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Chronic Pediatric Pain Management: a Review of Multidisciplinary Care and Emerging Topics

  • Pediatric Rehabilitation Medicine (A Houtrow and M Fuentes, Section Editors)
  • Published:
Current Physical Medicine and Rehabilitation Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Chronic pain is a prevalent, disabling, and expensive pediatric condition. Specific treatment options have limited evidence and are often extrapolated from adult care. This review evaluates pain outcome measures, psychological treatment, pharmacologic management, multidisciplinary treatment models, and emerging topics in pediatric pain medicine.

Recent Findings

Multimodal cognitive behavioral therapy and intensive interdisciplinary pain treatment have the strongest evidence for improving pain and function while decreasing healthcare utilization. There is emerging evidence that parental involvement in care is an important factor in pediatric outcomes. While there is increased interest in emerging topics such as use of marijuana-derived products, acupuncture, and virtual reality, the evidence behind such interventions remains limited.

Summary

Pediatric chronic pain treatment centers on the biopsychosocial model of pain and multidisciplinary treatment. Recent research shows that intensive interdisciplinary pain treatment can improve pain, function, and healthcare utilization. Long-term benefits and risks of emerging treatments in pediatric chronic pain remain poorly understood.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Merskey H, Bogduk N. Classification of chronic pain: descriptions of chronic pain syndromes and definitions of pain terms. Seattle: IASP Press; 1994.

    Google Scholar 

  2. Huguet A, Miro J. The severity of chronic pediatric pain: an epidemiological study. The Journal of Pain. 2008;9:226–36. https://doi.org/10.1016/j.jpain.2007.10.015.

    Article  PubMed  Google Scholar 

  3. King S, Chambers CT, Huguet A, MacNevin RC, McGrath PJ, Parker L, et al. The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain. 2011;152:2729–38. https://doi.org/10.1016/j.pain.2011.07.016.

    Article  PubMed  Google Scholar 

  4. Palermo T. Impact of recurrent and chronic pain on child and family daily functioning: a critical review of the literature. Dev Behav Pediatr. 2000;21:58–69. https://doi.org/10.1097/00004703-200002000-00011.

    Article  CAS  Google Scholar 

  5. Tumin D, Drees D, Miller R, Wrona S, Hayes D, Tobias JD, et al. Health care utilization and costs associated with pediatric chronic pain. J Pain. 2018;19:973–82. https://doi.org/10.1016/j.jpain.2018.03.012.

    Article  PubMed  Google Scholar 

  6. Groenewald CB, Essner BS, Wright D, Fesinmeyer MD, Palermo TM. The economic costs of chronic pain among a cohort of treatment-seeking adolescents in the United States. J Pain. 2014;15:925–33. https://doi.org/10.1016/j.jpain.2014.06.002.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Clementi MA, Kao GS, Monico E. Pain acceptance as a predictor of medical utilization and school absenteeism in adolescents with chronic pain. J Pediatr Psychol. 2018;43:294–302. https://doi.org/10.1093/jpepsy/jsx125.

    Article  PubMed  Google Scholar 

  8. Tian F, Guittar P, Moore-Clingenpeel M, Higgins G, Ardoin SP, Spencer CH, et al. Healthcare use patterns and economic burden of chronic musculoskeletal pain before diagnosis. J Pediatr. 2018;197:172–6. https://doi.org/10.1016/j.jpeds.2018.01.076.

    Article  PubMed  Google Scholar 

  9. Basch MC, Chow ET, Logan DE, Schechter NL, Simons LE. Perspectives on the clinical significance of functional pain syndromes in children. J Pain Res. 2015;8:675–86. https://doi.org/10.2147/JPR.S55586.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Schechter NL. Functional pain: time for a new name. JAMA Pediatr. 2014;168:693–4. https://doi.org/10.1001/jamapediatrics.2014.530.

    Article  PubMed  Google Scholar 

  11. Gatchel RJ, Peng YB, Peters ML, Fuchs PN, Turk DC. The biopsychosocial approach to chronic pain: scientific advances and future directions. Psychol Bull. 2007;133:581–624. https://doi.org/10.1037/0033-2909.133.4.581.

