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Imaging of Patients with Renal Colic: A Paradigm Shift

  • Dual Energy CT (S Nicolaou and M Patlas, Section Editors)
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Abstract

Renal colic—which typically manifests as paroxysmal waves of intense flank pain often radiating to the groin—results from ureteral peristalsis during passage of, or obstruction by, renal calculi. It is commonly encountered in the emergency department (ED) in patients of all age groups. In fact, the incidence of renal colic continues to increase, and currently accounts for nearly 2 % of all adult visits to the ED in the United States. The initial steps in assessing such patients beyond a good history, physical examination, and urinalysis involve the utilization of imaging. In this review, we examine the current trends and controversies in the imaging of patients who present with renal colic. We also discuss the factors affecting the selection of imaging modalities, and highlight the emerging role of ultrasound as a safe and reliable option in patients with suspected urolithiasis.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Teichman JM. Clinical practice. Acute renal colic from ureteral calculus. New Engl J Med. 2004;350(7):684–93.

    Article  CAS  PubMed  Google Scholar 

  2. Fwu CW, Eggers PW, Kimmel PL, Kusek JW, Kirkali Z. Emergency department visits, use of imaging, and drugs for urolithiasis have increased in the United States. Kidney Int. 2013;83(3):479–86.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Hyams ES, Korley FK, Pham JC, Matlaga BR. Trends in imaging use during the emergency department evaluation of flank pain. J Urol. 2011;186(6):2270–4.

    Article  PubMed  Google Scholar 

  4. Taylor EN, Stampfer MJ, Curhan GC. Obesity, weight gain, and the risk of kidney stones. JAMA. 2005;293(4):455–62.

    Article  CAS  PubMed  Google Scholar 

  5. Taylor EN, Stampfer MJ, Curhan GC. Diabetes mellitus and the risk of nephrolithiasis. Kidney Int. 2005;68(3):1230–5.

    Article  PubMed  Google Scholar 

  6. Kant AK, Graubard BI, Atchison EA. Intakes of plain water, moisture in foods and beverages, and total water in the adult US population–nutritional, meal pattern, and body weight correlates: National Health and Nutrition Examination Surveys 1999-2006. Am J Clin Nutr. 2009;90(3):655–63.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Wallace RB, Wactawski-Wende J, O’Sullivan MJ, et al. Urinary tract stone occurrence in the Women’s Health Initiative (WHI) randomized clinical trial of calcium and vitamin D supplements. Am J Clin Nutr. 2011;94(1):270–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Rucker CM, Menias CO, Bhalla S. Mimics of renal colic: alternative diagnoses at unenhanced helical CT. Radiographics. 2004;24(Suppl 1):S11–28 discussion S-33.

    Article  PubMed  Google Scholar 

  9. Abdel-Gawad M, Kadasne R, Anjikar C, Elsobky E. Value of color doppler ultrasound, kub and urinalysis in diagnosis of renal colic due to ureteral stones. Int Braz J Urol. 2014;40(4):513–9.

    Article  PubMed  Google Scholar 

  10. Bove P, Kaplan D, Dalrymple N, et al. Reexamining the value of hematuria testing in patients with acute flank pain. J Urol. 1999;162(3 Pt 1):685–7.

    Article  CAS  PubMed  Google Scholar 

  11. Ozcan C, Aydogdu O, Senocak C, et al. Predictive factors for spontaneous stone passage and the potential role of serum C-reactive protein in patients with 4 to 10 mm distal ureteral stones: a prospective clinical study. J Urol. 2015;194(4):1009–13.

    Article  PubMed  Google Scholar 

  12. Pearle MS, Calhoun EA, Curhan GC. Urologic diseases of America P. Urologic diseases in America project: urolithiasis. J Urol. 2005;173(3):848–57.

    Article  PubMed  Google Scholar 

  13. Smith RC, Rosenfield AT, Choe KA, et al. Acute flank pain: comparison of non-contrast-enhanced CT and intravenous urography. Radiology. 1995;194(3):789–94.

