, Volume 40, Issue 4, pp 463–468 | Cite as

Mycobacterium szulgai: an unusual cause of disseminated mycobacterial infections

  • S. Riedel
  • K. Dionne
  • C. Ellis
  • A. Duffield
  • K. C. Carroll
  • N. M. Parrish


  1. 1.
    Falkinham JO. Epidemiology of infection by nontuberculous mycobacteria. Clin Microbiol Rev. 1996;9:177–215.PubMedGoogle Scholar
  2. 2.
    Horsburgh CR Jr, Selik RM. The epidemiology of disseminated nontuberculous mycobacterial infection in the acquired immunodeficiency syndrome (AIDS). Am Rev Respir Dis. 1989;139:4–7.PubMedCrossRefGoogle Scholar
  3. 3.
    Horsburgh CR Jr. Epidemiology of mycobacterial diseases in AIDS. Res Microbiol. 1992;143:372–7.PubMedCrossRefGoogle Scholar
  4. 4.
    Saleeb P, Olivier KN. Pulmonary nontuberculous mycobacterial disease: new insights into risk factors for susceptibility, epidemiology, and approaches to management in immunocompetent and immunocompromised patients. Curr Infect Dis Rep. 2010;12:198–203.PubMedCrossRefGoogle Scholar
  5. 5.
    Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, Holland SM, Horsburgh R, Huitt G, Iademarco MF, Iseman M, Olivier K, Ruoss S, von Reyn CF, Wallace RJ Jr, Winthrop K; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175:367–416.PubMedCrossRefGoogle Scholar
  6. 6.
    van Ingen J, Boeree MJ, de Lange WC, de Haas PE, Dekhuijzen PN, van Soolingen D. Clinical relevance of Mycobacterium szulgai in The Netherlands. Clin Infect Dis. 2008;46:1200–5.PubMedCrossRefGoogle Scholar
  7. 7.
    van Ingen J, Verhagen AF, Dekhuijzen PN, van Soolingen D, Magis-Escurra C, Boeree MJ, de Lange WC. Surgical treatment of non-tuberculous mycobacterial lung disease: strike in time. Int J Tuberc Lung Dis. 2010;14:99–105.PubMedGoogle Scholar
  8. 8.
    Marks J, Jenkins PA, Tsukamura M. Mycobacterium szulgai—a new pathogen. Tubercle. 1972;53:210–4.PubMedCrossRefGoogle Scholar
  9. 9.
    Tortoli E, Besozzi G, Lacchini C, Penati V, Simonetti MT, Emler S. Pulmonary infection due to Mycobacterium szulgai, case report and review of the literature. Eur Respir J. 1998;11:975–7.PubMedCrossRefGoogle Scholar
  10. 10.
    Clinical and Laboratory Standards Institute (CLSI) (2008) Laboratory detection and identification of mycobacteria; approved guideline. CLSI document M48-A. CLSI, Wayne, PA, USA.Google Scholar
  11. 11.
    Schaefer WB, Wolinsky E, Jenkins PA, Marks J. Mycobacterium szulgai—a new pathogen. Serologic identification and report of five new cases. Am Rev Respir Dis. 1973;108:1320–6.PubMedGoogle Scholar
  12. 12.
    Cross GM, Guill MA, Aton JK. Cutaneous Mycobacterium szulgai infection. Arch Dermatol. 1985;121:247–9.PubMedCrossRefGoogle Scholar
  13. 13.
    Tappe D, Langmann P, Zilly M, Klinker H, Schmausser B, Frosch M. Osteomyelitis and skin ulcers caused by Mycobacterium szulgai in an AIDS patient. Scand J Infect Dis. 2004;36:883–5.PubMedCrossRefGoogle Scholar
  14. 14.
    Gur H, Porat S, Haas H, Naparstek Y, Eliakim M. Disseminated mycobacterial disease caused by Mycobacterium szulgai. Arch Intern Med. 1984;144:1861–3.PubMedCrossRefGoogle Scholar
  15. 15.
    Luque AE, Kaminski D, Reichman R, Hardy D. Mycobacterium szulgai osteomyelitis in an AIDS patient. Scand J Infect Dis. 1998;30:88–91.PubMedCrossRefGoogle Scholar
