Current Ophthalmology Reports

, Volume 6, Issue 2, pp 152–156 | Cite as

The Safety, Efficacy, and Potential Complications of Intracameral Antibiotics

  • Andrew Tye
  • Andre J. Witkin
Ocular Microbiology and Immunology (B Jeng and L Schocket, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Ocular Microbiology and Immunology


Purpose of Review

The use of intracameral antibiotics (ICAs) as endophthalmitis prophylaxis after cataract surgery has increased in the past decade. The goal of this paper is to review the current literature arguing for and against ICAs.

Recent Findings

There is compelling evidence that ICAs have greater efficacy than topical antibiotics in preventing post-operative endophthalmitis. However, issues related to availability, cost, and safety have limited their widespread adoption in countries such as the USA.


In countries without access to a commercially available prepackaged antibiotic for intracameral use, cataract surgeons will have to individually weigh the risks and benefits of ICAs in determining their method of endophthalmitis prophylaxis.


Intracameral antibiotics Cataract surgery Endophthalmitis Hemorrhagic occlusive retinal vasculitis 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Ophthalmology, Tufts Medical Center, New England Eye CenterBostonUSA

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