    Article  PubMed  Google Scholar 

  12. Vetter TR, McGwin G, Bridgewater CL, Madan-Swain A, Ascherman LI. Validation and clinical application of a biopsychosocial model of pain intensity and functional disability in patients with a pediatric chronic pain condition referred to a subspecialty clinic. Pain Res Treat. 2013;143292:1–12. https://doi.org/10.1155/2013/143292.

    Article  Google Scholar 

  13. Landry BW, Fischer PR, Driscoll SW, Koch KM, Harbeck-Weber C, Mack KJ, et al. Managing chronic pain in children and adolescents: a clinical review. PM R. 2015;7:S295–315. https://doi.org/10.1016/j.pmrj.2015.09.006.

    Article  PubMed  Google Scholar 

  14. • Miro J, McGrath PJ, Finley GA, Walco GA. Pediatric chronic pain programs: current and ideal practice. Pain Rep. 2017;2:e613. https://doi.org/10.1097/PR9.0000000000000613 This article provides survey results from current pediatric pain providers, describing characteristics of current pain programs and an ideal program. These results can help inform providers interested in starting or modifying a pediatric chronic pain program.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Tran ST, Jastrowski Mano KE, Hainsworth KR, Medrano GR, Anderson Khan K, Weisman DJ, et al. Distinct influences of anxiety and pain catastrophizing on functional outcomes in children and adolescents with chronic pain. J Pediatr Psychol. 2015;40:744–55. https://doi.org/10.1093/jpepsy/jsv029.

    Article  PubMed  Google Scholar 

  16. Katholi BR, Daghastani SS, Banez GA, Brady KK. Noninvasive treatments for pediatric complex regional pain syndrome: a focused review. PM&R. 2014;6:926–33. https://doi.org/10.1016/j.pmrj.2014.04.007.

    Article  Google Scholar 

  17. Namerow LB, Kutner EC, Wakefield EC, Rzepski BR, Sahl RA. Pain amplification syndrome: a biopsychosocial approach. Semin Pediatr Neurol. 2016;23:224–30. https://doi.org/10.1016/j.spen.2016.10.006.

    Article  PubMed  Google Scholar 

  18. Cucchiaro G, Schwartz J, Hutchason A, Ornelas B. Chronic pain in children: a look at the referral process to a pediatric pain clinic. Int J Pediatr. 2017;8769402:1–7. https://doi.org/10.1155/2017/8769402.

    Article  Google Scholar 

  19. Mathew E, Kim E, Goldschneider KR. Pharmacological treatment of chronic non-cancer pain in pediatric patients. Pediatr Drugs. 2014;16:457–71. https://doi.org/10.1007/s40272-014-0092-2.

    Article  Google Scholar 

  20. Shah RD, Cappiello D, Suresh S. Interventional procedures for chronic pain in children and adolescents: a review of the current evidence. Pain Pract. 2016;16:359–69. https://doi.org/10.1111/papr.12285.

    Article  PubMed  Google Scholar 

  21. •• Mahrer NE, Gold JI, Luu M, Herman PM. A cost-analysis of an interdisciplinary pediatric chronic pain clinic. J Pain. 2018;19:158–65. https://doi.org/10.1016/j.jpain.2017.09.008 This article describes an interdisciplinary outpatient pediatric pain clinic and demonstrates how such a clinic can save costs to hospitals and insurance companies.

    Article  PubMed  Google Scholar 

  22. Huguet A, Stinson JN, McGrath PJ. Measurement of self-reported pain intensity in children and adolescents. J Psychosom Res. 2010;68:329–36. https://doi.org/10.1016/j.jpsychores.2009.06.003.

    Article  PubMed  Google Scholar 

  23. Castarlenas E, Jensen MP, von Baeyer CL, Miro J. Psychometric properties of the numerical rating scale to assess self-reported pain intensity in children and adolescents: a systematic review. Clin J Pain. 2017;33:376–83. https://doi.org/10.1097/AJP.0000000000000406.

