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Indications for Emergent Hyperbaric Oxygen Therapy

  • Technology in Medicine (J Paxton and V Kumar, Section Editors)
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Abstract

Purpose of Review

This review describes select emergent indications for hyperbaric oxygen therapy (HBOT), current treatment protocols, and recent literature regarding its use.

Recent Findings

Recent reports have continued to support the emergent use of hyperbaric oxygen (HBO) and new applications for therapy.

Summary

Emergent hyperbaric oxygen therapy is indicated in several conditions due to its ability to reduce morbidity and mortality. Recent reports support its use in multiple emergent indications; however, additional research is required to refine treatment protocols, including time from symptom onset to initiation of treatment. In addition, the shortage of available facilities offering emergent HBOT poses a significant threat to patient care and research advances.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Jain KK. Textbook of hyperbaric medicine. 6th ed. Cham: Springer; 2017.

    Book  Google Scholar 

  2. •• Moon RE. Undersea and hyperbaric medical society hyperbaric oxygen therapy indications, 14th edition. Best Pub. Co, North Palm Beach, FL. 2019. This is the recently updated version of the UHMS indications for hyperbaric oxygen therapy, which includes literature reviews, utilization reviews, cost impacts, and AHA recommendations and level of evidence ratings.

  3. Wattel F. A History of Hyperbaric Medicine. In: Mathieu D (ed) Handbook on Hyperbaric Medicine. Springer Netherlands, Dordrecht. 2006;1–11

  4. Camporesi EM. Side effects of hyperbaric oxygen therapy. Undersea Hyperb Med. 2014;41:253–7.

    Google Scholar 

  5. Mitchell SJ, Bennett MH, Moon RE. Decompression sickness and arterial gas embolism. N Engl J Med. 2022;386:1254–64.

    Article  CAS  Google Scholar 

  6. Moon RE. Hyperbaric treatment of air or gas embolism: current recommendations. UHM. 2019:673–683.

  7. Mitchell SJ, Bennett MH, Bryson P, Butler FK, Doolette DJ, Holm JR, Kot J, Lafere P. Consensus guideline: pre-hospital management of decompression illness: expert review of key principles and controversies. Undersea Hyperb Med. 2018;45:273–86.

    Article  Google Scholar 

  8. Zamboni WA, Roth AC, Russell RC, Graham B, Suchy H, Kucan JO. Morphologic analysis of the microcirculation during reperfusion of ischemic skeletal muscle and the effect of hyperbaric oxygen. Plast Reconstr Surg. 1993;91:1110–23.

    Article  CAS  Google Scholar 

  9. Martin JD, Thom SR. Vascular leukocyte sequestration in decompression sickness and prophylactic hyperbaric oxygen therapy in rats. Aviat Space Environ Med. 2002;73:565–9.

    Google Scholar 

  10. Chau JC, Leung JK, Yan W. Gas embolism and hyperbaric oxygen therapy: a case series. Hong Kong Med J. 2021;27:362–5.

    Article  CAS  Google Scholar 

  11. Hatling D, Høgset A, Guttormsen AB, Müller B. Iatrogenic cerebral gas embolism-a systematic review of case reports. Acta Anaesthesiol Scand. 2019;63:154–60.

    Article  Google Scholar 

  12. Hendriksen SM, Menth NL, Westgard BC, Cole JB, Walter JW, Masters TC, Logue CJ. Hyperbaric oxygen therapy for the prevention of arterial gas embolism in food grade hydrogen peroxide ingestion. Am J Emerg Med. 2017;35:809.e5-809.e8.

    Article  Google Scholar 

  13. Halperin JL, Levine GN, Al-Khatib SM, et al. Further evolution of the ACC/AHA clinical practice guideline recommendation classification system: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2016;67:1572–4.

    Article  Google Scholar 

  14. Mitchell SJ. DCS or DCI? The difference and why it matters. Diving Hyperb Med. 2019;49:152–3.

    Article  Google Scholar 

  15. Moon RE, Mitchell SJ. Hyperbaric oxygen for decompression sickness: 2021 update. UHM. 2021:195–203.

  16. Hadanny A, Fishlev G, Bechor Y, Bergan J, Friedman M, Maliar A, Efrati S. Delayed recompression for decompression sickness: retrospective analysis. PLoS ONE. 2015;10:e0124919.

