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Adrenal hypofunction from histoplasmosis: a literature review from 1971 to 2012

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An Erratum to this article was published on 01 April 2015

Abstract

Purpose

While histoplasmosis has been reported from most continents, the disease is most often recognized in the midwestern United States. The recent diagnosis of adrenal hypofunction in two patients with progressive disseminated histoplasmosis (PDH) in our hospital led us to review the literature.

Methods

We reviewed PubMed using the search term “adrenal histoplasmosis” for the years 1971 to 2012.

Results

The results included 242 patients with adrenal histoplasmosis from either case reports or case series. Most of the reported patients were from countries not previously considered to be heavily endemic for histoplasmosis. In addition, 41.3 % of patients with adrenal involvement developed adrenal hypofunction.

Conclusion

As modern technology elucidates more cases of adrenal histoplasmosis, the global boundaries of endemicity are being redefined.

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Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Authors and Affiliations

  1. Department of Medicine, University of Minnesota Medical Center, 420 Delaware St SE, Minneapolis, 55455, Minnesota, USA

    R. J. Koene & J. Catanese

  2. Veterans Affairs Medical Center, Minneapolis, Minnesota, USA

    G. A. Sarosi

Authors
  1. R. J. Koene
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  2. J. Catanese
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  3. G. A. Sarosi
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Corresponding author

Correspondence to R. J. Koene.

Additional information

An erratum to this article is available at http://dx.doi.org/10.1007/s15010-015-0767-9.

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Koene, R.J., Catanese, J. & Sarosi, G.A. Adrenal hypofunction from histoplasmosis: a literature review from 1971 to 2012. Infection 41, 757–759 (2013). https://doi.org/10.1007/s15010-013-0486-z

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