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Tularemia during pregnancy

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Abstract

Tularemia is a zoonotic infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. Although F. tularensis has been recognized as a human pathogen for a century, there are few reports regarding the occurrence of tularemia in pregnant women and its effect on the fetus; only seven cases have been reported in the literature. In view of the sparse literature, it is not clear whether tularemia increases the risk of adverse pregnancy outcomes. In this paper we review tularemia infection during pregnancy, its complications and management. In addition, we present a case of tularemia that occurred in the first trimester of pregnancy and resulted in third-trimester intrauterine fetal death, highlighting the consequences of tularemia in pregnancy and the importance of early detection and treatment.

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References

  1. World Health Organization (WHO). WHO guidelines on tularaemia. In: WHO guidelines. Geneva: WHO Press; 2007.

  2. Yeşilyurt M, Kiliç S, Celebi B, Gül S. Tularemia during pregnancy: report of four cases. Scand J Infect Dis. 2013;45:324–8.

    Google Scholar 

  3. Bricker D. Tularemia ınfection during pregnancy. Am J Nurs. 1931;31:979–82.

    Google Scholar 

  4. Dudley PB, Don CW. Tularemia and pregnancy: report of a case. J Am Med Assoc. 1936;107:577–8.

    Article  Google Scholar 

  5. Charles P, Stumpf P, Buffet P, Hot A, Lecuit M, Dupont B, Lortholary O, Consigny PH. Two unusual glandular presentations of tick-borne tularemia. Med Mal Infect. 2008;38:159–61.

    Article  PubMed  CAS  Google Scholar 

  6. Kavanaugh CN. Tularemia: a consideration of one hundred and twenty-three cases, with observations at autopsy in one free. Arch Intern Med. 1935;55:61–85.

    Article  Google Scholar 

  7. O’Toole D, Williams ES, Woods LW, et al. Tularemia in range sheep: an overlooked syndrome? J Vet Diagn Invest. 2008;20:508–13.

    Article  PubMed  Google Scholar 

  8. Health Protection Agency (UK). Tularemia guidelines for action in the event of a deliberate release. In: London; HPA Centre for Infections; 2009. Version 2.4.1 31. Available at: http://www.hpa.org.uk/web/HPAwebFile/HPAwebC/1194947357555. Accessed 12 Apr 2012.

  9. Yost NP, Cox SM. Infection and preterm labor. Clin Obstet Gynecol. 2000;43:759–67.

    Article  PubMed  CAS  Google Scholar 

  10. Romero R, Manogue KR, Mitchell MD, et al. Infection and labor. IV. Cachectin-tumor necrosis factor in the amniotic fluid of women with intraamniotic infection and preterm labor. Am J Obstet Gynecol. 1989;161:336–41.

    Article  PubMed  CAS  Google Scholar 

  11. Kılıç S. A General Overview of Francisella tularensis and the epidemiology of tularemia in Turkey. Flora. 2010;15:37–58.

    Google Scholar 

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Authors and Affiliations

  1. Department of Otorhinolaryngology, Konya Training and Research Hospital, Hacı Şaban Mah. Meram Yeniyol Caddesi No:97, 42040, Meram, Konya, Turkey

    N. Ata, G. Övet & N. Alataş

  2. National Tularemia Reference Laboratory, Public Health Institution of Turkey, Adnan Saygun Cad. 55, 06100, Sıhhıye, Ankara, Turkey

    S. Kılıç & B. Çelebi

Authors
  1. N. Ata
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  2. S. Kılıç
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  3. G. Övet
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  4. N. Alataş
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  5. B. Çelebi
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Correspondence to S. Kılıç.

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Ata, N., Kılıç, S., Övet, G. et al. Tularemia during pregnancy. Infection 41, 753–756 (2013). https://doi.org/10.1007/s15010-013-0456-5

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  • DOI: https://doi.org/10.1007/s15010-013-0456-5

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