    Article  Google Scholar 

  17. Inman AL, Sorrell LP, Lagina AT. Decompression sickness responsive to delayed treatment with hyperbaric oxygen: a case report of two divers. UHM. 2020;551–554.

  18. Doolette D, Mitchell S. In-water recompression Diving Hyperb Med. 2018;48:84–95.

    Article  Google Scholar 

  19. Qing L, Yi H, Wang Y, Zhou Q, Ariyadewa DK, Xu W. Hyperbaric oxygen pretreatment benefits on decompression sickness in Bama pigs. J Exp Biol. 2017;jeb.171066

  20. Katsenelson K, Arieli Y, Abramovich A, Feinsod M, Arieli R. Hyperbaric oxygen pretreatment reduces the incidence of decompression sickness in rats. Eur J Appl Physiol. 2007;101:571–6.

    Article  Google Scholar 

  21. • Li Y, Xu X, Bao J, Wang W. Effects of hyperbaric oxygen pretreatment on brain antioxidant capacity in rats with decompression sickness. Undersea Hyperb Med. 2021;48:287–95. This is a recent animal study that suggested that pretreatment with hyperbaric oxygen has protective effects against brain injury in rats with decompression sickness.

    Article  Google Scholar 

  22. Clarke R. Health care worker decompression sickness: incidence, risk, and mitigation. Undersea Hyperb Med. 2017;44:509–19.

    Article  Google Scholar 

  23. Gelmann D, Jasani G, Moayedi S, Sward D. Inner ear decompression sickness in a hyperbaric chamber inside tender: a case report. Undersea Hyperb Med. 2021;48:443–8.

    Article  Google Scholar 

  24. Kot J, Lenkiewicz E, Lizak E, Góralczyk P, Chreptowicz U. Spinal cord decompression sickness in an inside attendant after a standard hyperbaric oxygen treatment session. Diving Hyperb Med. 2021;51:103–6.

    Article  Google Scholar 

  25. Hampson NB, Weaver LK. Carbon monoxide poisoning: a new incidence for an old disease. Undersea Hyperb Med. 2007;34:163–8.

    CAS  Google Scholar 

  26. Chenoweth JA, Albertson TE, Greer MR. Carbon monoxide poisoning. Crit Care Clin. 2021;37:657–72.

    Article  Google Scholar 

  27. Roughton FJW, Darling RC. The effect of carbon monoxide on the oxyhemoglobin dissociation curve. Am J Physiol. 1944;141:17–31.

    Article  CAS  Google Scholar 

  28. Jay GD, McKindley DS. Alterations in pharmacokinetics of carboxyhemoglobin produced by oxygen under pressure. Undersea Hyperb Med. 1997;24:165–73.

    CAS  Google Scholar 

  29. Weaver LK. Carbon monoxide poisoning. Undersea Hyperb Med. 2020;47:151–69.

    Article  Google Scholar 

  30. Pace N, Strajman E, Walker EL. Acceleration of carbon monoxide elimination in man by high-pressure oxygen. Science. 1950;111:652–4.

    Article  CAS  Google Scholar 

  31. •• Lee Y, Cha YS, Kim SH, Kim H. Effect of hyperbaric oxygen therapy initiation time in acute carbon monoxide poisoning. Crit Care Med. 2021;49:e910–9. This single-center retrospective analysis demonstrated that patients with acute carbon monoxide poisoning who received hyperbaric oxygen therapy within 6 h of carbon monoxide exposure had better neurocognitive prognoses after 6 months compared to those who received treatment between 6 and 24 h.

    Article  CAS  Google Scholar 

  32. Weaver LK, Hopkins RO, Chan KJ, Churchill S, Elliott CG, Clemmer TP, Orme JF, Thomas FO, Morris AH. Hyperbaric oxygen for acute carbon monoxide poisoning. N Engl J Med. 2002;347:1057–67.

