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Naive and memory B cells in T-cell-dependent and T-independent responses

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Abstract

This review focuses on the properties and roles of distinct subsets among the primary and the memory B lymphocytes regarding their contribution to helper-T-cell-dependent and -independent antibody responses. The naive/memory B cell functions are explained in the context of current concepts on the basic mechanisms of humoral immunity. Differences between murine and human B cells are also discussed.

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  1. Division of Hematology, Geneva University Hospital, 1211, Geneva 14, Switzerland

    Rudolf H. Zubler

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Zubler, R.H. Naive and memory B cells in T-cell-dependent and T-independent responses. Springer Semin Immunopathol 23, 405–419 (2001). https://doi.org/10.1007/s281-001-8167-7

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