Skip to main content
Log in

Abklärung eines primären Immundefektes

Vorgehen beim infektionsanfälligen Kind

  • Fortbildung
  • Published:
Pädiatrie Aims and scope

Leidet ein Kind häufig unter Infektionen, kann dies auf einen primären Immundefekt hinweisen. Welche Basisdiagnostik hilft bei der Abklärung? Wann sollten Sie das Kind zu einem Spezialisten über weisen beziehungsweise ein Immundefektzentrum kontaktieren?

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1

Literatur

  1. Casanova JL, Abel L. The human model: a genetic dissection of immunity to infection in natural conditions. Nat Rev Immunol 2004;4:55–66

    Article  CAS  PubMed  Google Scholar 

  2. Monto AS, Sullivan KM. Acute respiratory illness in the community. Epidemiol Infect 1993;110:145–60

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Bustamante J et al. Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases. Curr Opin Immunol 2008;20:39–48

    Article  CAS  PubMed  Google Scholar 

  4. Patiroglu T et al. Atypical presentation of chronic granulomatous disease in an adolescent boy with frontal lobe located Aspergillus abscess mimicking intracranial tumor. Childs Nerv Syst 2010;26:149–54

    Article  PubMed  Google Scholar 

  5. Casanova JL et al. Immunological conditions of children with BCG disseminated infection. Lancet 1995;346: 581

    Article  CAS  PubMed  Google Scholar 

  6. Arason GJ et al. Primary immunodeficiency and autoimmunity: lessons from human diseases. Scand J Immunol 2010;71:317–28

    Article  CAS  PubMed  Google Scholar 

  7. Berron-Ruiz A et al. Cutaneous markers of primary immunodeficiency diseases in children. Pediatr Dermatol 2000;17:91–6

    Article  CAS  PubMed  Google Scholar 

  8. Guerrerio AL et al. Recognizing gastrointestinal and hepatic manifestations of primary immunodeficiency diseases. J Pediatr Gastroenterol Nutr 2010;51:548–55

    Article  PubMed  Google Scholar 

  9. Shapiro RS. Malignancies in the setting of primary immunodeficiency: Implications for hematologists/oncologists. Am J Hematol 2011;86:48–55

    Article  PubMed  Google Scholar 

  10. Notarangelo LD et al. Primary immunodeficiencies: 2009 update. J Allergy Clin Immunol 2009;124:1161–78

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Hayward AR et al. Delayed separation of the umbilical cord, widespread infections, and defective neutrophil mobility. Lancet 1979; 1:1099–110

    Article  CAS  PubMed  Google Scholar 

  12. Picard C et al. Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore) 2010;89:403–25

    Article  CAS  Google Scholar 

  13. de Vries E. Patient-centred screening for primary immunodeficiency, a multi-stage diagnostic protocol designed for non-immunologists: 2011 update. Clin Exp Immunol 2012;167:108–19

    Article  PubMed  PubMed Central  Google Scholar 

  14. Hauck F et al. Rational laboratory diagnostics of primary immunodeficiency disorders. Laboratoriumsmedizin-Journal of Laboratory Medicine 2015;39:343–54

    Google Scholar 

  15. Picard C et al. Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015. J Clin Immunol 2015;35:696–726

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Farmand S et al. Interdisciplinary AWMF guideline for the diagnostics of primary immunodeficiency. Klin Padiatr 2011;223:378–85

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Interessenkonflikt

Die Autoren erklären, dass bei der Erstellung des Beitrags kein Interessenkonflikt vorlag.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rack-Hoch, A., Notheis, G., Klein, C. et al. Vorgehen beim infektionsanfälligen Kind. Pädiatrie 29, 40–42 (2017). https://doi.org/10.1007/s15014-017-1018-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s15014-017-1018-6

Navigation