|
Median age (IQR)
|
57.0 (44.0–64.0)
|
57.0 (46.0–65.0)
|
43.5 (32.5–58.0)
|
–
|
0.001
|
|
Age, years
| | | | |
< 0.001
|
|
< 40
|
77 (21.6)
|
60 (18.7)
|
17 (47.2)
|
22.1
| |
|
41–60
|
147 (41.2)
|
135 (42.1)
|
12 (33.3)
|
8.1
| |
|
> 60
|
133 (37.3)
|
126 (39.3)
|
7 (19.4)
|
5.3
| |
|
Male gender
|
188 (52.7)
|
172 (53.6)
|
16 (44.4)
|
8.5 (male), 11.8 (female)
|
0.298
|
|
Underlying hematologic disease
| | | | |
< 0.001
|
|
Allogeneic HSCT
|
21 (5.9)
|
19 (5.9)
|
2 (5.6)
|
9.5
| |
|
Acute myeloid leukemia
|
60 (16.8)
|
40 (12.5)
|
20 (55.6)
|
33.3
| |
|
Acute lymphoblastic leukemia
|
28 (7.8)
|
24 (7.5)
|
4 (11.1)
|
14.3
| |
|
Chronic lymphocytic leukemia
|
9 (2.5)
|
8 (2.5)
|
1 (2.8)
|
11.1
| |
|
Non-Hodgkin’s lymphoma
|
161 (45.1)
|
156 (48.6)
|
5 (13.9)
|
3.1
| |
|
Myelodysplastic syndrome
|
13 (3.6)
|
12 (3.7)
|
1 (2.8)
|
7.7
| |
|
Severe aplastic anemia
|
4 (1.1)
|
3 (0.9)
|
1 (2.8)
|
25.0
| |
|
Multiple myeloma
|
60 (16.8)
|
59 (18.4)
|
1 (2.8)
|
1.7
| |
|
Severe GVHD after HSCT
|
1 (0.3)
|
0 (0)
|
1 (2.8)
|
100.0
| |
|
Other underlying disease
|
|
Diabetes mellitus
|
28 (14.8)
|
26 (17.0)
|
2 (5.6)
|
7.1
|
0.082
|
|
HIV
|
8 (2.3)
|
8 (2.5)
|
0 (0)
|
0
|
1.000
|