Skip to main content
SpringerLink
Log in

Lichen sclerosus im Kindesalter

Eine therapeutische Herausforderung

  • Fortbildung
  • Published:
Pädiatrie Aims and scope

Lichen sclerosus im Kindesalter ist keine seltene Erkrankung. Eine frühe Diagnosestellung und ein zügiger Therapiebeginn sind nicht nur zur Vermeidung von Komplikationen, sondern auch zur Verbesserung der Lebensqualität von entscheidender Bedeutung.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1
Abb. 2

Literatur

  1. Goldstein AT et al. Prevalence of vulvar lichen sclerosus in a general gynecology practice. J ReprodMed 2005;50:477–80

    Google Scholar 

  2. Powell J, Wojnarowska F. Childhood vulvar lichen sclerosus. The course after puberty. J Reprod Med 2002;47:706–9

    PubMed  Google Scholar 

  3. Smith YR, Haefner HK. Vulvar lichen sclerosus: pathophysiology and treatment. Am J Clin Dermatol 2004;5:105–25

    Article  PubMed  Google Scholar 

  4. Lewis FM SS et al. British Association of Dermatologists guidelines for the management of lichen sclerosus 2018. Br J Dermatol 2018;178(4):839–53

    Article  CAS  PubMed  Google Scholar 

  5. Kreuter A et al. Association of autoimmune diseases with lichen sclerosus in 532 male and female patients. Acta Derm Venereol 2013;93(2):238–41

    Article  PubMed  Google Scholar 

  6. Kirtschig G et al. Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus. J Eur Acad Dermatol Venereol 2015; 29(10):e1–43

    Article  CAS  PubMed  Google Scholar 

  7. Powell J, Wojnarowska F. Childhood vulvar lichen sclerosus: an increasingly common problem. J Am Acad Dermatol 2001; 44(5):803–6

    Article  CAS  PubMed  Google Scholar 

  8. Sneppen I, Thorup J. Foreskin Morbidity in Uncircumcised Males. Pediatrics 2016; 137(5):pii:e20154340

    Article  PubMed  Google Scholar 

  9. Somov P et al. Bleeding after circumcision is more likely in childrenwith lichen sclerosus (balanitis xerotica obliterans). J Pediatr Urol 2017;13(2):208.e1–4

    CAS  Google Scholar 

  10. Higgins CA, Cruickshank ME. A population-based case-control study of aetiological factors associated with vulval lichen sclerosus. J Obstet Gynaecol 2012;32(3):271–5

    Article  CAS  PubMed  Google Scholar 

  11. Fallick ML et al. Balanitis xerotica obliterans in monozygotic twins. Br J Urol 1997; 79(5):810

    Article  CAS  PubMed  Google Scholar 

  12. Sentürk N et al. Coexistence of HLA-B*08 and HLA-B*18 in four siblings with Lichen sclerosus. Dermatology 2004;208(1):64–6

    Article  CAS  PubMed  Google Scholar 

  13. Powell J et al. Lichen sclerosus premenarche: autoimmunity and immunogenetics. Br J Dermatol 2000;142(3):481–4

    Article  CAS  PubMed  Google Scholar 

  14. Oyama N et al. Autoantibodies to extracellular matrix protein 1 in lichen sclerosus. Lancet 2003;362(9378):118–23

    Article  CAS  PubMed  Google Scholar 

  15. Lagerstedt M et al. Reduction in ERRα is associated with lichen sclerosus and vulvar squamous cell carcinoma. Gynecol Oncol 2015;139(3):536–40

    Article  CAS  PubMed  Google Scholar 

  16. Tegner E, Vrana I. Lichen sclerosus et atrophicus appearing in old scars of burns form welding sparks. Acta Derm Venereol 2001;81:211

    Article  CAS  PubMed  Google Scholar 

  17. Villa M M et al. Skin phototype and local trauma in the onset of balanitis xerotica obliterans (BXO) in circumcised patients. In Vivo 2012;26:143–6

    PubMed  Google Scholar 

  18. Jensen LS, Bygum A. Childhood lichen sclerosus is a rare but important diagnosis. Dan Med J 2012;59(5):A4424

    PubMed  Google Scholar 

  19. Frank JD et al. Urethral strictures in childhood. Br J Urol 1988;62(6):590–2

    Article  CAS  PubMed  Google Scholar 

  20. Borghi A et al. Clearance in vulvar lichen sclerosus: a realistic treatment endpoint or a chimera? J Eur Acad Dermatol Venereol 2018;32(1):96–101

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum der Rheinischen Friedrich-Wilhelms-Universität Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Deutschland

    Galina Balakirski

  2. http://www.springermedizin.de

    Julia Grothaus & Julia Altengarten

  3. Fachbereich Pädiatrische Dermatologie und Allergologie, Epidermolysis-bullosa-Zentrum Hannover, Kinder- und Jugendkrankenhaus AUF DER BULT, Hannover, Deutschland

    Hagen Ott

Authors
  1. Galina Balakirski
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Julia Grothaus
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Julia Altengarten
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hagen Ott
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Interessenkonflikt

Die Autoren erklären, dass bei der Erstellung des Beitrags kein Interessenkonflikt vorlag.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Balakirski, G., Grothaus, J., Altengarten, J. et al. Eine therapeutische Herausforderung. Pädiatrie 30, 34–37 (2018). https://doi.org/10.1007/s15014-018-1391-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s15014-018-1391-9

Search

Navigation