ren J., He P., Fang Y., Luminescence, 2007, 22, 302CrossRefGoogle Scholar
  49. [49]
    He D., He S., Zhang Z., Anal. Lett., 2007, 40, 2935CrossRefGoogle Scholar
  50. [50]
    Kubin R. F., Fletcher A. N., J. Luminescence, 1982, 27, 455CrossRefGoogle Scholar
  51. [51]
    Inoue Y., Hamashima H., J. Biomater. Nanobiotechnol., 2012, 3, 136CrossRefGoogle Scholar

Copyright information

© Jilin University, The Editorial Department of Chemical Research in Chinese Universities and Springer-Verlag GmbH 2019

Authors and Affiliations

  • Yousaf Muhammad
    • 1
  • Yaqoob Mohammed
    • 1
    Email author
  • Asghar Muhammad
    • 1
  • Ali Samar
    • 1
  1. 1.Department of ChemistryUniversity of BalochistanQuettaPakistan

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