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Eosinophilic Esophagitis, Then and Now: A Review

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Abstract

Purpose of Review

In this review, we highlight new advances in diagnostic and therapeutic modalities of eosinophilic esophagitis (EoE) and progress in understanding of its pathophysiology which has led to these advances.

Recent Findings

The new pharmacological and nonpharmacological treatment options have also focused on improving adherence to the treatment. It has made it possible to treat some more resistant pediatric patients with EoE.

Summary

EoE is the result of esophageal dysfunction secondary to inflammatory/immune response of esophagus to certain antigens present in food or environment, which may be known or unknown. Treatment modalities are directed towards elimination of inciting antigen in the form of dietary eliminations, medications with anti-inflammatory or immunomodulatory effects. Recent research data has supported some new dietary approaches and medication for better response to treatment and improved treatment outcome.

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References

Papers of particular interest, published recently, have been highlighted as:  •• Of major importance

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  1. Division of Gastroenterology Hepatology and Nutrition, Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Roopali Mittal

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Mittal, R. Eosinophilic Esophagitis, Then and Now: A Review. Curr Pediatr Rep 11, 233–244 (2023). https://doi.org/10.1007/s40124-023-00309-z

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