, Volume 46, Issue 3, pp 405–408 | Cite as

2016 PREP attitudes in Germany: high awareness and acceptance in MSM at risk of HIV

  • Christoph D. SpinnerEmail author
  • Nikola Hanhoff
  • Ivanka Krznaric
  • Gaby Knecht
  • Tim Kuemmerle
  • Robin Ruesenberg
  • Knud Schewe
Brief Report



To examine current risk behavior, awareness, experience, and attitudes towards pre-exposure-prophylaxis (PrEP), and to estimate a potential impact on the prevention of HIV transmission among HIV-negative MSM in Germany. PrEP was not officially licensed at the time of survey.


Web-based questionnaire from 03–06/2016. Potential participants were informed through social media, flyers, and advertisements. Risk contacts were defined as unprotected sexual intercourse under the influence of recreational drugs in the past 6 months.


In total, 1208 subjects participated, 342 subjects were excluded for being HIV-infected or non-MSM, leaving 866 subjects to be evaluated in this analysis. Mean age was 37.0 ± 10.4 years. 593 participants (68.5%) were tested for HIV within the past 12 months. A total of 206 STDs in the past 6 months were reported by 144 (16.6%). Aware of PrEP was 748 (86.4%) respondents, while 65.1% reported willingness to use it. Risk behavior was significantly associated with higher PrEP acceptance (OR 2.90, 95% CI 2.14–3.90), as was a history of STDs (OR 1.85, 95% CI 1.17–2.91). The use of condoms would forgo 52.3% of subjects if taking PrEP. Sixty-five respondents (7.5%) reported PrEP use. Only 19 (29.2%) had accessed PrEP under medical supervision. PrEP use was reported by 14.8% with > 5 risk contacts in the past 6 months, compared to 6.3% with one risk contact (p < 0.001).


We found a high PrEP awareness and acceptance, especially among subgroups of MSM at highest risk of HIV infection. Structured access and availability of PrEP to this population may have an important impact on the HIV epidemic in Germany.


HIV PrEP Prevention MSM 



No additional funding has been provided for this study.

Compliance with ethical standards

Conflict of interest

All authors declare that there is no relevant conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Christoph D. Spinner
    • 1
    Email author
  • Nikola Hanhoff
    • 2
  • Ivanka Krznaric
    • 3
  • Gaby Knecht
    • 4
  • Tim Kuemmerle
    • 5
  • Robin Ruesenberg
    • 2
  • Knud Schewe
    • 2
    • 6
  1. 1.Department of Medicine IIUniversity Hospital Klinikum Rechts der Isar, Technische Universität MünchenMunichGermany
  2. 2.German Association of Physicians Specialized in HIV Care (Dagnä e.V.)BerlinGermany
  3. 3.Zentrum für Infektiologie Prenzlauer BergBerlinGermany
  4. 4.InfektiologikumFrankfurtGermany
  5. 5.Praxis am EbertplatzCologneGermany
  6. 6.Infektionsmedizinisches Centrum Hamburg, Private PracticeHamburgGermany

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