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MRI Evaluation of Pediatric Malignant Abdominal Tumors

  • MRI for Pediatric Oncology (H Lederman, Section Editor)
  • Published:
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Abstract

Mostly, pediatric abdominal tumors are benign. Eventually, malignant cancer may occur as abdominal tumor being the Wilms tumor, neuroblastoma, hepatoblastoma, and Burkitt’s lymphoma found to be common on this age group. Abdominal tumors can have a wide etiology range that can be classified according to its location, age group, and associated signs and symptoms. Mostly, benign findings are hydronephrosis, infectious hepatosplenomegaly, and ascariasis, while neuroblastoma, Wilms tumor, and germ cell tumors can exhibit specific MRI findings helping on its determination. This article discuss some clinical and MRI presentation of main abdominal pediatric malignances, as well as imaging findings that can correlate to clinical aspects to help during staging and patients’ treatment follow up.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. •• Gunderman RB, Transue DL. Radiology’s role in the battle against pediatric cancers. Acad Radiol. 2012;19(10):1300–3. This article describes the importance of radiology use against pediatric cancer.

  2. Lonergan GJ, Schwab CM, Suarez ES, Carlson CL. Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation. Radiographics. 2002;22(4):911–34.

    Article  PubMed  Google Scholar 

  3. • Crane GL, Hernanz-Schulman M. Current imaging assessment of congenital abdominal masses in pediatric patients. Semin Roentgenol. 2012;47(1):32–44. Article reviewing congenital abdominal masses in pediatric patients.

  4. Monclair T, Brodeur GM, Ambros PF, et al. The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol. 2009;27(2):298–303.

    Article  PubMed Central  PubMed  Google Scholar 

  5. •• Brisse HJ, McCarville MB, Granata C, et al. Guidelines for imaging and staging of neuroblastic tumors: consensus report from the International Neuroblastoma Risk Group Project. Radiology 2011;261(1):243–57. This article describes guidelines for imaging and stagind neuroblastic tumors.

  6. Rajiah P, Sinha R, Cuevas C, Dubinsky TJ, Bush WH Jr, Kolokythas O. Imaging of uncommon retroperitoneal masses. Radiographics. 2011;31(4):949–76.

    Article  PubMed  Google Scholar 

  7. • Goenka AH, Shah SN, Remer EM. Imaging of the retroperitoneum. Radiol Clin N Am 2012;50(2):333–55. This article discusses clinically relevant anatomy of the abdominal retroperitoneal spaces and the imaging features of common pathologic processes.

  8. Nour-Eldin NA, Abdelmonem O, Tawfik AM, Naguib NNN, Klingebiel T, et al. Pediatric primary and metastatic neuroblastoma: MRI findings pictorial review. Magn Reson Imaging. 2012;30(7):893–906.

    Article  PubMed  Google Scholar 

  9. Breslow N, Olshan A, Beckwith JB, Green DM. Epidemiology of Wilms tumor. Med Pediatr Oncol. 1993;21(3):172–81.

    Article  CAS  PubMed  Google Scholar 

  10. Lonergan GJ, Martinez-Leon MI, Agrons GA, Montemarano H, Suarez ES. Nephrogenic rests, nephroblastomatosis, and associated lesions of the kidney. Radiographics. 1998;18(4):947–68.

    Article  CAS  PubMed  Google Scholar 

  11. Lowe LH, Isuani BH, Heller RM, Stein SM, Johnson JE, Navarro OM, et al. Pediatric renal masses: Wilms tumor and beyond. Radiographics. 2000;20(6):1585–603.

    Article  CAS  PubMed  Google Scholar 

  12. Scott RH, Murray A, Baskcomb L, Turnbull C, Loveday C, Al-Saadi R, et al. Stratification of Wilms tumor by genetic and epigenetic analysis. Oncotarget. 2012;3(3):327–35.

    PubMed Central  PubMed  Google Scholar 

  13. Lee SB, Haber DA. Wilms tumor and the WT1 gene. Exp Cell Res. 2001;264(1):74–99.

    Article  CAS  PubMed  Google Scholar 

  14. Coppes MJ, Haber DA, Grundy PE. Genetic events in the development of Wilms’ tumor. N Engl J Med. 1994;331(9):586–90.

    Article  CAS  PubMed  Google Scholar 

  15. Merks JH, Caron HN, Hennekam RC. High incidence of malformation syndromes in a series of 1073 children with cancer. Am J Med Genet A. 2005;134A(2):132–43.