    Article  PubMed  Google Scholar 

  24. Young MA, Carter B, von Baeyer CL. Optimizing numeric pain rating scale administration for children: the effects of verbal anchor phrases. Can J Pain. 2017;1:191–8. https://doi.org/10.1080/24740527.2017.1398587.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Cook KF, Dunn W, Griffith JW, Morrison MT, Tanquary J, Sabata D, et al. Pain assessment using the NIH toolbox. Neurology. 2013;80:S49–53. https://doi.org/10.1212/WNL.0b013e3182872e80.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Jacob E, Puntillo KA. A survey of nursing practice in the assessment and management of pain in children. Pediatr Nurs. 1999;25:178–86.

    Google Scholar 

  27. Twycross A, Voepel-Lewis T, Vincent C, Franck LS, von Baeyer CL. A debate on the proposition that self- report is the gold standard in assessment of pediatric pain intensity. Clin J Pain. 2015;31:701–12. https://doi.org/10.1097/AJP.0000000000000165.

    Article  Google Scholar 

  28. Yetwin AK, Mahrer NE, John C, Gold JI. Does pain intensity matter? The relation between coping and quality of life in pediatric patients with chronic pain. J Pediatr Nurs. 2018;40:7–13. https://doi.org/10.1016/j.pedn.2018.02.003.

    Article  PubMed  Google Scholar 

  29. McGrath PJ, Walco GA, Turk DC, Dworkin RH, Brown MT, Davidson K, et al. Core outcome domains and measures of pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendations. J Pain. 2008;9:771–83. https://doi.org/10.1016/j.pain.2008.04.007.

    Article  PubMed  Google Scholar 

  30. Varni JW, Stucky BD, Thissen D, DeWitt EM, Irwin DE, Lai JS, et al. PROMIS pediatric pain interference scale: an item response theory analysis of the pediatric pain item bank. J Pain. 2010;11:1109–19. https://doi.org/10.1016/j.jpain.2010.02.005.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Claar RL, Walker LS. Functional assessment of pediatric pain patients: psychometric properties of the Functional Disability Inventory. Pain. 2006;121:77–84. https://doi.org/10.1016/j.pain.2005.12.002.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Kashikar-Zuck S, Flowers SR, Claar RL, Guite JW, Logan DE, Lynch-Jordan AM, et al. Clinical utility and validity of the Functional Disability Inventory among a multicenter sample of youth with chronic pain. Pain. 2011;152:1600–7. https://doi.org/10.1016/j.pain.2011.02.050.

    Article  PubMed  PubMed Central  Google Scholar 

  33. •• Coakley R, Wihak T. Evidence-based psychological interventions for the management of pediatric chronic pain: new directions in research and clinical practice. Children. 2017;4:E9. https://doi.org/10.3390/children4020009 This review article summarizes psychological treatment approaches for pediatric chronic pain, including descriptions and evidence base for different approaches.

    Article  PubMed  Google Scholar 

  34. Lynch-Jordan AM, Sil S, Cunningham NR, Joffe N, Slater SK, Tran ST, et al. Measuring treatment response in an outpatient pediatric pain program. Clinical Practice in Pediatric Psychology. 2015;3:1–11. https://doi.org/10.1037/cpp0000081.

    Article  Google Scholar 

  35. Lynch-Jordan AM, Sil S, Peugh J, Cunningham N, Kashikar-Zuk S, Goldschneider KR. Differential changes in functional disability and pain intensity over the course of psychological treatment for children with chronic pain. Pain. 2014;155:1955–61. https://doi.org/10.1016/j.pain.2014.06.008.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Palermo TM, Law EF, Zou C, Lewandowski A, Logan D, Tai G. Trajectories of change during a randomized controlled trial of Internet-delivered psychological treatment for adolescent chronic pain: how does change in pain and function relate? Pain. 2015;156:626–34. https://doi.org/10.1097/01.j.pain.0000460355.17246.6c.

    Article  PubMed  PubMed Central  Google Scholar 

  37. • Cunningham NR, Jagpal A, Tran ST, Kashikar-Zuck S, Goldschneider KR, Coghill RC, et al. Anxiety adversely impacts response to cognitive behavioral therapy in children with chronic pain. J Pediatr. 2016;171:227–33. https://doi.org/10.1016/j.jpeds.2016.01.018 This article shows that patients with untreated anxiety do not respond well to pain-focused cognitive behavioral therapy. This suggests that successful individualized pain treatment for such patients must also include anxiety management.