    Article  CAS  PubMed  Google Scholar 

  14. Smith RC, Verga M, McCarthy S, Rosenfield AT. Diagnosis of acute flank pain: value of unenhanced helical CT. AJR Am J Roentgenol. 1996;166(1):97–101.

    Article  CAS  PubMed  Google Scholar 

  15. Miller OF, Rineer SK, Reichard SR, et al. Prospective comparison of unenhanced spiral computed tomography and intravenous urogram in the evaluation of acute flank pain. Urology. 1998;52(6):982–7.

    Article  CAS  PubMed  Google Scholar 

  16. Smith RC, Varanelli M. Diagnosis and management of acute ureterolithiasis: CT is truth. AJR Am J Roentgenol. 2000;175(1):3–6.

    Article  CAS  PubMed  Google Scholar 

  17. Dalziel PJ, Noble VE. Bedside ultrasound and the assessment of renal colic: a review. Emerg Med J. 2013;30(1):3–8.

    Article  PubMed  Google Scholar 

  18. Katz DS, Scheer M, Lumerman JH, Mellinger BC, Stillman CA, Lane MJ. Alternative or additional diagnoses on unenhanced helical computed tomography for suspected renal colic: experience with 1000 consecutive examinations. Urology. 2000;56(1):53–7.

    Article  CAS  PubMed  Google Scholar 

  19. Roth CS, Bowyer BA, Berquist TH. Utility of the plain abdominal radiograph for diagnosing ureteral calculi. Ann Emerg Med. 1985;14(4):311–5.

    Article  CAS  PubMed  Google Scholar 

  20. Mutgi A, Williams JW, Nettleman M. Renal colic. Utility of the plain abdominal roentgenogram. Arch Intern Med. 1991;151(8):1589–92.

    Article  CAS  PubMed  Google Scholar 

  21. Levine JA, Neitlich J, Verga M, Dalrymple N, Smith RC. Ureteral calculi in patients with flank pain: correlation of plain radiography with unenhanced helical CT. Radiology. 1997;204(1):27–31.

    Article  CAS  PubMed  Google Scholar 

  22. Kenney PJ. CT evaluation of urinary lithiasis. Radiol Clin North Am. 2003;41(5):979–99.

    Article  PubMed  Google Scholar 

  23. Broder J, Bowen J, Lohr J, Babcock A, Yoon J. Cumulative CT exposures in emergency department patients evaluated for suspected renal colic. J Emerg Med. 2007;33(2):161–8.

    Article  PubMed  Google Scholar 

  24. Pfister SA, Deckart A, Laschke S, et al. Unenhanced helical computed tomography vs intravenous urography in patients with acute flank pain: accuracy and economic impact in a randomized prospective trial. Eur Radiol. 2003;13(11):2513–20.

    Article  CAS  PubMed  Google Scholar 

  25. Coursey CA, Casalino DD, Remer EM, et al. ACR appropriateness criteria(R) acute onset flank pain–suspicion of stone disease. Ultrasound Q. 2012;28(3):227–33.

    Article  PubMed  Google Scholar 

  26. Katz SI, Saluja S, Brink JA, Forman HP. Radiation dose associated with unenhanced CT for suspected renal colic: impact of repetitive studies. Am J Roentgenol. 2006;186(4):1120–4.

    Article  Google Scholar 

  27. Westphalen AC, Hsia RY, Maselli JH, Wang R, Gonzales R. Radiological imaging of patients with suspected urinary tract stones: national trends, diagnoses, and predictors. Acad Emerg Med. 2011;18(7):699–707.

    Article  PubMed  PubMed Central  Google Scholar 

  28. • Smith-Bindman R, Aubin C, Bailitz J, et al. Ultrasonography versus computed tomography for suspected nephrolithiasis. New Engl J Med. 2014;371(12):1100–10. This study compared CT KUB and renal ultrasound for patients with suspected nephrolithiasis. They found that if a patient is worked-up initially with ultrasound, this was associated with lower cumulative radiation exposure, without significant differences in high-risk diagnoses, serious adverse events, return emergency department visits or hospitalizations.

