Behavioral Therapy Approaches for the Management of Low Back Pain: An Up-To-Date Systematic Review
Low back pain is one of the most common causes for seeking medical treatment and it is estimated that one in two people will experience low back pain at some point during their lifetimes. Management of low back pain includes pharmacological and non-pharmacological approaches. Non-pharmaceutical treatments include interventions such as acupuncture, spinal manipulation, and psychotherapy. The latter is especially important as patients who suffer from low back pain often have impaired quality of life and also suffer from depression. Depressive symptoms can appear because back pain limits patients’ ability to work and engage in their usual social activities. The aim of this systematic review was to overview the behavioral approaches that can be used in the management of patients with low back pain. Approaches such as electromyography (EMG) biofeedback, cognitive behavioral therapy, and mindfulness-based stress reduction are discussed as non-pharmacological options in the management of low back pain.
KeywordsBehavioral Low back Pain Psychotherapy
Low back pain (LBP) is defined as pain and discomfort below the costal margin and above the inferior gluteal folds . It is one of the most common causes for seeking medical treatment and it is estimated that 1 in 2 people will experience low back pain at some point during their lifetimes .
The temporal evolution of symptoms divides low back pain into acute (symptoms lasting < 4 weeks), sub-acute (symptoms lasting 4–12 weeks) or chronic (symptoms lasting at least 3 months). Chronic LBP will affect at least 10% of low back pain sufferers .
Further classification of LBP depends on whether it shows a specific correlation to an underlying pathology. Specific LBP correlates with a local infection, injury, trauma or structural deformity, whereas in non-specific LBP no causal pathology is found. In such cases, factors other than anatomic probably play an important role in generating pain. Such factors include muscle spasms and back strains .
Management of low back pain includes pharmacological  and non-pharmacological approaches. Non-pharmaceutical treatments include interventions such as acupuncture, spinal manipulation, and psychotherapy. The latter is especially important, as patients who suffer from low back pain often suffer from depression  and have impaired quality of life, as they are unable to work and engage in their usual social activities because of their disability.
The aim of this paper was to systematically review the evidence regarding the effectiveness of behavioral approaches in the management of patients with LBP.
Overview of Behavioral Therapy Approaches
Evolution of behavioral psychotherapeutic approaches
Behavioral psychotherapy type
Behavior analysis takes into consideration every behavior, including overt and covert
The therapist focuses on specific learned behaviors and how the environment influences such behaviors
Cognitive behavioral therapy
CBT focuses on the development of individual strategies aimed to solve current problems and to change unhelpful patterns in cognitions (i.e., thoughts and beliefs), behaviors, and emotional regulation
Acceptance and commitment therapy
Dialectical behavioral therapy
Integrative behavioral couples therapy
Cognitive behavioral analysis
Third wave therapies prioritize the holistic promotion of health and well-being and are less focused on reducing psychological and emotional symptoms. These therapies abandon key assumptions associated with traditional cognitive therapy and is informed by emerging research in cognitive psychology and neuroscience. Concepts such as metacognition, acceptance, mindfulness, personal values, and spirituality are frequently incorporated into what might otherwise be considered traditional behavioral interventions
Classic behavioral therapy is considered as the “first wave” of behavioral therapy approaches. This kind of psychotherapy is based on behavioral learning in which the therapist assists the patient to overcome stressful situations by teaching relaxation skills. The therapy aims to reduce maladaptive behaviors and simultaneously encourage the patient to adopt new behaviors that facilitate their day-to-day lives by providing social and problem-solving skills training .
Cognitive behavioral therapy (CBT), the most commonly used and studied type of psychotherapy, represents the second wave of behavioral approaches. CBT focuses on the development of individual strategies aiming to solve current problems and to change unhelpful patterns in cognitions (i.e., thoughts and beliefs), behaviors, and emotional regulation .
CBT can be delivered in different ways: as an individual face-to-face therapy, the success of which relies to a significant degree on the patient—therapist relationship; as a self-administered therapy, which can be done by using materials (i.e., reading books or using the Internet) teaching how to implement CBT without the guidance of a mental health professional ; or as a group treatment. The latter is notable, as it confronts social isolation, which is an important aspect in the case of chronic pain. It is well known that the interaction with other people is a powerful way of creating a shift out of pain pathways leading to decreased pain perception .
