Evaluation of skin lesions in diabetic patients: a systematic review and meta-analysis



Prevalence of skin lesions among diabetic patients is a major health concern. Therefore, this systematic review and meta-analysis study was conducted to determine the prevalence of skin lesions in diabetic patients.


To identify and select relevant articles, the SID, MagIran, IranMedex, IranDoc, Google Scholar, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (WoS) databases were searched without a lower time limit and until April 2020. The random effects model was used to perform the analysis, and the heterogeneity of studies was assessed using the I2 index. Data were analyzed within the Comprehensive Meta-Analysis (Version 2) software.


After evaluating the 22 final articles with a total sample size of 8406, the prevalence of skin lesions among diabetes patients were found as 70.3% (95% CI: 63–76.7%). Moreover, according to the meta-regression analysis, the effect of ‘sample size’ on th prevalence of skin lesions was significantly different in diabetes patients (p < 0.05).


The results of this study show that skin lesions are common in diabetes patients. Therefore, appropriate policies needs to be adopted to improve the situation and to monitor patients and outcomes at all levels.

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Data availability

Datasets are available through the corresponding author upon reasonable request.



Diabetes mellitus


Strengthening the Reporting of Observational Studies in Epidemiology for cross- sectional Study


Preferred Reporting Items for Systematic Reviews and Meta-Analysis.


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The authors would like to thank the faculty members of the Faculty of Nursing and Midwifery, Kermanshah University of Medical Sciences for their support with this research.


SHR and NS and SHR contributed to the design, MM and RJ statistical analysis, participated in most of the study steps. SHSH and AHF and AVR and SHR and MHF and HK prepared the manuscript. NS and MM and SHR assisted in designing the study, and contributed to the interpretation of the study. All authors have read and approved the content of the manuscript.

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Correspondence to Shna Rasoulpoor or Masoud Mohammadi.

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Salari, N., Hosseinian-Far, A., Hosseinian-Far, M. et al. Evaluation of skin lesions in diabetic patients: a systematic review and meta-analysis. J Diabetes Metab Disord (2020). https://doi.org/10.1007/s40200-020-00629-7

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  • Skin lesions
  • Prevalence
  • Diabetes
  • Meta-analysis