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Thermal and Crystallographic Studies of 1-(2-Fluoro-4-Nitrophenyl)-4-(Prop-2-yn-1-yl)Piperazine Single Crystal

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Abstract

1-(2-Fluoro-4-nitrophenyl)-4-(prop-2-yn-1-yl)piperazine was synthesized and single crystals were grown successfully by slow evaporation solution growth technique at room temperature. The compound was characterized by FTIR, 1H NMR and 13C NMR. From X-ray crystallography the crystal structure is monoclinic having a space group P21/c and the corresponding lattice parameters, a = 9.7366(8) Å, b = 17.9148(13) Å, c = 7.5270(6) Å and β = 102.397 (8)°. Packing studies of compound reveal the presence of several intermolecular interactions viz., C–H···O hydrogen bonding, C(aryl)–H···π interactions and stacking interactions of aromatic rings which stabilize the crystal lattice. The thermal stability of single crystal was determined by TG–DTA and DSC.

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Acknowledgments

Satish Kumar Awasthi is thankful to University of Delhi for financial assistance and University Scientific Instrumentation Center (USIC), University of Delhi, Delhi 110007, Delhi India for analytical data. Chiranjeev Sharma is thankful to UGC for providing SRF. Gunjan Pandey is thankful, to UGC for providing JRF.

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  1. Chemical Biology Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007, India

    Satish Kumar Awasthi, Chiranjeev Sharma, Monika Yadav & Gunjan Pandey

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  1. Satish Kumar Awasthi
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  2. Chiranjeev Sharma
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Correspondence to Satish Kumar Awasthi.

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Awasthi, S.K., Sharma, C., Yadav, M. et al. Thermal and Crystallographic Studies of 1-(2-Fluoro-4-Nitrophenyl)-4-(Prop-2-yn-1-yl)Piperazine Single Crystal. Proc. Natl. Acad. Sci., India, Sect. A Phys. Sci. 84, 19–25 (2014). https://doi.org/10.1007/s40010-013-0102-8

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