Third wave therapies prioritize the holistic promotion of health and well-being and are less focused on reducing psychological and emotional symptoms. These therapies abandon key assumptions associated with traditional cognitive therapy informed by emerging research in cognitive psychology and neuroscience. Concepts such as metacognition, acceptance, mindfulness, personal values, and spirituality are frequently incorporated into what might otherwise be considered traditional behavioral interventions .
Literature Search Strategy
Literature Search Strategy
A systematic computer-based literature search was conducted on February 19, 2018, on PubMed database. For the search we used two Medical Subject Headings (MeSH) terms in either title or abstract. Term A was “low back pain” and Term B was “behavioral therapy” or “behavioral therapy”. We also perused the reference lists of the papers in order to find papers not found through the search strategy.
to be original research (including trials, observational studies, and case series),
to study human adult subjects,
to be in english,
to primarily focus on the effectiveness of behavioral therapy,
to involve patients with low back pain.
Compliance with Ethics Guidelines
This article is based on previously conducted studies and does not involve any new studies of human or animal subjects performed by any of the authors.
Characteristics of the papers included in this review
Year of publication
Number of publications per decade
Number of patients per publication
Type of low back pain
Type of psychotherapy studied
Classic behavioral therapy
Cognitive behavioral therapy
Third wave approaches
Comparing different types
The predominant, purely behavioral, individual approach that has been studied in LBP is biofeedback. Biofeedback is a relaxation technique that focuses on educating patients to alter brain activity, blood pressure, heart rate, and other autonomic nervous system functions that normally are not controlled voluntarily [52, 53].
Electromyography (EMG) biofeedback has been successful in reducing standing levels of paraspinal muscle tension in patients with chronic low back pain ; however studies of EMG-biofeedback in LBP have not provided robust data supporting a direct analgesic effect .
Cognitive Behavioral Therapy
CBT is the most common type of psychotherapy that has been applied in LBP, in adults of all age groups .
Four components summarize the theoretical background of CBT in the management of LBP: (1) the patient’s knowledge and understanding about pain and pain perception, (2) the use of active coping skills, (3) the maintenance of behavioral pain-coping strategies (such as activity pacing and pleasant activity scheduling), and (4) problem-solving methods that enable patients to analyze and develop plans for dealing with pain or other challenging situations .
Cognitive relearning aims to shift attention from incorrect and erratic thoughts and fears to adaptive thought patterns. In patients with LBP, activity pacing and graded exposure to situations that they have previously avoided may lead to increases in the levels of activity . The main assumption is that patients’ thoughts and beliefs about their disease or symptoms will influence their feelings and physiological reactions and consequently their behaviors . Congruently, a strong link between negative beliefs and increased pain perception has been shown in several studies of chronic LBP patients . In addition, chronic LBP can lead to functional alterations in the circuitry underlying the cognitive control of pain . The link between pain-related thought suppression and brain morphology may provide a new perspective on the understanding of the cognitive control of pain in chronic LBP, which may help improve the outcomes of cognitive behavioral therapy .
The Role of Patients’ Expectations
A psychological factor that is an important prognostic determinant in LBP is health locus of control [58, 59]. Health locus of control is defined as patients’ perception of who is responsible for their condition. There are three types of health locus of control: internal (patients believe that they are responsible for their own condition), external (patients believe that others are responsible for their condition), and chance (patients believe that their condition is determined by chance) . People with LBP with higher levels of external locus of control have a poorer prognosis and have greater expectations from treatment. It has been shown that patients’ expectations [32, 34] and patients’ preferences for the type treatment  influence the outcome in patients with chronic LBP.
Patients with an external locus of control have difficulty coping with their symptoms . CBT interventions have the scope to address a patient’s health locus of control perception and coping skills . Adaptive coping, as a personality trait, is associated with better pain-related functioning , and CBT as part of rehabilitation can encourage such beneficial pain coping behavior by altering patients’ pain perception, thereby reducing the adverse effects of pain [20, 38]. Therefore, the modification of patients’ beliefs about the nature and treatment of their pain may be associated with improvements in patients’ perceptions of the level of their disability .