    Article  PubMed  PubMed Central  Google Scholar 

  38. Darnall BD, Scheman J, Davin S, Burns JW, Murphy JL, Wilson AC, et al. Pain psychology: a global needs assessment and national call to action. Pain Med. 2016;17:250–63. https://doi.org/10.1093/pm/pnv095.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Berde CB, Walco GA, Krane EJ, Anand KJS, Aranda JV, Craig KD, et al. Pediatric analgesic clinical trial designs, measures, and extrapolation: report of an FDA scientific workshop. Pediatrics. 2012;129:354–64. https://doi.org/10.1542/peds.2010-3591.

    Article  PubMed  Google Scholar 

  40. Gregoire MC, Finley GA. Drugs for chronic pain in children: a commentary on clinical practice and the absence of evidence. Pain Res Manag. 2013;18:47–50. https://doi.org/10.1155/2013/402863.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Guite JW, Sherry DD, Jarvis EW, Lewen MO, Khan S, Kraemer FW. Medication use among pediatric patients with chronic musculoskeletal pain syndromes at initial pain clinic evaluation. Pain Management. 2018;8:15–25. https://doi.org/10.2217/pmt-2017-0034.

    Article  Google Scholar 

  42. Gmuca S, Xiao R, Weiss PF, Sherry DD, Knight AM, Gerber JS. Opioid prescribing and polypharmacy in children with chronic musculoskeletal pain. Pain Medicine 2018 https://doi.org/10.1093/pm/pny116.

  43. • Stinson J, Harris L, Garofalo E, Lalloo C, Isaac L, Brown S, et al. Understanding the use of over-the-counter pain treatments in adolescents with chronic pain. Can J Pain. 2017;1:84–93. https://doi.org/10.1080/24740527.2017.1337468 This article provides qualitative information from interviews with adolescents who have chronic pain, including their use of over-the-counter medications, their perception of medications, and their decision-making process.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Rusy L, Troshynski TJ, Weisman SJ. Gabapentin in phantom limb pain management in children and young adults: report of seven cases. J Pain Symptom Manag. 2001;21:78–82. https://doi.org/10.1016/S0885-3924(00)00243-8.

    Article  CAS  Google Scholar 

  45. Butkovic D, Toljan S, Mihovilovic-Novak B. Experience with gabapentin for neuropathic pain in adolescents: report of five cases. Pediatr Anesth. 2006;16:325–9. https://doi.org/10.1111/j.1460-9592.2005.01687.x.

    Article  Google Scholar 

  46. Arnold LM, Schikler KN, Bateman L, Khan T, Pauer L, Bhadra-Brown P, et al. Safety and efficacy of pregabalin in adolescents with fibromyalgia: a randomized, double-blind, placebo- controlled trial and a 6-month open-label extension study. Pediatr Rheumatol. 2016;14:46. https://doi.org/10.1186/s12969-016-0106-4.

    Article  Google Scholar 

  47. Teitelbaum JE, Arora R. Long-term efficacy of low-dose tricyclic antidepressants for children with functional gastrointestinal disorders. J Pediatr Gastroenterol Nutr. 2011;53:260–4. https://doi.org/10.1097/MPG.0b013e318217df7c.

    Article  PubMed  Google Scholar 

  48. Patra KP, Sankararaman S, Jackson R, Hussain SZ. Significance of screening electrocardiogram before the initiation of amitriptyline therapy in children with functional abdominal pain. Clin Pediatr. 2012;51:848–51. https://doi.org/10.1177/0009922812447890.

    Article  Google Scholar 

  49. Titchen T, Cranswick N, Beggs S. Adverse drug reactions to nonsteroidal anti-inflammatory drugs, COX-2 inhibitors and paracetamol in a paediatric hospital. Br J Clin Pharmacol. 2005;59:718–23. https://doi.org/10.1111/j.1365-2125.2005.02444.x.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  50. Schechter NL. Pediatric pain management and opioids: the baby and the bathwater. JAMA Pediatr. 2014;168:987–8. https://doi.org/10.1001/jamapediatrics.2014.1441.