  29. Tack D, Sourtzis S, Delpierre I, de Maertelaer V, Gevenois PA. Low-dose unenhanced multidetector CT of patients with suspected renal colic. Am J Roentgenol. 2003;180(2):305–11.

    Article  Google Scholar 

  30. Mulkens TH, Daineffe S, De Wijngaert R, et al. Urinary stone disease: comparison of standard-dose and low-dose with 4D MDCT tube current modulation. Am J Roentgenol. 2007;188(2):553–62.

    Article  Google Scholar 

  31. Poletti PA, Platon A, Rutschmann OT, Schmidlin FR, Iselin CE, Becker CD. Low-dose versus standard-dose CT protocol in patients with clinically suspected renal colic. Am J Roentgenol. 2007;188(4):927–33.

    Article  Google Scholar 

  32. Tartari S, Rizzati R, Righi R, Deledda A, Terrani S, Benea G. Low-dose unenhanced CT protocols according to individual body size for evaluating suspected renal colic: cumulative radiation exposures. Radiol Med (Torino). 2010;115(1):105–14.

    Article  CAS  Google Scholar 

  33. Heneghan JP, McGuire KA, Leder RA, DeLong DM, Yoshizumi T, Nelson RC. Helical CT for nephrolithiasis and ureterolithiasis: comparison of conventional and reduced radiation-dose techniques. Radiology. 2003;229(2):575–80.

    Article  PubMed  Google Scholar 

  34. Kalra MK, Maher MM, Toth TL, et al. Strategies for CT radiation dose optimization. Radiology. 2004;230(3):619–28.

    Article  PubMed  Google Scholar 

  35. Meagher T, Sukumar VP, Collingwood J, et al. Low dose computed tomography in suspected acute renal colic. Clin Radiol. 2001;56(11):873–6.

    Article  CAS  PubMed  Google Scholar 

  36. Patatas K, Panditaratne N, Wah TM, Weston MJ, Irving HC. Emergency department imaging protocol for suspected acute renal colic: re-evaluating our service. Br J Radiol. 1016;2012(85):1118–22.

    Google Scholar 

  37. Chowdhury FU, Kotwal S, Raghunathan G, Wah TM, Joyce A, Irving HC. Unenhanced multidetector CT (CT KUB) in the initial imaging of suspected acute renal colic: evaluating a new service. Clin Radiol. 2007;62(10):970–7.

    Article  CAS  PubMed  Google Scholar 

  38. Zwank MD, Ho BM, Gresback D, Stuck LH, Salzman JG, Woster WR. Does computed tomographic scan affect diagnosis and management of patients with suspected renal colic? Am J Emerg Med. 2014;32(4):367–70.

    Article  PubMed  Google Scholar 

  39. Moore CL, Scoutt L. Sonography first for acute flank pain? J Ultrasound Med. 2012;31(11):1703–11.

    PubMed  Google Scholar 

  40. • Turk C, Petrik A, Sarica K, et al. EAU guidelines on diagnosis and conservative management of urolithiasis. Eur Urol. 2016;69(3):468–74. This paper discussed in detail the most recent European Association of Urology guidelines on the diagnosis and conservative managemt of urolithiasis. The guidelines clearly state that ultrasound should be used as the primary diagnostic imaging tool, however, pain relief and other emergency measures should not be delayed by imaging assessments.

  41. Patlas M, Farkas A, Fisher D, Zaghal I, Hadas-Halpern I. Ultrasound vs CT for the detection of ureteric stones in patients with renal colic. Br J Radiol. 2001;74(886):901–4.

    Article  CAS  PubMed  Google Scholar 

  42. • Ripolles T, Martinez-Perez MJ, Vizuete J, Miralles S, Delgado F, Pastor-Navarro T. Sonographic diagnosis of symptomatic ureteral calculi: usefulness of the twinkling artifact. Abdom Imaging. 2013;38(4):863–9. This paper confirmed the improved sensitivity and specificity of renal ultrasound for detecting urolithiaisis with the utilization of the ‘twinkle artifact’. This technique was especially useful for calculi in the mid ureter. The use of Doppler did not increase the examination time.

