Die photodynamische Therapie ist eine vergleichsweise schonende und unkomplizierte Therapieoption zur effektiven Behandlung von aktinischen Keratosen, oberflächlichen Basalzellkarzinomen oder Morbus Bowen und eine beliebte Alternative zu operativen Eingriffen. Dennoch kann auch diese Therapieoption zu Nebenwirkungen führen, über die der Patient im Vorfeld dringend aufgeklärt werden muss.
Literatur
Braathen LR, Szeimies Rm, Basset-Seguin N, Bissonette R, Foley P, Pariser D, Roelandts R, Wennberg AM, Morton CA (2007) Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. J Am Acad Dermatol 56: 125–143
Kellner C, Bauriedl S. Hollstein S, Reinhold U (2015) Simulated-daylight photodynamic therapy with BF-200 aminolaevulic acid for actinic keratoses: assessment of the efficacy and tolerability in a retrospectiv study. Br J Dermatol: 172: 1146–1148
Lehmann P (2007) Nebenwirkungen der topischen photodynamischen Therapie. Der Hautarzt 58: 597–603
Lehmann P (2018) Tageslicht-photodynamische Therapie — Zurück in die Zukunft? Der Hautarzt 69: 180–183
Lerche CM, Heerfordt IM, Heydenreich J, Wulf HC (2016) Alternatives to outdoor daylight illumination for photodynamic therapy — use of greenhouses and artificial light sources. Int J Mol Sci 17: 309
Morton CA, Wulf HC, Szeimies RM, Gilaberte Y, Basset-Seguin N, Sotiriou E, Piaserico S, Hunger RE, Baharlou S, Sideroff A, Braathen LA (2015) Practical approach to the use of daylight photodynamic therapy with tropical methyl aminolevulinate for actinic keratosis: a European consensus. J Eur Acad Dermatol Venereol 29: 1718–1723
Morton C, Szeimies RM, Sidoroff A, Wennberg AM, Basset-Seguin N, Calzavarara-Pinton P, Gilaberte Y, Hofbauer G, Hunger R, Karrer S, Lehmann P, Piaserico S, Ulrich C, Braathen L (2015) European dermatology forum guidelines on topical photodynamic therapy. Eur J Dermatol 25: 296–311
O’Gorman Sm, Clowry J, Manley M, McCavana J, Gray L, Kavanagh A, Lally A, Collins P (2016) Artificial white light vs daylight photodynamic therapy for actinic keratosis. A randomized clinical trial. JAMA Dermatol 152: 638–644
Philipp-Dormston WG, Karrer S, Petering H, Ulrich C, Dirschka T, Berking C, Lonsdorf AS, Gerber PA, Radkovic S, Hunger RE, Szeimies RM (2015) Daylight PDT with MAL — current data and practical recommendations of an expert panel. J Dtsch Dermatol Ges 13: 1240–1249
Reinholz M, Heppt MV, Hoffmann FS, Lummel N, Ruzicka T, Lehmann P, Berking C (2015) Transient memory impairment and transient global amnesia induced by photodynamic therapy. Br J Dermatol 173: 1258–1262
Shive ML, Coakley BJ, Biermann DF, Serowka Lane KL, Wiegell SR, Haedersdal M, Zachary CB (2019) Use of 5-Aminolevlinic Acid and Daylight Photodynamic Therapy for the Treatment of Actinic Keratoses. Dermatol Surg 45: 529–535
Wiegell SR, Haedersdal M, Philipsen PA, Eriksen P, Enk CD, Wulf HC (2008) Continous activation of PpIX daylight is as effective as and less painful than conventional photodynamic therapy for actinic keratosis: a randomized controlled, single-blinded study. Br J Dermatol 158: 740–746
Wiegell SR, Fabricius S, Heydenreich J, Enk CD, Rosso S, Bäumler W, Baldursson BT, Wulf HC (2012) Weather conditions and daylight-mediated photodynamic therapy: protoporphyrin IX-weighted daylight doses measured in six geographical locations. Br J Dermatol 168: 186–191
Wiegell SR, Wulf HC, Szeimies RM, Basset-Seguin N, Bissonnette R, Gerritsen MJP, Gilaberte Y, Calzavara-Pinton P, Morton CA, Sideroff A, Braathen LR (2012) Daylight photodynamic therapy for actinic keratosis: an international consensus. J Eur Acad Dermatol Venereol 26: 673–679
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lehmann, P. Nebenwirkungen der photodynamischen Therapie. hautnah dermatologie 35, 32–36 (2019). https://doi.org/10.1007/s15012-019-3133-2
Published:
Issue Date:
DOI: https://doi.org/10.1007/s15012-019-3133-2