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Sulphur Dioxide Induced Alterations in Glycogen Metabolism in Rattus norvegicus

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Abstract

Present study has been undertaken with an aim to assess the effect of sulphur dioxide exposure on the glycogen metabolic pathway of albino rat, Rattus norvegicus. Animal was exposed to two different doses of SO2 (60 and 120 ppm) for two different intervals. The exposure caused significant reduction in the level of glycogen content and significant changes were observed in the activity of glycogen metabolic enzymes in liver of albino rats. Activity of glycogen synthase shows a marked reduction, whereas a significant and prominent enhancement was recorded in the activity of glycogen phosphorylase and glucose-6-phosphatase. From the present findings it can be concluded that SO2 altered the glycogen metabolism in rats.

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Acknowledgment

The authors express their gratitude to Head, Department of Zoology, for providing Central Instrumentation Facility developed with the financial assistance from UGC-SAP and DST-FIST for carrying out this work.

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Authors and Affiliations

  1. Biochemistry Laboratory, Department of Zoology, University of Allahabad, Allahabad, 211002, India

    Firdaus Fatma, Nighat Begum & Ravi S. Pandey

Authors
  1. Firdaus Fatma
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  2. Nighat Begum
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  3. Ravi S. Pandey
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Correspondence to Ravi S. Pandey.

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Fatma, F., Begum, N. & Pandey, R.S. Sulphur Dioxide Induced Alterations in Glycogen Metabolism in Rattus norvegicus . Natl. Acad. Sci. Lett. 38, 311–313 (2015). https://doi.org/10.1007/s40009-014-0323-7

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  • DOI: https://doi.org/10.1007/s40009-014-0323-7

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