Zusammenfassung
Der Multikinaseinhibitor Sorafenib ist die einzige zugelassene, systemisch wirksame Substanz bei fortgeschrittenem hepatozellulärem Karzinom. Neue molekulare Therapien sind in der klinischen Entwicklung, bisher aber mit meist negativen Ergebnissen. Es gilt nun, prognostische und prädiktive Faktoren für eine personalisierte Therapie zu identifizieren.
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Interessenkonflikt
Prof. Dr. Arndt Vogel gibt Zusammenarbeit in HCC-Studien mit und Beratungs- sowie Vortragstätigkeit für Bayer und Lilly an. Dr. Nora Schweitzer erklärt, keine Interessenkonflikte zu haben.
Der Verlag erklärt, dass die inhaltliche Qualität des Beitrags von zwei unabhängigen Gutachtern geprüft wurde. Werbung in dieser Zeitschriftenausgabe hat keinen Bezug zur CME-Fortbildung. Der Verlag garantiert, dass die CME-Fortbildung sowie die CME-Fragen frei sind von werblichen Aussagen und keinerlei Produktempfehlungen enthalten. Dies gilt insbesondere für Präparate, die zur Therapie des dargestellten Krankheits bildes geeignet sind.
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Schweitzer, N., Vogel, A. Systemische Therapie des hepatozellulären Karzinoms. Im Focus Onkologie 17, 40–49 (2014). https://doi.org/10.1007/s15015-014-0006-8
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DOI: https://doi.org/10.1007/s15015-014-0006-8