    Article  PubMed  Google Scholar 

  51. •• Powers SW, Coffey CS, Chamblerlin LA, Ecklund SJ, Klingner EA, Yankey JW, et al. Trial of amitriptyline, topiramate, and placebo for pediatric migraine. N Eng J Med. 2017;376:115–24. https://doi.org/10.1056/NEJMoa1610384 This randomized placebo-controlled trial of amitriptyline and topiramate for pediatric chronic headache showed no difference between topiramate or amitriptyline and placebo in improving headaches. This study is particularly important as one of few placebo-controlled medication trials in pediatric chronic pain.

    Article  CAS  Google Scholar 

  52. Powers SW, Hershey AD, Coffey CS. The childhood and adolescent migraine prevention (CHAMP) study: “what do we do now?”. Headache. 2017;57:180–3. https://doi.org/10.1111/head.13025.

    Article  PubMed  Google Scholar 

  53. Whitehouse WP. A quasi-placebo may have a role in some randomised controlled trials. Trials. 2018;19:92. https://doi.org/10.1186/s13063-018-2496-8.

    Article  PubMed  PubMed Central  Google Scholar 

  54. •• Hechler T, Kanstrup M, Holley AL, Simons LE, Wicksell R, Hirschfeld G, et al. Systematic review on intensive interdisciplinary pain treatment of children with chronic pain. Pediatrics. 2015;136:115–27. https://doi.org/10.1542/peds.2014-3319 This systematic review article describes various intensive interdisciplinary pain treatment programs and demonstrates that such programs can effectively improve function and pain intensity.

    Article  PubMed  Google Scholar 

  55. Logan DE, Conroy C, Sieberg CB, Simons LE. Changes in willingness to self-manage pain among children and adolescents and their parents enrolled in an intensive interdisciplinary pediatric pain treatment program. Pain. 2012;153:1863–70. https://doi.org/10.1016/j.pain.2012.05.027.

    Article  PubMed  Google Scholar 

  56. Bruce BK, Weiss KE, Ale CM, Harrison TE, Fischer PR. Development of an interdisciplinary pediatric pain rehabilitation program: the first 1000 consecutive patients. Mayo Clinic Proc. 2017;1:141–9. https://doi.org/10.1016/j.mayocpiqo.2017.05.006.

    Article  Google Scholar 

  57. • Evans JR, Benore E, Banez GA. The cost-effectiveness of intensive interdisciplinary pediatric chronic pain rehabilitation. J Pediatr Psychol. 2016;41:849–56. https://doi.org/10.1093/jpepsy/jsv100 This article shows that intensive interdisciplinary pain treatment can be cost-effective, even after accounting for the cost of the program.

    Article  PubMed  Google Scholar 

  58. Ruhe SK, Frosch M, Wagner J, Linder R, Pfenning I, Sauerland D, et al. Health care utilization and cost in children and adolescents with chronic pain: analysis of health care claims data 1 year before and after intensive interdisciplinary pain treatment. Clin J Pain. 2017;33:767–76. https://doi.org/10.1097/AJP.0000000000000460.

    Article  PubMed  Google Scholar 

  59. Sieberg CB, Smith A, White M, Manganella J, Sethna N, Logan DE. Changes in maternal and paternal pain-related attitudes, behaviors, and perceptions across pediatric pain rehabilitation treatment: a multilevel modeling approach. J Pediatr Psychol. 2017;42:52–64. https://doi.org/10.1093/jpepsy/jsw046.

    Article  PubMed  Google Scholar 

  60. Benore E, Brenner A, Banez GA, Wang L, Worley S. It takes two: parent functioning within the pediatric chronic pain experience and interdisciplinary rehabilitation treatment. Rehabil Psychol. 2018;63:205–14. https://doi.org/10.1037/rep0000177.

    Article  PubMed  Google Scholar 

  61. Kemani MK, Kanstrup M, Jordan A, Caes L, Gauntlett-Gilber J. Evaluation of an intensive interdisciplinary pain treatment based on acceptance and commitment therapy for adolescents with chronic pain and their parents: a nonrandomized clinical trial. J Pediatr Psychol. 2018;43:1–14. https://doi.org/10.1093/jpepsy/jsy031.

    Article  Google Scholar 

  62. Tran ST, Guite JW, Pantaleao A, Pfeiffer M, Myer GD, Sil S, et al. Preliminary outcomes of a cross-site cognitive–behavioral and neuromuscular integrative training intervention for juvenile fibromyalgia. Arthritis Care Res. 2017;69:413–20. https://doi.org/10.1002/acr.22946.

