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A review of binge eating disorder and obesity

Übersicht zu Binge-eating und Adipositas

Summary

Binge eating disorder (BED) is a mental illness characterised by recurrent binge eating episodes in the absence of appropriate compensatory behaviours. Consequently, BED is strongly associated with obesity. The current review aims to provide an update of the most relevant aspects of BED (e.g., clinical profile, aetiology and treatment approaches), in order not only to facilitate a better understanding of the disorder and its clinical consequences, but also to identify potential targets of prevention and intervention. Patients with BED often present high comorbidity with other medical conditions and psychiatric disorders. Numerous risk factors have been associated with the development and maintenance of the disorder. Moreover, although some treatments for BED have proven to be effective in addressing different key aspects of the disorder, the rates of patients that have ever received specific treatment for BED are very low. The factors involved and how to implement effective treatments will be discussed for the purpose of addressing the eating symptomatology and comorbid obesity.

Zusammenfassung

Die Binge-eating-Störung (BES) ist eine psychische Erkrankung, die durch wiederkehrende Essanfälle und das Fehlen eines angemessenen Kompensationsverhaltens gekennzeichnet ist. In der Folge besteht eine starke Assoziation mit Adipositas. Der vorliegende Beitrag bietet eine aktuelle Übersicht zu den wichtigsten Gesichtspunkten von BES, unter anderem zu klinischem Bild, Ätiologie und Behandlungsansätzen. Ziel ist nicht nur ein besseres Verstehen der Erkrankung und ihrer klinischen Folgen, sondern auch die Identifikation potenzieller Ansatzpunkte für Prävention und Intervention. Patienten mit BES zeigen oft eine hochgradige Komorbidität mit anderen somatischen und psychischen Erkrankungen. Für zahlreiche Risikofaktoren wurde ein Zusammenhang mit der Entwicklung und Erhaltung der Störung ermittelt. Obwohl sich einige therapeutische Ansätze in Bezug auf verschiedene Kernaspekte der BES als wirksam erwiesen haben, hat nur ein sehr geringer Anteil der Patienten je eine spezifische Behandlung erhalten. Es werden Einflussfaktoren erörtert und die Frage diskutiert, wie sich wirksame Therapien umsetzen lassen, um die Esssymptomatik und komorbide Adipositas zu beeinflussen.

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Funding

The authors would like to thank CERCA Programme/Generalitat de Catalunya for institutional support. This manuscript was supported by grants from the Instituto de Salud Carlos III (ISCIII) (FIS PI14/00290 and PI17/01167), by the SLT006/17/00246 grant, funded by the Department of Health of the Generalitat de Catalunya by the call “Acció instrumental de programes de recerca orientats en l‘àmbit de la recerca i la innovació en salut”, and co-funded by FEDER funds/European Regional Development Fund (ERDF), a way to build Europe. CIBERObn and CIBERSAM are both initiatives of the ISCIII. María Lozano-Madrid is also supported by a predoctoral Grant of the Ministerio de Educación, Cultura y Deporte (FPU15/02911).

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Correspondence to Zaida Agüera or Fernando Fernández-Aranda.

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Z. Agüera, M. Lozano-Madrid, N. Mallorquí-Bagué, S. Jiménez-Murcia, J.M. Menchón and F. Fernández-Aranda declare that they have no competing interests. The founding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; nor in the decision to publish the results.

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Agüera, Z., Lozano-Madrid, M., Mallorquí-Bagué, N. et al. A review of binge eating disorder and obesity. Neuropsychiatr 35, 57–67 (2021). https://doi.org/10.1007/s40211-020-00346-w

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Keywords

  • Binge eating disorder
  • Obesity
  • Risk factors
  • Treatment
  • Prevalence

Schlüsselwörter

  • Binge-eating-Störung
  • Adipositas
  • Risikofaktoren
  • Behandlung
  • Prävalenz