Für die Behandlung von Patienten mit Lungenkarzinom gab es auch beim ASCO-Kongress 2019 wieder neue Entwicklungen, vor allem beim metastasierten nichtkleinzelligen Lungenkarzinom (NSCLC) und beim lokal begrenzten und lokal fortgeschrittenen NSCLC. Checkpointinhibitoren und auf onkogene Alterationen gerichtete Therapien treiben dabei die Entwicklung in der thorakalen Onkologie.
Literatur
Socinski MA, Jotte RM, Cappuzzo F et al. Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC. N Engl J Med. 2018;378(24):2288–301
Ardizzoni A, Hansen H, Dombernowsky P et al. Topotecan, a new active drug in the second-line treatment of small-cell lung cancer: a phase II study in patients with refractory and sensitive disease. The European Organization for Research and Treatment of Cancer Early Clinical Studies Group and New Drug Development Office, and the Lung Cancer Cooperative Group. J Clin Oncol. 1997;15(5):2090–6
von Pawel J, Schiller JH, Shepherd FA et al. Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer. J Clin Oncol. 1999;17(2):658–67
von Pawel J, Jotte R, Spigel DR et al. Randomized phase III trial of amrubicin versus topotecan as second-line treatment for patients with small-cell lung cancer. J Clin Oncol. 2014;32(35):4012–9
Reck M, Vicente D, Ciuleanu T et al. Efficacy and safety of nivolumab (nivo) monotherapy versus chemotherapy (chemo) in recurrent small cell lung cancer (SCLC): Results from CheckMate 331 Ann Oncol. 2018;29(suppl 10):x39–x43
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hammerschmidt, S., Geßner, C. Immuntherapie bei Lungenkrebs. Pneumo News 11, 41–43 (2019). https://doi.org/10.1007/s15033-019-1249-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s15033-019-1249-z