    Article  Google Scholar 

  63. Kashikar-Zuck S, Black WR, Pfeiffer M, Peugh J, Williams SE, Ting TV, et al. Pilot randomized trial of integrated cognitive-behavioral therapy and neuromuscular training for juvenile fibromyalgia: The FIT Teens Program. J Pain. 2018;19:1049–62. https://doi.org/10.1016/j.jpain.2018.04.003.

    Article  PubMed  PubMed Central  Google Scholar 

  64. National Conference of State Legislatures. State Medical Marijuana Laws [Internet]. 2018 [accessed 2018 November 14]. Available from: http://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx.

  65. Han B, Compton WM, Blanco C, Jones CM. Trends in and correlates of medical marijuana use among adults in the United States. Drug Alcohol Depend. 2018;186:120–9. https://doi.org/10.1016/j.drugalcdep.2018.01.022.

    Article  PubMed  Google Scholar 

  66. D’Souza DC, Ranganathan M. Medical marijuana: is the cart before the horse? JAMA. 2015;313:2431–2. https://doi.org/10.1001/jama.2015.6407.

    Article  PubMed  Google Scholar 

  67. Häuser W, Fitzcharles MA, Radbruch L, Petzke F. Cannabinoids in pain management and palliative medicine. Dtsch Arztebl Int. 2017;114:627–34. https://doi.org/10.3238/arztebl.2017.0627.

    Article  PubMed  PubMed Central  Google Scholar 

  68. • Wong SS, Wilens TW. Medical cannabinoids in children and adolescents: a systematic review. Pediatrics. 2017;140:e20171818. https://doi.org/10.1542/peds.2017-1818 This review is the most comprehensive review of medical use of marijuana-derived products for children and adolescents. While the review is not primarily about treating pain, it highlights the lack of research on this topic at this time.

    Article  PubMed  Google Scholar 

  69. Rudich Z, Stinson J, Jeavons M, Brown SC. Treatment of chronic intractable neuropathic pain with dronabinol: case report of two adolescents. Pain Res Manag. 2003;8:221–4. https://doi.org/10.1155/2003/675976.

    Article  PubMed  Google Scholar 

  70. Nugent SM, Morasco BJ, O’Neil ME, Freeman M, Low A, Kondo K, et al. The effects of cannabis among adults with chronic pain and an overview of general harms: a systematic review. Ann Intern Med. 2017;167:319–31. https://doi.org/10.7326/M17-0155.

    Article  PubMed  Google Scholar 

  71. Allan GM, Finley CR, Ton J, Perry D, Ramji J, Crawford K, et al. Systematic review of systematic reviews for medical cannabinoids: pain, nausea and vomiting, spasticity, and harms. Can Fam Physician. 2018;64:e78–94.

    PubMed  PubMed Central  Google Scholar 

  72. Bruce D, Brady JP, Foster E, Shattell M. Preferences for medical marijuana over prescription medications among persons living with chronic conditions: alternative, complementary, and tapering uses. J Altern Complement Med. 2017;24:1–8. https://doi.org/10.1089/acm.2017.0184.

    Article  Google Scholar 

  73. Lankenau SE, Ataiants J, Mohanty S, Schrager S, Iverson E, Wong CF. Health conditions and motivations for marijuana use among young adult medical marijuana patients and non-patient marijuana users. Drug Alcohol Rev. 2018;37:237–46. https://doi.org/10.1111//dar.12534.

    Article  PubMed  Google Scholar 

  74. Wang GS, Roosevelt G, Heard K. Pediatric marijuana exposures in a medical marijuana State. JAMA Pediatr. 2013;167:630–1. https://doi.org/10.1001/jamapediatrics.2013.140.

    Article  PubMed  Google Scholar 

  75. Thomas AA, Moser E, Dickerson-Young T, Mazor S. A review of pediatric marijuana exposure in the setting of increasing legalization. Clin Pediatr Emerg Med. 2017;18:159–62. https://doi.org/10.1016/j.cpem.2017.07.003.

