Chemical Research in Chinese Universities

, Volume 33, Issue 5, pp 773–778 | Cite as

Studies on the activities of electrophilic sites on benzene ring of 4-substituted anilines and their acyl compounds with multiphilicity descriptor

  • Xizhou Shen
  • Huajun He
  • Bowen Yang
  • Zhigang Zhao
  • Kaiyuan Shao
  • Wenxiang Hu
Article
  • 40 Downloads

Abstract

In this paper, the activities of electrophilic sites on benzene ring of 4-substituted anilines and their acyl compounds were studied with the quantitative indicator of multiphilicity descriptor. Four substituents were synthesized with microwave irradiation in good yields to verify the quantitative analysis data. Friedel-Crafts acylation was carried out by the microwave method for the first time.

Keywords

Quantum chemical calculation Electrophilic site Multiphilicity descriptor Benzodiazepine Electrophilic substitution reaction 

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Copyright information

© Jilin University, The Editorial Department of Chemical Research in Chinese Universities and Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • Xizhou Shen
    • 1
  • Huajun He
    • 1
    • 4
  • Bowen Yang
    • 2
  • Zhigang Zhao
    • 2
  • Kaiyuan Shao
    • 3
  • Wenxiang Hu
    • 1
    • 3
  1. 1.School of Chemical Engineering and PharmacyWuhan Institute of TechnologyWuhanP. R. China
  2. 2.College of Chemistry and Environment Protection EngineeringSouthwest University for NationalitiesChengduP. R. China
  3. 3.Jingdong Xianghu Laboratory of Beijing Excalibur SpaceMilitary Academy of Medical SciencesBeijingP. R. China
  4. 4.Food and Drugs Inspection & Testing Center of Jingning CountyJingningP. R. China

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