Graded Activity and Exposure
Graded activity and graded exposure incorporate behavioral and cognitive approaches to improve activity tolerance . Such approaches have been tested in both individual [24, 31] and group  sessions.
Individual-graded activity sessions have shown similar effectiveness compared to physiotherapy  and motor control exercises  in patients with chronic nonspecific LBP. In an observational study of patients with chronic LBP, group sessions of graded activity showed significant improvement in pain intensity .
Besides the effect on pain intensity, behavioral-graded activity has also proven to be a successful method of restoring occupational function and facilitating return to work in patients with sub-acute LBP .
In a randomized prospective study, Brox et al. compared focused CBT intervention for physical activation with spine fusion surgery for LBP. CBT had similar effects with fusion surgery, but at 12 months the CBT group showed less fear avoidance . A longer-term follow-up confirmed these findings even at 4-years .
In the majority of the studies, CBT was implemented as part of an add-on multidisciplinary approach [13, 14, 18, 26, 27, 28, 29, 37]. However, the effectiveness of a multidisciplinary approach incorporating CBT in reducing pain intensity compared to standard care remains controversial.
Some studies report significantly greater improvements in mean pain intensity when CBT was used [28, 29]; however in other studies, the multidisciplinary approach had no significant impact on pain management [10, 18, 26, 27, 37, 46]. Moreover, the multidisciplinary rehabilitation program including CBT has been found to be superior to the usual care practice alone. This superiority has been observed in aspects such as reducing disability and kinesiophobia, decatastrophizing [22, 28], and enhancing quality of life of LBP sufferers [22, 27, 37].
Possible explanations about the controversy in these findings include the heterogeneity of the studied populations, the differences between the multidisciplinary approaches and the CBT characteristics per se. It is of interest that there were less psychotherapy sessions (ranging from 3 to 8 sessions) in the studies showing no analgesic effect of CBT compared to those studies where CBT effectively reduced pain intensity (total number of sessions ranged from 10 to 36).
Group-based CBT has been used to address environmental, social, and emotional influences on pain experience, depression, and decreased activity from chronic LBP .
A group-based, multidisciplinary, cognitive behavioral rehabilitation program was found to be superior to traditional exercises in reducing pain and kinesiophobia, decatastrophizing, and enhancing quality of life of subjects with chronic LBP, with the effects lasting for at least 2 years after the end of the intervention . However, small-group CBT showed similar effects with no significant differences either post-treatment or at 6-month follow-up, when compared to EMG biofeedback .
Outpatient group CBT, based on the negative reinforcement of pain behaviors, effectively reduced pain intensity for up to 12 months post treatment. When combined with aerobic exercise, pain intensity was shown to improve sooner .
CBT in Acute LNP
Catastrophic thinking and fear-avoidance beliefs can negatively influence severe acute pain following surgical operation, which can lead to delayed ambulation and discharge . Preoperative CBT appears to facilitate mobility in the acute post-surgical phase; despite high levels of acute post-surgical pain reported by patients, there was a slightly lower intake of rescue painkillers in the CBT group. This evidence may suggest an overall improved ability to cope with pain post-surgically following pre-operative CBT intervention in patients with acute LBP .
In an interesting study comparing individual CBT and EMG biofeedback in patients with acute LBP, Hasenbring et al. showed that both techniques are effective; however CBT was superior to EMG biofeedback intervention in pain relief . Overall, individually scheduled, risk factor-based CBT could be a beneficial treatment modality that can be offered, in addition to medical treatment, as it may be an effective way to prevent chronification in these patients .
Other Forms of CBT
Additional Effects of CBT in the Management of LBP
CBT can also target other symptoms in addition to pain in patients with LBP. For example, poor sleep quality is common in LBP patients; however, it is still debatable whether lack of sleep exacerbates pain or whether pain prevents sleep . One study showed that poor sleep is a better predictor of disability than the actual severity of pain . Insomnia-focused CBT is an example of a problem-focused therapy intended to improve the quality of sleep .
Similarly, depression and stress augment perception of pain [66, 67]. Targeting anxiety and depression can therefore indirectly decrease pain perception. Furthermore, working on pain de-catastrophizing through CBT sessions can help patients regain their functionality .
