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An Analysis on the Association Between ABO and Rh Blood Groups with Obesity

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Proceedings of the National Academy of Sciences, India Section B: Biological Sciences Aims and scope Submit manuscript

Abstract

Overweight or obesity is a global and severe healthcare problem associated with many diseases. The rapid increase in the incidence of obesity all over the world devoted the researchers to analyze the parameters associated with obesity and overweight. The aim of the present study was to detect whether any connection exists between the ABO and Rh blood groups and obesity through statistical methods. Body length and body weight measurements of 306 female participants who referred to Sports Physiology and Blood Bank departments of Pendik Training and Research Hospital within Marmara University were obtained. Blood samples were also collected from each participant, and body mass index [BMI], ABO blood group and Rh blood groups were detected. The association of obesity with blood group and Rh blood group types was analyzed by statistical methods. Age, body weight, BMI, fat percentage, fat weight and muscle weight parameters of the participants were found statistically significant. In the logistic regression analysis conducted to detect the effect of ABO and Rh blood groups on obesity, a statistically significant association was found between ABO blood groups and obesity whereas a considerable association was also detected between Rh blood group and obesity. The authors found that the highest rate of the obese individuals was in A and Rh positive blood groups.

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References

  1. Physical status: the use and interpretation of anthropometry (1995) Report of a WHO Expert Committee World Health Organization technical report series, vol 854, pp 1–452

  2. Kopelman PG (2000) Obesity as a medical problem. Nature 404:635–643

    Article  CAS  PubMed  Google Scholar 

  3. Rayner G, Lang T (2009) Obesity: using the ecologic public health approach to overcome policy cacophony. In: Copelman PG (ed) Clinical obesity in adults and children. Wiley-Blackwell, Malden, pp 452–70

    Google Scholar 

  4. Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C et al (2014) Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 30:766–781

    Article  Google Scholar 

  5. Morrill AC, Chinn CD (2004) The obesity epidemic in the United States. J Public Health Policy 25:353–366

    Article  PubMed  Google Scholar 

  6. Coon JS, Weinstein RS (1986) Blood groups-related antigens as markers of malignant potential heterogeneity in human carcinomas. Hum Pathol 17:1089–1186

    Article  CAS  PubMed  Google Scholar 

  7. Nemesure B, Wu SY, Hennis A, Leske MC (2006) Barbados Eye Study Group. Hypertension, type 2 diabetes, and blood group in population of African ancestry. Ethn Dis 16:822–829

    PubMed  Google Scholar 

  8. Knowles SM (2001) Blood cell antigens and antibodies: erythrocytes, platelets and granulocytes. In: Lewis SM, Bain BJ, Bates I (eds) Dacie and Lewis practical haematology, 9th edn. Churchill Livingstone, London, pp 429–469

    Google Scholar 

  9. Sloan SR, Benjamin RJ, Friedmanlain DF, Webb J, Silberstein L (2003) Transfusion medicine. In: Nathan DG, Ginsburg D, Orkin SH, Look AT (eds) Nathan and Oski’s hematology of ınfancy and childhood, 6th edn. Saunders, Philadelphia, pp 1709–1756

    Google Scholar 

  10. Reid ME, Calhoun L, Petz LD (2006) Erythrocyte antigens and antibodies. In: Lichtman MA, Beutler E, Coller BS, Kipps TJ, Seligsohn U (eds) Williams hematology, 7th edn. McGraw-Hill, New York, pp 2119–2136

    Google Scholar 

  11. Clarck P, Wu O (2011) ABO blood group and thrombosis: a casual association, but is there value in screening? Future Cardiol 7:191–201

    Article  CAS  Google Scholar 

  12. Sari I, Ozer O, Davutoglu V, Gorgulu S, Eren M, Aksoy M (2008) ABO blood groups distribution and major cardiovascular risk factors in patients with acute myocardial infarction. Blood Coagul Fibrinolysis 19:231–234

    Article  PubMed  Google Scholar 

  13. Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M et al (2010) Risk of gastric cancer and peptic ulcers in relation to ABO blood type: a cohort study. Am J Epidemiol 172:1280–1285

    Article  PubMed  Google Scholar 

  14. Mandato VD, Torricelli F, Mastrofilippo V, Ciarlini G, Pirillo D, Farnetti E et al (2017) Prognostic impact of ABO blood group on type I endometrial cancer patients-results from our own and other studies. J Cancer 23:2828–2835

    Article  CAS  Google Scholar 

  15. Nakao M, Matsuo K, Hosono S, Ogata S, Ito H, Watanabe M et al (2011) ABO blood group alleles and the risk of pancreatic cancer in a Japanese population. Cancer Sci 102:1076–1080

    Article  CAS  PubMed  Google Scholar 

  16. Jafari E, Sebghatollahi V, Kolahdoozan S, Elahi E, Pourshams A (2012) Body mass index and ABO blood group among different ethnicities of the Golestan Cohort study subjects. Govaresh 17:50–54

    Google Scholar 

  17. Chandra T, Gupta A (2012) Association and distribution of hypertension, obesity and ABO blood group in blood donors. Iran J Pediatr Hematol Oncol 2:140–145

    Google Scholar 

  18. Aboel-Fetoh NM, Alanazi AR, Alanazi AS, Alruwili AN (2016) ABO blood group and risk for obesity in Arar, Northern Saudi Arabia. J Egypt Public Health Assoc 91:169–173

    PubMed  Google Scholar 

  19. Slipko Z, Latuchowska B, Wojtkowska E (1994) Body structure and ABO and Rh blood groups blood group in patients with advanced coronary heart disease after aortocoronary by-pass surgery. Pol Arch Med Wewn 91:55–60

    CAS  PubMed  Google Scholar 

  20. Mascie-Taylor CG, Lasker GW (1990) Lack of an association between ABO and Rh blood groups blood groups polymorphisms and stature, body weight, and BMI in a cohort of British women. Hum Biol 62:573–576

    CAS  PubMed  Google Scholar 

  21. Gates MA, Wolpin BM, Cramer DW, Hankinson SE, Tworoger SS (2011) ABO blood groups and incidence of epithelial ovarian cancer. Int J Cancer 128:482–486

    Article  CAS  PubMed  Google Scholar 

  22. Sukalingam K, Ganesan K (2015) Rh blood groupsesus blood group associated with risk to obesity and diabetes mellitus: a report on Punjabi population in Selangor, Malaysia. Int J Integr Med Sci 2:105–109

    Google Scholar 

  23. Nas S, Fışkın R (2017) A research on relationship between ABO blood group and body mass index among Turkish seafarers. Int Marit Health 68:140–146

    Article  PubMed  Google Scholar 

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Acknowledgements

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Authors and Affiliations

  1. Department of Microbiology and Blood Bank, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey

    Canan Eren

  2. Department of Sports Physiology, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey

    Serpil Çeçen

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  1. Canan Eren
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  2. Serpil Çeçen
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Correspondence to Canan Eren.

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The authors declare no conflict of interest to publish this manuscript.

Additional information

Significance Statement Obesity is a common condition worldwide and a serious global epidemic posing significant threat to human health. Obesity usually reflects complex interactions of genetic, metabolic, environmental, socioeconomic and behavioral factors. The rapid increase in the incidence of obesity devoted the researchers to analyze the parameters associated with obesity and overweight.

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Eren, C., Çeçen, S. An Analysis on the Association Between ABO and Rh Blood Groups with Obesity. Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci. 89, 1095–1100 (2019). https://doi.org/10.1007/s40011-018-1029-2

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  • DOI: https://doi.org/10.1007/s40011-018-1029-2

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