Biogenic titanium nanoparticles (TiO2NPs) from Tricoderma citrinoviride extract: synthesis, characterization and antibacterial activity against extremely drug-resistant Pseudomonas aeruginosa

International Nano Letters volume 11, pages35–42(2021)Cite this article

Abstract

Green synthesis of nanoparticles has attracted significant attention as an alternative to chemical synthesis procedure. The bulk availability of plants, microbial biomass and the use of eco-friendly solvents has significantly reduced the cost in addition to the hazards associated with the chemical synthesis of the nanoparticle. In this study, we demonstrated the biosynthesis of titanium nanoparticles (TiO2NPs) with the extract of Trichoderma citrinoviridae as a reducing agent. The physicochemical properties of biogenic TiO2NPs were studied using FESEM, Zeta sizer, FTIR and XRD. The size (10–400 nm), morphology, crystallinity, zeta potential (29.5 mV), and polydispersity index (0.327) suggested that the biogenic TiO2NPs were polymorphic, crystalline and stable. FESEM revealed that the synthesized TiO2NPs were majorly irregular, and some interesting TiO2NPs structures, i.e., triangular, pentagonal, spherical and rod were also observed. The biogenic TiO2NPs showed excellent antibacterial activity (100 µg/mL) against planktonic cells of extremely drug-resistant (XDR) Pseudomonas aeruginosa clinical isolates. The TiO2NPs also had better antioxidant potential as compared to standard gallic acid. This study indicates the use of T. citrinoviridae for synthesizing biogenic TiO2NPs and their potential use against XDR bacteria.

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Acknowledgment

The authors thank Dr. Renu Bharadwaj, Head of Department, Microbiology, B. J. Govt. Medical College, Pune – 411001, India for providing P. aeruginosa clinical isolates.

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Affiliations

  1. Center for Innovation Research and Consultancy, Pune, 411018, India

    Sagar Arya

  2. Department of Botany, Prof. Ramkrishna More College of Arts, Commerce and Science, Akurdi, Pune, 411044, India

    Hiralal Sonawane & Siddharam Math

  3. Department of Physics, Prof. Ramkrishna More College of Arts, Commerce and Science, Akurdi, Pune, 411044, India

    Popat Tambade

  4. Department of Chemistry, Prof. Ramkrishna More College of Arts, Commerce and Science, Akurdi, Pune, 411044, India

    Manohar Chaskar & Dnyaneshwar Shinde

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  1. Sagar Arya
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  2. Hiralal Sonawane
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Correspondence to Sagar Arya or Hiralal Sonawane.

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Arya, S., Sonawane, H., Math, S. et al. Biogenic titanium nanoparticles (TiO2NPs) from Tricoderma citrinoviride extract: synthesis, characterization and antibacterial activity against extremely drug-resistant Pseudomonas aeruginosa. Int Nano Lett 11, 35–42 (2021). https://doi.org/10.1007/s40089-020-00320-y

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Keywords

  • Trichoderma citrinoviridae
  • Titanium nanoparticles
  • TiO2NPs
  • Pseudomonas aeruginosa
  • Antibacterial activity
  • Antioxidant activity