  16. 16.
    Roy V, Weisdorf D. Mycobacterial infections following bone marrow transplantation: a 20 year retrospective review. Bone Marrow Transplant. 1997;19:467–70.PubMedCrossRefGoogle Scholar
  17. 17.
    Janka GE. Hemophagocytic syndromes. Blood Rev. 2007;21:245–53.PubMedCrossRefGoogle Scholar
  18. 18.
    Martin-Moreno S, Soto-Guzmán O, Bernaldo-de-Quirós J, Reverte-Cejudo D, Bascones-Casas C. Pancytopenia due to hemophagocytosis in patients with brucellosis: a report of four cases. J Infect Dis. 1983;147:445–9.PubMedCrossRefGoogle Scholar
  19. 19.
    Doutre MS, Beylot C, Maugein J, Boisseau AM, Long P, Royer P, Roy C. Cutaneous infection caused by Mycobacterium malmoense in a patient with myelodysplastic syndrome. J R Soc Med. 1993;86:110–1.PubMedGoogle Scholar
  20. 20.
    Meyer JJ, Gelman SS. Multifocal osteomyelitis due to Mycobacterium szulgai in a patient with chronic lymphocytic leukemia. J Infect. 2008;56:151–4.PubMedCrossRefGoogle Scholar
  21. 21.
    Nakada S, Sekikawa T, Takahara S, Yamazaki Y, Yamada J, Yamada H, Iwase S, Kobayashi M. Nontuberculous atypical mycobacterial infection with progressive pancytopenia in a patient with myelodysplastic syndrome. Rinsho Ketsueki. 2001;42:543–8 (article in Japanese).PubMedGoogle Scholar
  22. 22.
    Benator DA, Kan V, Gordin FM. Mycobacterium szulgai infection of the lung: case report and review of an unusual pathogen. Am J Med Sci. 1997;313:346–51.PubMedCrossRefGoogle Scholar
  23. 23.
    Pozniak A, Bull T. Recently recognized mycobacteria of clinical significance. J Infect. 1999;38:157–61.PubMedCrossRefGoogle Scholar
  24. 24.
    Piersimoni C, Scarparo C. Pulmonary infections associated with non-tuberculous mycobacteria in immunocompetent patients. Lancet Infect Dis. 2008;8:323–34.PubMedCrossRefGoogle Scholar
  25. 25.
    Hurr H, Sorg T. Mycobacterium szulgai osteomyelitis. J Infect. 1998;37:191–2.PubMedCrossRefGoogle Scholar
  26. 26.
    Maloney JM, Gregg CR, Stephens DS, Manian FA, Rimland D. Infections caused by Mycobacterium szulgai in humans. Rev Infect Dis. 1987;9:1120–6.PubMedCrossRefGoogle Scholar
  27. 27.
    Casanova JL, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol. 2002;20:581–620.PubMedCrossRefGoogle Scholar
  28. 28.
    Newshan G, Torres RA. Pulmonary infection due to multidrug-resistant Mycobacterium szulgai in a patient with AIDS. Clin Infect Dis. 1994;18:1022–3.PubMedCrossRefGoogle Scholar
  29. 29.
    Sánchez-Alarcos JM, de Miguel-Díez J, Bonilla I, Sicilia JJ, Alvarez-Sala JL. Pulmonary infection due to Mycobacterium szulgai. Respiration. 2003;70:533–6.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • S. Riedel
    • 1
  • K. Dionne
    • 2
  • C. Ellis
    • 3
  • A. Duffield
    • 3
  • K. C. Carroll
    • 2
  • N. M. Parrish
    • 2
  1. 1.Department of Pathology, Division of MicrobiologyThe Johns Hopkins University, School of Medicine, Johns Hopkins Bayview Medical CenterBaltimoreUSA
  2. 2.Department of Pathology, Division of MicrobiologyThe Johns Hopkins University, School of Medicine, The Johns Hopkins HospitalBaltimoreUSA
  3. 3.Department of PathologyThe Johns Hopkins University, School of Medicine, The Johns Hopkins HospitalBaltimoreUSA

Personalised recommendations