  43. Taylor M, Woo MY, Pageau P, et al. Ultrasonography for the prediction of urological surgical intervention in patients with renal colic. Emerg Med J. 2016;33(2):118–23.

    Article  Google Scholar 

  44. • Yan JW, McLeod SL, Edmonds ML, Sedran RJ, Theakston KD. Normal renal sonogram identifies renal colic patients at low risk for urologic intervention: a prospective cohort study. CJEM. 2015;17(1):38–45. This article demonstrated that a normal renal ultrasound predicts a low likelihood for urologic intervention within 90 days for adult ED patients with suspected urolithiasis.

  45. Edmonds ML, Yan JW, Sedran RJ, McLeod SL, Theakston KD. The utility of renal ultrasonography in the diagnosis of renal colic in emergency department patients. CJEM. 2010;12(3):201–6.

    PubMed  Google Scholar 

  46. Nicolau C, Claudon M, Derchi LE, et al. Imaging patients with renal colic-consider ultrasound first. Insights Imaging. 2015;6(4):441–7.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Dalla Palma L, Stacul F, Bazzocchi M, Pagnan L, Festini G, Marega D. Ultrasonography and plain film versus intravenous urography in ureteric colic. Clinical Radiol. 1993;47(5):333–6.

    Article  CAS  Google Scholar 

  48. van Randen A, Lameris W, van Es HW, et al. A comparison of the accuracy of ultrasound and computed tomography in common diagnoses causing acute abdominal pain. Eur Radiol. 2011;21(7):1535–45.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Regan F, Bohlman ME, Khazan R, Rodriguez R, Schultze-Haakh H. MR urography using HASTE imaging in the assessment of ureteric obstruction. Am J Roentgenol. 1996;167(5):1115–20.

    Article  CAS  Google Scholar 

  50. Zielonko J, Studniarek M, Markuszewski M. MR urography of obstructive uropathy: diagnostic value of the method in selected clinical groups. Eur Radiol. 2003;13(4):802–9.

    CAS  PubMed  Google Scholar 

  51. Stothers L, Lee LM. Renal colic in pregnancy. J Urol. 1992;148(5):1383–7.

    CAS  PubMed  Google Scholar 

  52. Wieseler KM, Bhargava P, Kanal KM, Vaidya S, Stewart BK, Dighe MK. Imaging in pregnant patients: examination appropriateness. Radiographics. 2010;30(5):1215–29 discussion 30–3.

    Article  PubMed  Google Scholar 

  53. White WM, Zite NB, Gash J, Waters WB, Thompson W, Klein FA. Low-dose computed tomography for the evaluation of flank pain in the pregnant population. J Endourol. 2007;21(11):1255–60.

    Article  PubMed  Google Scholar 

  54. Roy C, Saussine C, Jahn C, et al. Fast imaging MR assessment of ureterohydronephrosis during pregnancy. Magn Reson Imaging. 1995;13(6):767–72.

    Article  CAS  PubMed  Google Scholar 

  55. Moore CL, Bomann S, Daniels B, et al. Derivation and validation of a clinical prediction rule for uncomplicated ureteral stone–the STONE score: retrospective and prospective observational cohort studies. BMJ. 2014;348:g2191.

    Article  PubMed  PubMed Central  Google Scholar 

  56. Schoenfeld EM, Poronsky KE, Elia TR, Budhram GR, Garb JL, Mader TJ. Validity of STONE scores in younger patients presenting with suspected uncomplicated renal colic. Am J Emerg Med. 2016;34(2):230–4.

    Article  PubMed  Google Scholar 

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Correspondence to Michael N. Patlas.

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Alabousi, A., Dreizin, D. & Patlas, M.N. Imaging of Patients with Renal Colic: A Paradigm Shift. Curr Radiol Rep 4, 27 (2016). https://doi.org/10.1007/s40134-016-0156-x

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