    Article  PubMed  Google Scholar 

  16. Miller RW, Fraumeni JF Jr, Manning MD. Association of Wilms’s tumor with aniridia, hemihypertrophy and other congenital malformations. N Engl J Med. 1964;30(270):922–7.

    Article  Google Scholar 

  17. Beckwith JB, Palmer NF. Histopathology and prognosis of Wilms tumors: results from the First National Wilms’ Tumor Study. Cancer. 1978;41(5):1937–48.

    Article  CAS  PubMed  Google Scholar 

  18. Davenport KP, Blanco FC, Sandler AD. Pediatric malignancies: neuroblastoma, Wilm’s tumor, hepatoblastoma, rhabdomyosarcoma, and sacroccygeal teratoma. Surg Clin North Am. 2012;92(3):745–67.

    Article  PubMed  Google Scholar 

  19. Ng YY, Hall-Craggs MA, Dicks-Mireaux C, Pritchard J. Wilms’ tumour: pre- and post-chemotherapy CT appearances. Clin Radiol. 1991;43(4):255–9.

    Article  CAS  PubMed  Google Scholar 

  20. Khanna G, Rosen N, Anderson JR, Ehrlich PF, Dome JS, Gow KW, et al. Evaluation of diagnostic performance of CT for detection of tumor thrombus in children with Wilms tumor: a report from the Children’s Oncology Group. Pediatr Blood Cancer. 2012;58(4):551–5.

    Article  PubMed Central  PubMed  Google Scholar 

  21. Hamilton TE, Shamberger RC. Wilms tumor: recent advances in clinical care and biology. Semin Pediatr Surg. 2012;21(1):15–20.

    Article  PubMed  Google Scholar 

  22. Príncipios e práticas de oncologia pediátrica 5 ed, Philip A Pizzo e David G. Poplack.

  23. Diagnostic imaging pediatrics—Donnelly.

  24. Leite KRM, Sadi MV. Tumores de células germinativas do testículo. Int Braz J Urol. 2003;29(suppl 1):35–43.

    Google Scholar 

  25. Projeto Diretrizes - Associação Médica Brasileira e Conselho Federal de Medicina - Carcinoma de Células Germinativas do Testículo: Diagnóstico e Estadiamento - Autoria: Sociedade Brasileira de Urologia 3 de dezembro de 2008 - Pompeo ACL, Carrerette FB, Moraes Jr AAG, Vinhaes AFJ, Andrade CAV, Araújo CM, Viégas C, Gouvêa e Silva ECC, Zani EL, Guimarães GC, Loureiro KCF, Rodrigues Netto Jr N, Mattos RM, Zequi SC, Nova TP, Clark O.

  26. Schiavon JLO, Lederman HM. Whole body MRI and diffusion weighed images in pediatric oncology: lymphomas and several others tumors. Curr Radiol Rep. 2014;2(7):1–7.

    Google Scholar 

  27. Schiavon JLO, Pioner GG, Lederman HM. MRI in pediatric oncology, abdominal tumors: diffusion. Curr Radiol Rep. 2014;2(12):1–5.

    Google Scholar 

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Authors and Affiliations

  1. Departamento de Diagnóstico por Imagem – Universidade Federal de Sao Paulo DDI – UNIFESP, São Paulo, Brazil

    Jose Luiz de Oliveira Schiavon, Rodrigo Regacini & Henrique Manoel Lederman

  2. IOP-GRAAC/UNIFESP – Instituto de Oncologia Pediatrica - Universidade Federal de São Paulo, São Paulo, Brazil

    Vivian Siqueira Tostes

Authors
  1. Jose Luiz de Oliveira Schiavon
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  2. Vivian Siqueira Tostes
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  3. Rodrigo Regacini
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  4. Henrique Manoel Lederman
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Corresponding author

Correspondence to Jose Luiz de Oliveira Schiavon.

Additional information

This article is part of the Topical Collection on MRI for Pediatric Oncology.

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de Oliveira Schiavon, J.L., Tostes, V.S., Regacini, R. et al. MRI Evaluation of Pediatric Malignant Abdominal Tumors. Curr Radiol Rep 3, 28 (2015). https://doi.org/10.1007/s40134-015-0111-2

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  • DOI: https://doi.org/10.1007/s40134-015-0111-2

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