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CETP-Hemmer senkt Risiko für Herzinfarkte

  • Medizin aktuell
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CardioVasc Aims and scope

Mit dem Wirkstoff Anacetrapib ist erstmals in einer großen Studie bewiesen worden, dass sich auch durch CETP-Hemmung das Risiko für kardiovaskuläre Ereignisse senken lässt. Haupteffekt war dabei eine Reduktion von Herzinfarkten, die Mortalität blieb unverändert.

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Quelle

  • Hot Line — Late Breaking Clinical Trials 4 „Clinical effects of anacetrapib in people with established vascular disease: Results of the Randomized EValuation of the Effects of Anacetrapib through Lipid-modification (HPS3/TIMI55-REVEAL) trial“, ESC-Kongress, 28.8.2017 in Barcelona

  • The HPS3-TIMI55-REVEAL Collaborative Group. Effects of anacetrapib in patients with atherosclerotic vascular disease (REVEAL). N Engl J Med. 2017; https://doi.org/10.1056/NEJMoa1706444

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Overbeck, P. CETP-Hemmer senkt Risiko für Herzinfarkte. CV 17, 15–16 (2017). https://doi.org/10.1007/s15027-017-1166-1

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  • DOI: https://doi.org/10.1007/s15027-017-1166-1

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