    Article  CAS  Google Scholar 

  33. Thom SR, Taber RL, Mendiguren II, Clark JM, Hardy KR, Fisher AB. Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen. Ann Emerg Med. 1995;25:474–80.

    Article  CAS  Google Scholar 

  34. Raphael JC, Elkharrat D, Jars-Guincestre MC, Chastang C, Chasles V, Vercken JB, Gajdos P. Trial of normobaric and hyperbaric oxygen for acute carbon monoxide intoxication. Lancet. 1989;2:414–9.

    Article  CAS  Google Scholar 

  35. Scheinkestel CD, Bailey M, Myles PS, Jones K, Cooper DJ, Millar IL, Tuxen DV. Hyperbaric or normobaric oxygen for acute carbon monoxide poisoning: a randomised controlled clinical trial. Med J Aust. 1999;170:203–10.

    Article  CAS  Google Scholar 

  36. Casillas S, Galindo A, Camarillo-Reyes LA, Varon J, Surani SR. Effectiveness of hyperbaric oxygenation versus normobaric oxygenation therapy in carbon monoxide poisoning: a systematic review. Cureus. 2019;11: e5916.

    Google Scholar 

  37. Koren G, Sharav T, Pastuszak A, Garrettson LK, Hill K, Samson I, Rorem M, King A, Dolgin JE. A multicenter, prospective study of fetal outcome following accidental carbon monoxide poisoning in pregnancy. Reprod Toxicol. 1991;5:397–403.

    Article  CAS  Google Scholar 

  38. • Arslan A. Hyperbaric oxygen therapy in carbon monoxide poisoning in pregnancy: maternal and fetal outcome. Am J Emerg Med. 2021;43:41–5. This recent study demonstrated no adverse effects on mother and fetus with the use of hyperbaric oxygen on pregnant patients with carbon monoxide poisoning. It also showed that continued treatments are beneficial in cases with persistent fetal distress, even with asymptomatic mothers.

    Article  Google Scholar 

  39. Kosaki Y, Maeyama H, Nojima T, Obara T, Nakao A, Naito H. Carbon monoxide poisoning during pregnancy treated with hyperbaric oxygen. Clin Case Rep. 2021. https://doi.org/10.1002/ccr3.4138.

    Article  Google Scholar 

  40. Lawson-Smith P, Jansen EC, Hyldegaard O. Cyanide intoxication as part of smoke inhalation - a review on diagnosis and treatment from the emergency perspective. Scand J Trauma Resusc Emerg Med. 2011;19:14.

    Article  Google Scholar 

  41. Stevens DL, Bryant AE, Goldstein EJC. Necrotizing soft tissue infections. Infect Dis Clin North Am. 2021;35:135–55.

    Article  Google Scholar 

  42. Mandell GL. Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils. Infect Immun. 1974;9:337–41.

    Article  CAS  Google Scholar 

  43. Jacoby I. Necrotizing soft tissue infections. Undersea Hyperb Med. 2012;39:739–52.

    Google Scholar 

  44. Memar MY, Yekani M, Alizadeh N, Baghi HB. Hyperbaric oxygen therapy: antimicrobial mechanisms and clinical application for infections. Biomed Pharmacother. 2019;109:440–7.

    Article  CAS  Google Scholar 

  45. Hedetoft M, Bennett MH, Hyldegaard O. Adjunctive hyperbaric oxygen treatment for necrotising soft-tissue infections: a systematic review and meta-analysis. Diving Hyperb Med. 2021;51:34–43.

    Article  Google Scholar 

  46. Hedetoft M, Garred P, Madsen MB, Hyldegaard O. Hyperbaric oxygen treatment is associated with a decrease in cytokine levels in patients with necrotizing soft‐tissue infection. Physiol Rep. 2021. https://doi.org/10.14814/phy2.14757.

  47. Hedetoft M, Jensen PØ, Moser C, Vinkel J, Hyldegaard O. Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection. J Investig Med. 2021;69:1330–8.

