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The response ranges of pulmonary function and the impact criteria of weather and industrial influence on patients with asthma living in Vladivostok

Abstract

Purpose

To determine the response of pulmonary function (PF) to the influence of environmental factors in patients with different levels of asthma control.

Materials and methods

Patients with controlled (136 people) and uncontrolled (96 people) asthma living in the conditions of monsoon climate and technogenic pollution in Vladivostok were examined. Discriminant analysis that provides the basis for dividing initial data into classes, as according to standards and expert estimates, was used to calculate ranges of PF response in asthma patients. The selection of discriminant functions with the highest values of constant and coefficient made it possible to identify the optimal quantitative ranges.

Results

Analysis of the discriminant value of Wilks’ lambda (α) has shown that the intensity of PF response to climatic and technogenic factors varies depending on level of disease control (controlled asthma – α = 0.67–0.79, uncontrolled asthma – α =0.05–0.44). The criteria and ranges of PF response also differ depending on level of disease control. In controlled asthma, PF response reflects an adaptive-compensatory dependence. The reaction to the environmental factors is rather weak; therefore, it could be detected by only more sensitive examination method (body plethysmography). In uncontrolled asthma, the response to the influence of environment quality is active and could be clearly identified by spirography.

Conclusions

The climatic and technogenic environment of Vladivostok causes strong pathogenic impact on patients with uncontrolled asthma. The effects of dust fraction 0–1 μm, deeply penetrating into respiratory organs, and day-to-day variability of wind speed, which induces weather sensitivity, are particularly adverse.

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References

  1. Heinrich J, Wichmann HE. Traffic related pollutants in Europe and their effect on allergic disease. Curr Opin Allergy Clin Immunol. 2004;4(5):341–8.

    CAS  Article  Google Scholar 

  2. Global Initiative for Asthma: Global Strategy for Asthma Management and Prevention (2018) Available online: https://ginasthma.org/wp-content/uploads/2018/03/wms-GINA-main-pocket-guide_2018-v1.0.pdf (accessed Nov 19 2018).

  3. Abe T, Tokuda Y, Ohde S, Ishimatsu S, Nakamura T, Birrer RB. The relationship of short-term air pollution and weather to ED visits for asthma in Japan. Am J Emerg Med. 2009;27(2):153–9. https://doi.org/10.1016/j.ajem.2008.01.013.

    Article  Google Scholar 

  4. Li X, Jiang Y, Yin L, Liu B, Du P, Hassan M, et al. Evaluation of the environmental epidemiologic data and methodology for the air quality standard in Beijing. Int J Biometeorol. 2017;61(9):1511–7. https://doi.org/10.1007/s00484-017-1330-4.

    Article  Google Scholar 

  5. Veremchuk LV, Yan'kova VI, Vitkina TI, Barskova LS, Golokhvast KS. The formation of atmospheric air pollution in Vladivostok and its impact on the prevalence of respiratory diseases. Sibirskij nauchnyj meditsinskij zhurnal. 2015;35(4):55–61 (in Russian).

    Google Scholar 

  6. Veremchuk LV, Yan'kova VI, Vitkina TI, Golokhvast KS, Barskova LS. Pollution of the atmosphere of an urbanized area as a systemic process of interaction of environmental factors. Zdorov'e. Meditsinskaya ehkologiya. Nauka. 2015;61(3):35–42 (in Russian).

    Google Scholar 

  7. Dotsenko EA, Krest'yaninova TY, Bobrova EP. The influence of weather and climatic conditions on the course of bronchial asthma. Problemy zdorov'ya i ehkologii. 2004;2:41–8 (in Russian).

    Google Scholar 

  8. Lai LW. Public health risks of prolonged fine particle events associated with stagnation and air quality index based on fine particlematter with a diameter <2.5 μm in the Kaoping region of Taiwan. Int J Biometeorol. 2016;60(12):1907–17. https://doi.org/10.1007/s00484-016-1177-0.

    Article  Google Scholar 

  9. D’Amato G, Holgate ST, Pawankar R, Ledford DK, Cecchi L, Al-Ahmad M, et al. Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization. World Allergy Organ J. 2015;8(1):25. https://doi.org/10.1186/s40413-015-0073-0.

    CAS  Article  Google Scholar 

  10. Da Silva IR, Nedel AS, Marques JRQ, Nolasco JLR. Excess of children's outpatient consultations due to asthma and bronchitis and the association between meteorological variables in Canoas City. Southern Brazil Int J Biometeorol. 2018;63(11):1517–24.

