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Francisella tularensis aortitis

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Abstract

Francisella tularensis, the agent of tularemia, is a Gram-negative coccobacillus primarily pathogen for animals and occasionally for humans. The clinical manifestations of tularemia include pneumonia, ulceroglandular, oropharyngeal, or typhoidal disease. Rare manifestations are also described, but to our knowledge, we describe here the first case of F. tularensis aortitis in a human. Diagnosis was confirmed by the presence of F. tularensis in blood culture, by the presence of F. tularensis DNA in the aortic biopsy and by specific IgG and IgM responses against the bacteria. The outcome was favorable after surgery and specific antimicrobial therapy.

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Authors and Affiliations

  1. Department of Infectious Diseases, CHU Nantes, Nantes, France

    M. Briere, C. Biron & D. Boutoille

  2. Department of Vascular Surgery, CHU Nantes, Nantes, France

    A. Kaladji

  3. Department of Radiology, CHU Nantes, Nantes, France

    F. Douane

  4. Department of Medicine and Infectious Diseases, CH Cholet, Cholet, France

    J. P. Breux

  5. Department of Microbiology, CH Cholet, Cholet, France

    P. Touroult-Jupin

  6. National Reference Center for Francisella, CHU Grenoble, Grenoble, France

    S. Boisset

  7. National Reference Center for Rickettsiosis and Francisella tularensis, Institut Hospital-Universitaire Méditerranée-Infection, Aix-Marseille Université, Marseille, France

    S. Edouard

Authors
  1. M. Briere
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  2. A. Kaladji
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  3. F. Douane
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  4. J. P. Breux
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  5. P. Touroult-Jupin
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  6. S. Boisset
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  7. S. Edouard
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  8. C. Biron
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  9. D. Boutoille
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Corresponding author

Correspondence to M. Briere.

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Briere, M., Kaladji, A., Douane, F. et al. Francisella tularensis aortitis. Infection 44, 263–265 (2016). https://doi.org/10.1007/s15010-015-0824-4

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  • DOI: https://doi.org/10.1007/s15010-015-0824-4

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