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Prevalence and associated factors of painful diabetic peripheral neuropathy among diabetic patients on follow up at Jimma University Medical Center

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Abstract

Background

Despite having significant impact on the patient’s quality of life, painful diabetic peripheral neuropathy (PDPN) is usually underdiagnosed. Screening for PDPN in patients with diabetes is needed in order to get timely identification and management. Hence, the purpose of this study was to assess the prevalence and determinants of PDPN among diabetes patients attending outpatient at Jimma University Medical Center from September 1 November 10, 2019.

Methods

Hospital based cross-sectional study was conducted and douleur neuropathique-4 was used to identify the presence of PDPN. Data were collected using pretested structured questionnaire and entered into EPI data 3.1 and exported to SPSS version 20 for analysis. Both bivariate and multivariate binary logistic regression was employed to identify factors associated with PDPN. Variable having a p value of <0.25 in the bivariate model were considered as candidates for multivariable regression. Adjusted odds ratios were calculated at 95%CI and considered significant with a p value of <0.05.

Results

A total of 366 diabetic patients were enrolled into the study and their mean duration of diabetes was 6.8 ± 5.3 years. The study finding showed that the prevalence of PDPN was 14.5%. According to the multivariate logistic regression analysis smoking [current smoker(AOR = 6.17; 95%CI:2.25,16.86),former smoker(AOR = 3.22;95%CI:1.29,8.03)],diabetes duration[5 to 10 years (AOR = 3.32;95%CI:1.29,8.53), ≥ 10 years (AOR = 8.86;95% CI: 3.49,22.5)] and comorbid hypertension [AOR = 2.54; 95%CI:1.17,5.49] were independent predictors of PDPN among study participants.

Conclusion

The overall prevalence of PDPN in this study was 14.5% and it was significantly associated with smoking, comorbid hypertension and diabetes duration of above 5 years. Early detection and appropriate interventions are important for high risk patients identified in the current study.

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Abbreviations

AOR:

Adjusted odds ratio

BMI:

Body mass index

CI:

Confidence interval

COR:

Crude odds ratio

DM:

Diabetes mellitus

DN4:

Douleur Neuropathique-4

DPN:

Diabetic peripheral neuropathy

FBS:

Fasting blood sugar

JUMC:

Jimma University Medical Center

Htn:

Hypertension

PDPN:

Painful diabetic peripheral neuropathy

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Acknowledgments

I would like to acknowledge my study participants, data collectors and colleagues for their support. Lastly, I would like to thank Jimma University Medical Center staffs for providing me relevant information.

Funding

No funding was available for this work.

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Authors and Affiliations

  1. Department of Biomedical Sciences, College of Medical Sciences, Institute of Health Science, Jimma University, Jimma, Ethiopia

    Daba Abdissa

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  1. Daba Abdissa
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Correspondence to Daba Abdissa.

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Ethical approval and consent to participate

Ethical clearance was obtained from Jimma University Institutional Review Board. Oral informed consent was obtained from the study participants to start data collection. Information was recorded anonymously and their confidentiality was assured throughout the study period.

Competing interests

The authors of this study declare that has no competing interests.

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Abdissa, D. Prevalence and associated factors of painful diabetic peripheral neuropathy among diabetic patients on follow up at Jimma University Medical Center. J Diabetes Metab Disord 19, 1407–1413 (2020). https://doi.org/10.1007/s40200-020-00661-7

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