    Article  Google Scholar 

  11. Veremchuk LV, Mineeva EE, Vitkina TI, Gvozdenko TA, Golokhvast KS. Impact of atmospheric microparticles and heavy metals on external respiration function of urbanized territory population. Russ Open Med J. 2017;6(4). https://doi.org/10.15275/rusomj.2017.0402.

  12. Makra L, Puskas J, Matyasovszky I, Csepe Z, Lelovics E, Balint B, et al. Weather elements, chemical air pollutants and airborne pollen influencing asthma emergency room visits in Szeged, Hungary: performance of two objective weather classifications. Int J Biometeorol. 2015;59(9):1269–89. https://doi.org/10.1007/s00484-014-0938-x.

    Article  Google Scholar 

  13. Joo SY, Park MJ, Kim KH, Choi HJ, Chung TW, Kim YJ, et al. Cold stress aggravates inflammatory responses in an LPS-induced mouse model of acute lung injury. Int J Biometeorol. 2016;60(8):1217–25. https://doi.org/10.1007/s00484-015-1116-5.

    Article  Google Scholar 

  14. Kullmann T, Szipocs A. Variability of breath condensate pH may contribute to the better understanding of non-allergic seasonal respiratory diseases. Int J Biometeorol. 2017;61(9):1703–8. https://doi.org/10.1007/s00484-017-1397-y.

    Article  Google Scholar 

  15. Xu Z, Crooks JL, Davies JM, Khan AF, Hu W, Tong S. The association between ambient temperature and childhood asthma: a systematic review. Int J Biometeorol. 2018;62(3):471–81. https://doi.org/10.1007/s00484-017-1455-5.

    Article  Google Scholar 

  16. Minkailov KO, Abueva RM, Minkailov EK, Chamsutdino NU. Bronchial asthma and allergic diseases. Medicine: Saint Petersburg; 2008. (in Russian)

    Google Scholar 

  17. Veremchuk LV, Mineeva EE. The technology for assessing the response of the body in patients with respiratory pathology to the impact of the city’s air environment // materials of X international scientific conference “system analysis in medicine”. Blagoveshchensk; 2016. (in Russian).

  18. Zheng XY, Ding H, Jiang LN, Chen SW, Zheng JP, Qiu M, Zhou YX, Chen Q, Guan WJ. Association between air pollutants and asthma emergency room visits and hospital admissions in time series studies: a systematic review and meta-analysis. PLoS One. 2015;10(9).

  19. Hansel NN, Romero KM, Pollard SL, Pollard SL. Bose S, Psoter KJ, Underhill L, Johnson C, Williams D, Curriero FC, Breysse P, Koehler K, Checkley W, GASP study investigators. Ambient air pollution and variation in multiple domains of asthma morbidity among Peruvian children. Ann Am Thorac Soc. 2019;16:348–55.

    Google Scholar 

  20. Voronin NM. Fundamentals of medical and biological climatology. Medicine: Moscow; 1981. (in Russian)

    Google Scholar 

  21. Ho WC, Hartley WR, Myers L, Lin MH, Lin YS, Lien CH, et al. Air pollution, weather, and associated risk factors related to asthma prevalence and attack rate. Environ Res. 2007;104:402–9. https://doi.org/10.1016/j.envres.2007.01.007.

    CAS  Article  Google Scholar 

  22. Yang CY, Chen CC, Chen CY, Kuo HW. Air pollution and hospital admissions for asthma in a Subtropical City: Taipei, Taiwan. J Toxicol Environ Health Part A. 2007;70(2):111–7.

    CAS  Article  Google Scholar 

  23. Delamater PL, Finley AO, Banerjee S. An analysis of asthma hospitalizations, air pollution, and weather conditions in Los Angeles County. California Sci Total Environ. 2012;425:110–8.

    CAS  Article  Google Scholar 

  24. Wang KY, Chau TT. An association between air pollution and daily outpatient visits for respiratory disease in a heavy industry area. PLoS One. 2013;8. https://doi.org/10.1371/journal.pone.0075220.

  25. Lam HC, Li AM, Chan EY, Goggins WB. The short-term association between asthma hospitalisations, ambient temperature, other meteorological factors and air pollutants in Hong Kong: a time-series study. Thorax. 2016;71(12):1097–109.

    Article  Google Scholar 

  26. Masoumi K, Shoushtari MH, Forouzan A, Darian AA, Dastoorpoor M, Ebrahimzadeh P, et al. Rainfall-associated bronchospasm epidemics: the epidemiological effects of air pollutants and weather variables. Canadian Respirat J. 2017. https://doi.org/10.1155/2017/9252069.