    Article  Google Scholar 

  48. Hedetoft M, Moser C, Jensen PØ, Vinkel J, Hyldegaard O. Soluble ICAM-1 is modulated by hyperbaric oxygen treatment and correlates with disease severity and mortality in patients with necrotizing soft-tissue infection. J Appl Physiol. 2021;130:729–36.

    Article  CAS  Google Scholar 

  49. Riseman JA, Zamboni WA, Curtis A, Graham DR, Konrad HR, Ross DS. Hyperbaric oxygen therapy for necrotizing fasciitis reduces mortality and the need for debridements. Surgery. 1990;108:847–50.

    CAS  Google Scholar 

  50. Devaney B, Frawley G, Frawley L, Pilcher DV. Necrotising soft tissue infections: the effect of hyperbaric oxygen on mortality. Anaesth Intensive Care. 2015;43:685–92.

    Article  CAS  Google Scholar 

  51. Shaw JJ, Psoinos C, Emhoff TA, Shah SA, Santry HP. Not just full of hot air: hyperbaric oxygen therapy increases survival in cases of necrotizing soft tissue infections. Surg Infect (Larchmt). 2014;15:328–35.

    Article  Google Scholar 

  52. Wang C, Schwaitzberg S, Berliner E, Zarin DA, Lau J. Hyperbaric oxygen for treating wounds: a systematic review of the literature. Arch Surg. 2003;138:272–279; discussion 280.

  53. Jallali N, Withey S, Butler PE. Hyperbaric oxygen as adjuvant therapy in the management of necrotizing fasciitis. Am J Surg. 2005;189:462–6.

    Article  CAS  Google Scholar 

  54. Willy C, Rieger H, Vogt D. Hyperbaric oxygen therapy for necrotizing soft tissue infections: contra. Chirurg. 2012;83:960–72.

    Article  CAS  Google Scholar 

  55. Feres O, Feitosa MR, Ribeiro da Rocha JJ, Miranda JM, Dos Santos LE, Féres AC, de Camargo HP, Parra RS. Hyperbaric oxygen therapy decreases mortality due to Fournier’s gangrene: a retrospective comparative study. Med Gas Res. 2021;11:18–23.

    Article  CAS  Google Scholar 

  56. Ferreira AP, Vide SS, Fernandes TD, Coelho PM, Camacho OF. Hyperbaric oxygen therapy as an adjuvant to source control in necrotizing soft tissue infections. UHM. 2017;44:535–542.

  57. Suzuki H, Muramatsu K, Kubo T, Kawasaki M, Fujitani T, Tsukamoto M, Uchida S, Fujino Y, Matsuda S, Sakai A. Factors associated with mortality among patients with necrotizing soft tissue infections: an analysis of 4597 cases using the Diagnosis Procedure Combination Database. Int J Infect Dis. 2021;102:73–8.

    Article  CAS  Google Scholar 

  58. Kleban SK, Baynosa RC. The effect of hyperbaric oxygen on compromised grafts and flaps. UHM. 2020;635–648.

  59. Weber R, Silver A, Williams SJ, et al. Random flap survival with hyperbaric oxygen: daily versus twice-daily treatments. Undersea Hyperb Med. 2018;45:157–64.

    Article  Google Scholar 

  60. Chua ME, Kim JJK, Ming JM, De Jesus MJ, See MC, Bagli DJ, Rickard M, Koyle MA, Lorenzo AJ. The utilization of hyperbaric oxygenation therapy in hypospadias repair: a systematic review and meta-analysis. Int Urol Nephrol. 2022;54:273–85.

    Article  CAS  Google Scholar 

  61. Neheman A, Rappaport YH, Verhovsky G, Bush N, Snodgrass W, Lang E, Zisman A, Efrati S. Hyperbaric oxygen therapy for pediatric “hypospadias cripple”—evaluating the advantages regarding graft take. J Pediatr Urol. 2020;16:163.e1-163.e7.

    Article  Google Scholar 

  62. Van Meter KW. Severe Anemia. In: Moon, R. Undersea and hyperbaric medical society hyperbaric oxygen therapy indications, 14th edition. Best Pub. Co, North Palm Beach, Fl. 2019;293–300.

