Abstract
In the present study, we report a fabrication of dual-mode carbon coated gadolinia C@Gd2O3 particles by a facile hydrothermal synthesis method without using any organic solvents. The prepared C@Gd2O3 particles have a core-shell structure and a narrow size distribution in the range of 261±27 nm. The fluorescent properties of the prepared C@Gd2O3 particles were accessed by a room-temperature photoluminescence study, while the longitudinal relaxivity (r 1) was examined by using a clinical 1.5 T MRI scanner. A murine fibroblast L-929 cell line was used to examine the cytotoxicity and capability of the prepared C@Gd2O3 particles for the fluorescent labeling. The obtained results show that the prepared C@Gd2O3 particles could be used as a dual-mode contrast agent for magnetic resonance and fluorescence imaging.
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Atabaev, T.S., Lee, J.H., Han, DW. et al. Fabrication of carbon coated gadolinia particles for dual-mode magnetic resonance and fluorescence imaging. J Adv Ceram 4, 118–122 (2015). https://doi.org/10.1007/s40145-015-0139-z
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DOI: https://doi.org/10.1007/s40145-015-0139-z