Notes
Protocol described in the Moorfields Emergency Guidelines for Corneal and External Diseases within the free to download Microguide App http://www.microguide.eu/.
References
Ung L, Bispo PJM, Shanbhag SS, Gilmore MS, Chodosh J. The persistent dilemma of microbial keratitis: global burden, diagnosis, and antimicrobial resistance. Surv Ophthalmol. 2019;64(3):255–71. https://doi.org/10.1016/j.survophthal.2018.12.003 (published online first).
Dart JK, Radford CF, Minassian D, Verma S, Stapleton F. Risk factors for microbial keratitis with contemporary contact lenses: a case-control study. Ophthalmology. 2008;115(10):1647–54. https://doi.org/10.1016/j.ophtha.2008.05.003 (published online first).
Randag AC, van Rooij J, van Goor AT, et al. The rising incidence of Acanthamoeba keratitis: a 7-year nationwide survey and clinical assessment of risk factors and functional outcomes. PLoS ONE. 2019;14(9):e0222092. https://doi.org/10.1371/journal.pone.0222092 (published online first).
Carnt N, Robaei D, Minassian DC, Dart JKG. Acanthamoeba keratitis in 194 patients: risk factors for bad outcomes and severe inflammatory complications. Br J Ophthalmol. 2018;102(10):1431–5. https://doi.org/10.1136/bjophthalmol-2017-310806 (published online first).
Poon SHL, Wong WHL, Lo ACY, et al. A systematic review on advances in diagnostics for herpes simplex keratitis. Surv Ophthalmol. 2020. https://doi.org/10.1016/j.survophthal.2020.09.008 (published online first).
Labetoulle M, Auquier P, Conrad H, et al. Incidence of herpes simplex virus keratitis in France. Ophthalmology. 2005;112(5):888–95. https://doi.org/10.1016/j.ophtha.2004.11.052 (published online first).
Young RC, Hodge DO, Liesegang TJ, Baratz KH. Incidence, recurrence, and outcomes of herpes simplex virus eye disease in Olmsted County, Minnesota, 1976–2007: the effect of oral antiviral prophylaxis. Arch Ophthalmol. 2010;128(9):1178–83. https://doi.org/10.1001/archophthalmol.2010.187 (published online first).
Radford CF, Minassian DC, Dart JK. Acanthamoeba keratitis in England and Wales: incidence, outcome, and risk factors. Br J Ophthalmol. 2002;86(5):536–42. https://doi.org/10.1136/bjo.86.5.536 (published online first).
Funding
Part of John Dart’s salary was paid by the National Institute of Research (NIHR) Biomedical Research Centre (BRC) at Moorfields Eye Hospital and the UCL Institute of Ophthalmology.
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ALM designed and carried out the herpes simplex virus keratitis audit; JKGD and SS designed the Acanthamoeba keratitis audit; SS, DVW and LAF carried out the Acanthamoeba keratitis audit; JKGD designed the study; all authors contributed to manuscript preparation.
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Synopsis: Acanthamoeba keratitis (AK) is more common than herpes simplex virus keratitis (HSVK) in contact lens (CL) users in South-East England in first presentations of disease. In CL users, AK should be excluded before HSVK is diagnosed.
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Sanchez, S., Faraj, L.A., Wajnsztajn, D. et al. Acanthamoeba more commonly causes epithelial keratitis than herpes simplex in South-East England contact lens users. Infection 50, 1619–1622 (2022). https://doi.org/10.1007/s15010-022-01857-0
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DOI: https://doi.org/10.1007/s15010-022-01857-0