  27. Hu Y, Xu Z, Jiang F, Li S, Liu S, Wu M, Yan C, Tan J, Yu G, Hu Y, Yin Y, Tong S. Relative impact of meteorological factors and air pollutants on childhood allergic diseases in Shanghai, China Sci Total Environ. 2019;1(706).

  28. Martínez-Rivera C, Garcia-Olive I, Stojanovic Z, Radua J, Ruiz MJ, Abad-Capa J. Association between air pollution and asthma exacerbations in Badalona, Barcelona (Spain), 2008–2016. Med Clínica. 2019;152:333–8.

    Article  Google Scholar 

  29. Zhang H, Liu S, Chen Z, Zu B, Zhao Y. Effects of variations in meteorological factors on daily hospital visits for asthma: a time-series study. Environ Res. 2020;182. https://doi.org/10.1016/j.envres.2020.109115.

  30. Veremchuk LV, Mineeva EE. Influence of the environment on the function of external respiration in patients with bronchial asthma. Congress proceedings of XXVII National Congress on respiratory diseases. Moscow: Design Press; 2017. (in Russian)

    Google Scholar 

  31. Veremchuk LV, Mineeva EE, Vitkina TI. The ecological dependence of external respiration function in patients with bronchial asthma, living in Vladivostok. Zdorov'e. Meditsinskaya ehkologiya. Nauka. 2017;71(4):31–5 (in Russian).

    Google Scholar 

  32. Mineeva EE, Veremchuk LV. The integral assessment of the influence of environmental factors on the functional state of respiratory system. Tihookeanskij meditsinskij zhurnal: application. 2016;3:80 (in Russian).

    Google Scholar 

  33. Russell J. Bronchial asthma. Book on Demand: Moscow; 2012. (in Russian)

    Google Scholar 

  34. Dadbakhs M, Khanjani N, Bahrampour A, Haghighi PS. Death from respiratory diseases and temperature in shiraz, Iran (2006–2011). Int J Biometeorol. 2017;61(2):239–46. https://doi.org/10.1007/s00484-016-1206-z.

    Article  Google Scholar 

  35. Luo L, Zhang F, Zhang W, Sun L, Li C, Huang D, et al. Markov chain-based acute effect estimation of air pollution on elder asthma hospitalization. J Healthc Eng. 2017;2017. https://doi.org/10.1155/2017/2463065.

  36. Weather and climate. Available online: http//www.pogodaiklimat.ru (accessed Nov 19 2018). (in Russian).

  37. Regional Internet resource. Available online: http://vestiregion.ru (accessed Nov 19 2018). (in Russian).

  38. Anan'ev VY, Zhigaev DS, Kislitsina LV, Kiku PF. Assessment of the influence of atmospheric air on the population health of Vladivostok and its features. Zdorov'e. Meditsinskaya ehkologiya. Nauka. 2012;49–50(3–4):79–82 (in Russian).

    Google Scholar 

  39. Bibikov MN, Kuchenko KM, Kiselev SA. A report about the state of the natural environment of the Primorsky region in 2008. Vladivostok: Dalpress; 2010. (in Russian)

    Google Scholar 

  40. Golokhvast KS. Atmospheric suspensions in the cities of the Far East. Vladivostok, Russia: Publishing office of FEFU; 2013. (in Russian)

    Google Scholar 

  41. Veremchuk LV, Yankova VI, Vitkina TI, Nazarenko AV, Golokhvast KS. Urban air pollution, climate and its impact on asthma morbidity. Asian Pac J Trop Biomed. 2016;6(1):76–9. https://doi.org/10.1016/j.apjtb.2015.10.001.

    Article  Google Scholar 

  42. Veremchuk LV, Tsarouhas K, Vitkina TI, Mineeva EE, Gvozdenko TA, Antonyuk MV, et al. Impact evaluation of environmental factors on respiratory function of asthma patients living in urban territory. Environ Pollut. 2018;235:489–96. https://doi.org/10.1016/j.envpol.2017.12.122.

    CAS  Article  Google Scholar 

  43. Borovikov VP. STATISTICA program for students and engineers. Moscow: Computer press; 2001. (in Russian)

    Google Scholar 

  44. Svinuhov VG, Svinuhov GV, Gorborukova TV. The assessment of atmospheric pollution in Vladivostok. Regional Issues of Hydrometeorology and Atmosphere Protection. 2000;10:13–27 (in Russian).

    Google Scholar 

  45. Abbasov PA, Odintsova EY. Calculation of wind load in the conditions of mountain relief and monsoon climate of Vladivostok. Bulletin of the Department of Building Sciences. 2007;11:29–31 (in Russian).