  63. Shoemaker WC, Appel PL, Kram HB. Tissue oxygen debt as a determinant of lethal and nonlethal postoperative organ failure. Crit Care Med. 1988;16:1117–20.

    Article  CAS  Google Scholar 

  64. Van Meter KW. A systematic review of the application of hyperbaric oxygen in the treatment of severe anemia: an evidence-based approach. Undersea Hyperb Med. 2005;32:61–83.

    Google Scholar 

  65. Long B, Koyfman A. Emergency medicine evaluation and management of anemia. Emerg Med Clin North Am. 2018;36:609–30.

    Article  Google Scholar 

  66. Johnson-Arbor K, Verstraete R. No bad blood—surviving severe anemia without transfusion. JAMA Intern Med. 2021;181:7–8.

    Article  Google Scholar 

  67. Graffeo C, Dishong W. Severe blood loss anemia in a Jehovah’s Witness treated with adjunctive hyperbaric oxygen therapy. Am J Emerg Med. 2013;31:756.e3-4.

    Article  Google Scholar 

  68. McLoughlin PL, Cope TM, Harrison JC. Hyperbaric oxygen therapy in the management of severe acute anaemia in a Jehovah’s witness. Anaesthesia. 1999;54:891–5.

    Article  CAS  Google Scholar 

  69. Thenuwara K, Thomas J, Ibsen M, Ituk U, Choi K, Nickel E, Goodheart MJ. Use of hyperbaric oxygen therapy and PEGylated carboxyhemoglobin bovine in a Jehovah’s Witness with life-threatening anemia following postpartum hemorrhage. Int J Obstet Anesth. 2017;29:73–80.

    Article  CAS  Google Scholar 

  70. Misra H, Lickliter J, Kazo F, Abuchowski A. Pegylated carboxyhemoglobin bovine (Sanguinate): results of a phase I clinical trial: sanguinate: phase I clinical trial results. Artif Organs. 2014;38:702–7.

    Article  CAS  Google Scholar 

  71. Stewart IP. Major crush injury Br Med J (Clin Res Ed). 1987;294:854–5.

    Article  CAS  Google Scholar 

  72. Torlincasi AM, Lopez RA, Waseem M. Acute compartment syndrome. StatPearls. 2022.

  73. Myers RAM. Hyperbaric oxygen therapy for trauma: crush injury, compartment syndrome, and other acute traumatic peripheral ischemias. Int Anesthesiol Clin. 2000;38:139–151

  74. Strauss MB. The role of hyperbaric oxygen for acute traumatic ischemias. UHM. 2022;233–248.

  75. McMillan TE, Gardner WT, Schmidt AH, Johnstone AJ. Diagnosing acute compartment syndrome—where have we got to? International Orthopaedics (SICOT). 2019;43:2429–35.

    Article  Google Scholar 

  76. Shah J. Hyperbaric oxygen therapy. The Journal of the American College of Certified Wound Specialists. 2010;2:9–13.

    Article  Google Scholar 

  77. Garcia-Covarrubias L, Mcswain NE, Van Meter K, Bell RM. Adjuvant hyperbaric oxygen therapy in the management of crush injury and traumatic ischemia: an evidence-based approach. Am Surg. 2005;71:144–51.

    Article  Google Scholar 

  78. Bouachour G, Cronier P, Gouello JP, Toulemonde JL, Talha A, Alquier P. Hyperbaric oxygen therapy in the management of crush injuries: a randomized double-blind placebo-controlled clinical trial. The Journal of Trauma: Injury, Infection, and Critical Care. 1996;41:333–9.

    Article  CAS  Google Scholar 

  79. Mendes AF Jr, Neto JD, Heringer EM, de Simoni LF, Pires DD, Labronici PJ. Hyperbaric oxygen therapy as treatment for bilateral arm compartment syndrome after CrossFit: case report and literature review. Undersea Hyperb Med. 2018;45:209–215.

