Feasibility study of radiophotoluminescent glass dosimeter for in vivo dosimetry in external photon beam radiotherapy


The purpose of this study was to check the applicability of radiophotoluminescent glass dosimeter (RPLGD) for in vivo dosimetry in external photon beams radiotherapy. The entrance dose measurements were performed. The influence of beam set-up parameters on the entrance dose was investigated using the RPLGDs. In this study, the RPLGD and 6-MV photon beam produced by a linear accelerator were used. The entrance dose calibration factors of the RPLGDs and beam energy and geometry-dependent correction factors were measured using a water phantom. For a correction factor related to the irradiation set-up, Monte Carlo (MC) simulation was performed. The entrance dose verification was performed on an Alderson Rando phantom during 64 single beam irradiations using different beam set-up. One RPLGD was attached on surface during a single beam irradiation for delivery of clinically planned dose. Additionally, during 50 irradiations, one RPLGD was placed directly inside the Alderson Rando phantom at different points in the beam path to verify the dose delivery. The mean ratio of the measured entrance dose using RPLGD on the surface of the phantom to the expected dose which was calculated by treatment planning system was equal to 1.001 ± 0.030. The mean ratio of the dose measured using RPLGDs inside the Alderson Rando phantom to the expected dose was equal to 1.019 ± 0.019. This study concludes that the RPLGD is suitable for in vivo dosimetry in external photon beam radiotherapy for dose verification within ± 5% at the clinically acceptable level.

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The present work has been supported by the Korea Research Institute of Standards and Science (KRISS) under the project ‘Development of Measurement Standards for Medical Radiation,’ by the research project No. 2015M2C5A1041690 ‘Establishment of Measurement Standards for Testing of Radiation Devices’ granted by the Ministry of Science and ICT (MOST) and by Chungnam National University Hospital Research Fund, 2017.

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Correspondence to Chul-Young Yi or Ki-Hwan Kim.

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Shehzadi, N.N., Yi, CY., Kim, KH. et al. Feasibility study of radiophotoluminescent glass dosimeter for in vivo dosimetry in external photon beam radiotherapy. J. Korean Phys. Soc. 78, 523–534 (2021). https://doi.org/10.1007/s40042-021-00092-4

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  • In vivo dosimetry
  • Entrance dose
  • Radiophotoluminescent glass dosimeter
  • External beam radiotherapy
  • Quality assurance in radiotherapy