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PD-1-Blocker in der Zweitlinie beim Melanom

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hautnah dermatologie Aims and scope

Kommt es beim fortgeschrittenen malignen Melanom trotz Ipilimumab und BRAF-Inhibitoren zum Progress — lohnt sich dann in der Zweit- oder Drittlinie eine PD-1-Checkpointinhibition mehr als eine Chemotherapie?

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Literatur

  • Weber JS et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial. Lancet Oncol 2015; 16: 375–84

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von Kieseritzky, K. PD-1-Blocker in der Zweitlinie beim Melanom. hautnah dermatologie 31, 23 (2015). https://doi.org/10.1007/s15012-015-1887-8

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  • DOI: https://doi.org/10.1007/s15012-015-1887-8

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