Third Wave Approaches
Mindfulness-Based Stress Reduction
Mindfulness is a fundamental construct in the practice of Buddhist meditation but has also been described as a specific state of consciousness. This state is defined as a non- elaborative, non-judgmental, moment-to-moment awareness or an ability to trust one’s own experience .
Mindfulness-based stress reduction (MBSR) is the most common mindfulness-based intervention. Methods of this practice include sitting and walking meditation, yoga, and body scan, a sustained mindfulness practice that promotes greater awareness of the body by sequential focus on different parts of the body .
LBP patients have shown promising results in mindfulness-based meditation programs [17, 48, 49, 50]. Supplementary therapy with MBSR rather than usual care alone can result in greater improvement in back pain and functional limitations [15, 23]. Mindfulness-based interventions are also feasible, acceptable, and safe in opioid-treated chronic LBP [19, 51]. Based on this evidence and the successful use of this type of intervention in older adults [49, 50], mindfulness-based interventions provide a valuable approach to pain management that is applicable to the whole spectrum of patients with LBP.
Acceptance and Commitment Therapy (ACT)
The acceptance and commitment therapy (ACT) targets ineffective pain control strategies and experiential avoidance . Using ACT, patients learn how to accept unpleasant feelings, sensations, and thoughts. Although negative pain-associated thoughts are targeted, there is no effort to change their irrational content in this form of therapy . Developing mindfulness is one of the fundamental strategies in ACT along with value clarification and developing the patients’ ability to commit to these values in their daily lives.
Pain reduction is not the target of acceptance-based therapies. Participants learn to let go of ineffective pain control strategies and work with the therapist on how to accept pain. Therefore, whether pain intensity is an appropriate outcome measure for acceptance-based interventions in chronic pain patients remains debatable. Upcoming research should not only rely on pain intensity as an outcome but also include other parameters such as interference of pain with daily life .
Studies of ACT in LBP are lacking. Currently, a randomized controlled trial of physiotherapy informed by acceptance and commitment therapy (PACT) versus usual physiotherapy for adults with chronic LBP is underway .
Contextual Cognitive Behavioral Therapy
Contextual cognitive behavioral therapy (CCBT) is a treatment approach that has also been tried in LBP, and combines CBT with ACT . The content of each session in CCBT is not structured and the specific features of CCBT deemed appropriate for each patient are at the discretion of the therapist. For example, the first session is dedicated to building a good relationship with patients and determining the expectations about the content and the rationale of subsequent sessions. Subsequent sessions include a mixture of techniques based on enhancing acceptance through experiential, exposure-based and mindfulness-based methods using present moment focus and directed awareness .
Conclusions and Future Directions
Behavioral therapy approaches are effective in patients with LBP particularly in altering pain perception and helping patients to regain their functionality.
A multidisciplinary approach is the future. Multidisciplinary rehabilitation includes more than just physical treatment. A team approach accounting for several aspects within the bio-psychosocial model is more likely to help individuals with chronic LBP compared to standard care alone.
CBT is the type of psychotherapy that has been most studied in patients with LBP. Although most of the other behavioral therapy interventions have been tried in randomized trials in other conditions, more trials of such approaches are needed in patients with LBP.
Future research, however, must focus on the improvement of specific outcomes, using not only measures of pain intensity but also using measures of pain acceptance, reduction of medication used, disability, and quality of life to assess efficacy. Also, a comparison of the effectiveness of the different psychotherapy approaches on the different outcomes is important to tailor the therapeutic approach to a patient’s specific needs.
This is a summary of independent research carried out at the NIHR Sheffield Biomedical Research Centre (Translational Neuroscience). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health. Dr. Zis is sincerely thankful to the Ryder Briggs Fund.
No funding or sponsorship was received for this study or publication of this article.
All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval for the version to be published.
Kristallia Vitoula, Annalena Venneri, Giustino Varrassi, Antonella Paladini, Panagiota Sykioti, Joy Adewusi, and Panagiotis Zis have nothing to disclose.
Compliance with Ethics Guidelines
This article is based on previously conducted studies and does not involve any new studies of human or animal subjects performed by any of the authors.
The datasets during and/or analyzed during the current study are available from the corresponding author on reasonable request.
This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
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