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Typ-2-Diabetes-Prävention und -Remission

Wie rückt man dem Zucker ohne Medikamente zu Leibe?

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Info Diabetologie Aims and scope

Auch wenn in wissenschaftlichen Leitlinien zu Typ-2-Diabetes eine nicht medikamentöse Therapie als Basis vorgesehen ist, steht sie in der klinischen Praxis zunehmend im Schatten der medikamentösen Optionen. In aktuellen Studien widmete man sich den Lebensstilstrategien und die Ergebnisse unterstreichen, dass sich diese Entwicklung umkehren sollte.

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Literatur zum Beitrag Diabetesprävention und -remission

  1. Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R. Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia. 2011 Oct;54(10):2506–14.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Steven S, Hollingsworth KG, Al-Mrabeh A, Avery L, Aribisala B, Caslake M, Taylor R. Very Low-Calorie Diet and 6 Months of Weight Stability in Type 2 Diabetes: Pathophysiological Changes in Responders and Nonresponders. Diabetes Care. 2016; 39: 808–15.

    Article  CAS  PubMed  Google Scholar 

  3. Leslie WS, Ford I, Sattar N, Hollingsworth KG, Adamson A, Sniehotta FF, McCombie L, Brosnahan N, Ross H, Mathers JC, Peters C, Thom G, Barnes A, Kean S, McIlvenna Y, Rodrigues A, Rehackova L, Zhyzhneuskaya S, Taylor R, Lean ME. The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial. BMC Fam Pract. 2016 Feb 16;17:20. doi: 10.1186/s12875-016-0406-2

    Article  PubMed  PubMed Central  Google Scholar 

  4. Taylor R, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, Sattar N, Welsh P, Peters C, Zhyzhneuskaya S, Hollingsworth KG, Al-Mrabeh A, Rodrigues AM, Rehackova L, Adamson AJ, Sniehotta FF, Mathers JC, Ross HM, McIlvenna Y, Kean S, Ford I, McConnachie A, Lean MEJ. Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort. Diabetologia. 2017 Nov 30. doi: 10.1007/s00125-017-4503-0. [Epub ahead of print]

  5. Lean ME, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, Peters C, Zhyzhneuskaya S, Al-Mrabeh A, Hollingsworth KG, Rodrigues AM, Rehackova L, Adamson AJ, Sniehotta FF, Mathers JC, Ross HM, McIlvenna Y, Stefanetti R, Trenell M, Welsh P, Kean S, Ford I, McConnachie A, Sattar N, Taylor R. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet. 201 Dec 4. pii: S0140-6736(17)33102-1. doi: 10.1016/S0140-6736(17)33102-1.

  6. Uusitupa M. Remission of type 2 diabetes: mission not impossible. Lancet. 2018 Feb 10;391(10120):515-516. doi: 10.1016/S0140-6736(17)33100-8. Epub 2017 Dec 5.

  7. Kempf K, Altpeter B, Berger J, Reuß O, Fuchs M, Schneider M, Gärtner B, Niedermeier K, Martin S. Efficacy of the Telemedical Lifestyle intervention Program TeLiPro in Advanced Stages of Type 2 Diabetes: A Randomized Controlled Trial. Diabetes Care. 2017 Jul;40(7):863–871.

    Article  PubMed  Google Scholar 

  8. Sarathi V, Kolly A, Chaithanya HB, Dwarakanath CS. High rates of diabetes reversal in newly diagnosed Asian Indian young adults with type 2 diabetes mellitus with intensive lifestyle therapy. J Nat Sci Biol Med. 2017 Jan-Jun;8(1):60–63. doi: 10.4103/0976-9668.198343.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Johansen MY, MacDonald CS, Hansen KB, Karstoft K, Christensen R, Pedersen M, Hansen LS, Zacho M, Wedell-Neergaard AS, Nielsen ST, Iepsen UW, Langberg H, Vaag AA, Pedersen BK, Ried-Larsen M. Effect of an Intensive Lifestyle Intervention on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial. JAMA. 2017 Aug 15;318(7):637–646.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Balducci S, D’Errico V, Haxhi J, Sacchetti M, Orlando G, Cardelli P, Vitale M, Bollanti L, Conti F, Zanuso S, Nicolucci A, Pugliese G; Italian Diabetes and Exercise Study 2 (IDES_2) Investigators.Effect of a Behavioral Intervention Strategy for Adoption and Maintenance of a Physically Active Lifestyle: The Italian Diabetes and Exercise Study 2 (IDES_2): A Randomized Controlled Trial. Diabetes Care. 2017 Nov;40(11):1444–1452. doi: 10.2337/dc17-0594. Epub 2017 Aug 18.

    Article  PubMed  Google Scholar 

  11. Saslow LR, Daubenmier JJ, Moskowitz JT, Kim S, Murphy EJ, Phinney SD, Ploutz-Snyder R, Goldman V, Cox RM, Mason AE, Moran P, Hecht FM. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. Nutr Diabetes. 2017 Dec 21;7(12):304. doi: 10.1038/s41387-017-0006-9.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Shukla AP, Andono J, Touhamy SH, Casper A, Iliescu RG, Mauer E, Shan Zhu Y, Ludwig DS, Aronne LJ. Carbohydrate-last meal pattern lowers postprandial glucose and insulin excursions in type 2 diabetes. BMJ Open Diabetes Res Care. 2017 Sep 14;5(1):e000440. doi: 10.1136/bmjdrc-2017-000440. eCollection 2017.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Piper C, Marossy A, Griffiths Z, Adegboye A. Evaluation of a type 2 diabetes prevention program using a commercial weight management provider for non-diabetic hyperglycemic patients referred by primary care in the UK. BMJ Open Diabetes Res Care. 2017 Oct 16;5(1):e000418. doi: 10.1136/bmjdrc-2017-000418. eCollection 2017.

    Article  PubMed  PubMed Central  Google Scholar 

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Martin, S. Wie rückt man dem Zucker ohne Medikamente zu Leibe?. Info Diabetol 12, 36–42 (2018). https://doi.org/10.1007/s15034-018-1311-7

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