    Google Scholar 

  46. Patella V, Florio G, Magliacane D, Giuliano A, Crivellaro MA, Di Bartolomeo D, et al. Urban air pollution and climate change: “the Decalogue: allergy safe tree” for allergic and respiratory diseases care. Clin Mol Allergy. 2018;16:20. https://doi.org/10.1186/12948-018-0098-3.

    CAS  Article  Google Scholar 

  47. Barskova LS, Vitkina TI, Gvozdenko TA, Veremchuk LV, Golokhvast KS. Assessment of air pollution by small-sized suspended particulate matter in urbanized territories with various technogenic load (on the example of Vladivostok, Russia). Rus Open Med J. 2019;8(3).

  48. Liu HY, Dunea D, Iordache S, Pohoata A. A Review of Airborne Particulate Matter Effects on Young Children’s Respiratory Symptoms and Diseases. Atmosphere. 2018;9(4). https://doi.org/10.3390/atmos9040150.

  49. Vitkina TI, Veremchuk LV, Mineeva EE, Gvozdenko TA, Antonyuk MV, Novgorodtseva TP, et al. The influence of weather and climate on patients with respiratory diseases in Vladivostok as a global health implication. J Environ Health Sci Engineer. 2019;17(2):907–16.

    CAS  Article  Google Scholar 

  50. D’Amato M, Molino A, Calabrese G, Cecchi L, Annesi-Maesano I, D’Amato G. The impact of cold on the respiratory tract and its consequences to respiratory health. Clin Transl Allergy. 2018;8:20. https://doi.org/10.1186/s13601-018-0208-9.

    Article  Google Scholar 

  51. Zhang Y, Peng L, Kan H, Xu J, Chen R, Liu Y, et al. Effects of Meteorological Factors on Daily Hospital Admissions for Asthma in Adults: A Time-Series Analysis. PLoS One. 2014;9(7). https://doi.org/10.1371/journal.pone.0102475.

  52. Soneja S, Jiang C, Fisher J, Upperman CR, Mitchell C, Sapkota A. Exposure to extreme heat and precipitation events associated with increased risk of hospitalization for asthma in Maryland, USA. Environ Health. 2016;15(57). https://doi.org/10.1186/s12940-016-0142-z.

  53. Wang YC, Lin YK. Temperature effects on outpatient visits of respiratory diseases, asthma, and chronic airway obstruction in Taiwan. Int J Biometeorol. 2015;59(7):815–25. https://doi.org/10.1007/s00484-014-0899-0.

    Article  Google Scholar 

  54. Feng S, Gao D, Liao F, Zhou F, Wang X. The health effects of ambient PM2.5 and potential mechanisms. Ecotox Environ Safe. 2016;128:67–74.

    CAS  Article  Google Scholar 

  55. Longhin E, Holme JA, Gutzkow KB, Arlt VM, Kucab JE, Camatini M, Gualtieri M. Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: Characterization of the process and possible mechanisms involved. Part Fiber Toxicol. 2013;10(63).

  56. Atkinson RW, Mills IC, Walton HA, Anderson R. Fine particle components and health—a systematic review and meta-analysis of epi-demiological time series studies of daily mortality and hospital admissions. J Expo Sci Environ Epidemiol. 2015;25:208–14. https://doi.org/10.1038/jes.2014.63.

    CAS  Article  Google Scholar 

  57. Burnett RT, Brook J, Dann T, Delocla C, Philips O, Cakmak S, et al. Association between particulate- and gas-phase components of urban air pollution and daily mortality in eight Canadian cities. Inhal Toxicol. 2000;12:15–39. https://doi.org/10.1080/08958370050164851.

    CAS  Article  Google Scholar 

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Correspondence to Tatyana I. Vitkina.

Ethics declarations

Informed consent was obtained from all individual participants included in the study. All procedures performed in studies involving human participants complied with the ethical standards of Ethics Committee of the Vladivostok Branch of Federal State Budgetary Science Institution «Far Eastern Scientific Center of Physiology and Pathology of Respiration» – Institute of Medical Climatology and Rehabilitative Treatment (identification code of the protocol of the Ethics Committee: 10/12–11, approval date: December 07, 2011), and with the Declaration of Helsinki.

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Veremchuk, L.V., Mineeva, E.E., Vitkina, T.I. et al. The response ranges of pulmonary function and the impact criteria of weather and industrial influence on patients with asthma living in Vladivostok. J Environ Health Sci Engineer 18, 235–242 (2020). https://doi.org/10.1007/s40201-020-00458-z

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  • DOI: https://doi.org/10.1007/s40201-020-00458-z

Keywords

  • Weather
  • Industrial factors
  • Respiratory system
  • Pulmonary function
  • Asthma