    Article  Google Scholar 

  76. Chadi N, Weitzman ER, Levy S. Understanding the impact of national and state medical marijuana policies on adolescents. Curr Addict Rep. 2018;5:93–101. https://doi.org/10.1007/s40429-018-0191-1.

    Article  Google Scholar 

  77. Meier MH, Caspi A, Ambler A, Harrington H, Houts R, Keefe RS, McDonald K, Ward A, Poulton R, Moffitt TE. Persistent cannabis users show neuropsychological decline from childhood to midlife. Proc Natl Acad Sci U S A 2012:109:e2657–e2664. 0.1073/pnas.1206820109.

  78. National Center for Complementary and Integrative Health. Complementary, alternative, or integrative health: what’s in a name? [Internet]. 2017 [accessed 2018 November 14]. Available from: https://nccih.nih.gov/health/integrative-health.

  79. Black LI, Clarke TC, Barnes PM, Stussman BJ, Nahin RL. Use of complementary health approaches among children aged 4-17 years in the United States: National Health Interview Survey, 2007-2012. Natl Health Stat Rep. 2015;78:1–19.

    Google Scholar 

  80. • McClafferty H, Vohra S, Bailey M, Brown M, Esparham A, Gerstbacher D, et al. Pediatric integrative medicine. Pediatrics. 2017;140:e20171961. https://doi.org/10.1542/peds.2017-1961 This article summarizes attitudes regarding pediatric integrative medicine, as well as the evidence base for various forms of complementary and integrative medicine.

    Article  PubMed  Google Scholar 

  81. Faith J, Thorburn S, Tippens KM. Examining the association between patient-centered communication and provider avoidance, CAM use, and CAM-use disclosure. Altern Ther Health Med. 2015;21:30–5.

    PubMed  Google Scholar 

  82. Bodner K, D’Amico S, Luo M, Sommers E, Goldstein L, Neri C, et al. A cross-sectional review of the prevalence of integrative medicine in pediatric pain clinics across the United States. Complement Ther Med. 2018;38:79–84. https://doi.org/10.1016/j.ctim.2018.05.001.

    Article  PubMed  Google Scholar 

  83. Golianu B, Yeh AM, Brooks M. Acupuncture for pediatric pain. Children. 2014;1:134–48. https://doi.org/10.3390/children1020134.

    Article  PubMed  PubMed Central  Google Scholar 

  84. McDonald MJ. Acupuncture and acupuncture-related therapies are well-tolerated and can effectively provide pain relief in the pediatric population. Med Acupunct. 2015;27:481–6. https://doi.org/10.1089/acu.2015.1132.

    Article  Google Scholar 

  85. Yang C, Hao Z, Zhang LL, Guo Q. Efficacy and safety of acupuncture in children: an overview of systematic reviews. Pediatr Res. 2015;78:112–9. https://doi.org/10.1038/pr.2015.91.

    Article  PubMed  Google Scholar 

  86. Brittner M, Le Pertel N, Gold MA. Acupuncture in pediatrics. Curr Probl Pediatr Adolesc Health Care. 2016;46:179–83. https://doi.org/10.1016/j.cppeds.2015.12.005.

    Article  PubMed  Google Scholar 

  87. Won AS, Bailey J, Bailenson J, Tataru C, Yoon IA, Golianu B. Immersive virtual reality of pediatric pain. 2017:4:pii:e52. https://doi.org/10.3390/children4070052.

  88. Gupta A, Scott K, Dukewish M. Innovative technology using virtual reality in the treatment of pain: does it reduce pain via distraction, or is there more to it? Pain Med. 2018;19:151–9. https://doi.org/10.1093/pm/pnx109.

    Article  PubMed  Google Scholar 

  89. Shiri S, Feintuch U, Weiss N, Pustilnik A, Geffen T, Kay B, et al. A virtual reality system combined with biofeedback for treating pediatric chronic headache—a pilot study. Pain Med. 2013;14:621–7. https://doi.org/10.1111/pme.12083.

    Article  PubMed  Google Scholar 

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Correspondence to Andrew B. Collins.

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Collins, A.B. Chronic Pediatric Pain Management: a Review of Multidisciplinary Care and Emerging Topics. Curr Phys Med Rehabil Rep 7, 30–39 (2019). https://doi.org/10.1007/s40141-019-0211-7

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