  80. Lee S, Han J, Heo T. Successful adjunctive treatment of compartment syndrome due to acute isocyanate inhalation using hyperbaric oxygen therapy: case report. UHM. 2020:455–459.

  81. Yagishita K, Enomoto M, Takazawa Y, Fukuda J, Koga H. Effects of hyperbaric oxygen therapy on recovery acceleration in Japanese professional or semi-professional rugby players with grade 2 medial collateral ligament injury of the knee: a comparative non-randomized study. UHM. 2019;647–654.

  82. Moghadam N, Hieda M, Ramey L, Levine BD, Guilliod R. Hyperbaric oxygen therapy in sports musculoskeletal injuries. Med Sci Sports Exerc. 2020;52:1420–6.

    Article  Google Scholar 

  83. Murphy-Lavoie H, Butler F, Hagan C. Arterial insufficiencies central retinal artery occlusion. In: Hyperbaric oxygen therapy indications, 14th ed. Undersea and Hyperbaric Medical Society. 2019;15–30.

  84. Delaey C, van de Voorde J. Regulatory mechanisms in the retinal and choroidal circulation. Ophthalmic Res. 2000;32:249–56.

    Article  CAS  Google Scholar 

  85. Patz A. Oxygen inhalation in retinal arterial occlusion. Am J Ophthalmol. 1955;40:789–95.

    Article  CAS  Google Scholar 

  86. Murphy-Lavoie H, Butler F, Hagan C. Central retinal artery occlusion treated with oxygen: a literature review and treatment algorithm. Undersea Hyperbaric Medicine. 2012;39:943–53.

    CAS  Google Scholar 

  87. Hadanny A, Maliar A, Fishlev G, Bechor Y, Bergan J, Friedman M, Avni I, Efrati S. Reversibility of retinal ischemia due to central retinal artery occlusion by hyperbaric oxygen. Clin Ophthalmol. 2017;11:115–25.

    Article  CAS  Google Scholar 

  88. Kim Y-S, Nam M-S, Park EJ, Lee Y, Kim SH, Cha YS. The effect of adjunctive hyperbaric oxygen therapy in patients with central retinal artery occlusion. UHM. 2020;57–64.

  89. Çevik MÖ, Bagli BS, Çevik SG. Hyperbaric oxygen treatment results in a group of Turkish central retinal artery occlusion patients with a combined presence of thrombophilic mutations. Undersea Hyperb Med. 2020;47:65–73.

    Article  Google Scholar 

  90. Schmidt I, Walter P, Siekmann U, Plange N, Koutsonas A, Mazinani BE, Kuerten D. Development of visual acuity under hyperbaric oxygen treatment (HBO) in non arteritic retinal branch artery occlusion. Graefes Arch Clin Exp Ophthalmol. 2020;258:303–10.

    Article  CAS  Google Scholar 

  91. Mcmonnies CW. Hyperbaric oxygen therapy and the possibility of ocular complications or contraindications. Clin Exp Optom. 2015;98:122–5.

    Article  Google Scholar 

  92. Bennett MH, Mitchell SJ. Emerging indications for hyperbaric oxygen. Curr Opin Anaesthesiol. 2019;32:792–8.

    Article  Google Scholar 

  93. Butler FK, Moon RE. Emergency hyperbaric oxygen therapy: a service in need of resuscitation - an open letter. Undersea Hyperb Med. 2020;47:649–52.

    Article  Google Scholar 

  94. Whitepaper: Access to emergent hyperbaric oxygen (Hbo2) therapy: an urgent problem in health care delivery in the United States. Undersea Hyperb Med 2020;47:652–657

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  1. Detroit Medical Center, Detroit Receiving Hospital, Wayne State University, Detroit, MI, USA

    Roxanne Ilagan, Madalyn Winarski & Anthony Lagina

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  1. Roxanne Ilagan
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Correspondence to Roxanne Ilagan.

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Ilagan, R., Winarski, M. & Lagina, A. Indications for Emergent Hyperbaric Oxygen Therapy. Curr Emerg Hosp Med Rep 10, 134–142 (2022). https://doi.org/10.1007/s40138-022-00251-2

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