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Mechanical property and biocompatibility of co-precipitated nano hydroxyapatite–gelatine composites

Journal of Advanced Ceramics volume 4, pages 237–243 (2015)Cite this article

Abstract

Uniform and well dispersed nano hydroxyapatite (HA)–gelatine composites were obtained by co-precipitation of hydroxyapatite and denatured calf skin collagen. The process allowed much higher concentration of hydroxyapatite to be produced over conventional hydrothermal process to improve the productivity. The effect of gelatine on the morphology, mechanical properties, and biocompatibility of hydroxyapatite particles was investigated. Fibroblast cell tests of the consolidated hydroxyapatite–gelatine composites showed that the composites have excellent biocompatibility.

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Author information

Affiliations

  1. School of Marine Science and Engineering, Plymouth University, London, UK

    Huirong Le

  2. Peninsular Schools of Medicine and Dentistry, Plymouth University, London, UK

    Kiruthika Natesan

  3. School of Engineering, Physics and Mathematics, University of Dundee, London, UK

    Sundaram Pranti-Haran

Authors
  1. Huirong Le
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  2. Kiruthika Natesan
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  3. Sundaram Pranti-Haran
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Correspondence to Huirong Le.

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Le, H., Natesan, K. & Pranti-Haran, S. Mechanical property and biocompatibility of co-precipitated nano hydroxyapatite–gelatine composites. J Adv Ceram 4, 237–243 (2015). https://doi.org/10.1007/s40145-015-0155-z

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  • DOI: https://doi.org/10.1007/s40145-015-0155-z

Keywords

  • biomaterials
  • nanocomposites
  • hydroxyapatite (HA)
  • gelatine
  • biocompatibility