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Osteomyelitis due to trimethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease

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Abstract

Edwardsiella tarda, a catalase-positive bacillus widely distributed throughout nature, is generally susceptible to trimethoprim/sulfamethoxazole. We describe osteomyelitis due to trimethoprim/sulfamethoxazole-resistant E. tarda in a patient with chronic granulomatous disease (CGD). Once E. tarda acquires antibiotic resistance, infected CGD patients may develop severe infections with unforeseeable consequences.

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References

  1. Janda JM, Abbott SL. Infections associated with the genus Edwardsiella: the role of Edwardsiella tarda in human disease. Clin Infect Dis. 1993;17(4):742–8.

    Article  PubMed  CAS  Google Scholar 

  2. Jordan GW, Hadley WK. Human infection with Edwardsiella tarda. Ann Intern Med. 1969;70(2):283–8.

    PubMed  CAS  Google Scholar 

  3. Sonnenwirth AC, Kallus BA. Meningitis due to Edwardsiella tarda. First report of meningitis caused by E. tarda. Am J Clin Pathol. 1968;49(1):92–5.

    PubMed  CAS  Google Scholar 

  4. Golub V, Kim AC, Krol V. Surgical wound infection, tuboovarian abscess, and sepsis caused by Edwardsiella tarda: case reports and literature review. Infection. 2010;38(6):487–9. doi:10.1007/s15010-010-0057-5.

    Article  PubMed  CAS  Google Scholar 

  5. Kobayashi S, Murayama S, Takanashi S, Takahashi K, Miyatsuka S, Fujita T, et al. Clinical features and prognoses of 23 patients with chronic granulomatous disease followed for 21 years by a single hospital in Japan. Eur J Pediatr. 2008;167(12):1389–94.

    Article  PubMed  Google Scholar 

  6. Shigemura T, Agematsu K, Yamazaki T, Eriko K, Yasuda G, Nishimura K, et al. Femoral osteomyelitis due to Cladophialophora arxii in a patient with chronic granulomatous disease. Infection. 2009;37(5):469–73.

    Article  PubMed  CAS  Google Scholar 

  7. Martire B, Rondelli R, Soresina A, Pignata C, Broccoletti T, Finocchi A, et al. Clinical features, long-term follow-up and outcome of a large cohort of patients with chronic granulomatous disease: an Italian multicenter study. Clin Immunol. 2008;126(2):155–64.

    Article  PubMed  CAS  Google Scholar 

  8. Holland SM. Chronic granulomatous disease. Clin Rev Allergy Immunol. 2010;38(1):3–10.

    Article  PubMed  CAS  Google Scholar 

  9. Huovinen P. Resistance to trimethoprim–sulfamethoxazole. Clin Infect Dis. 2001;32(11):1608–14.

    Article  PubMed  CAS  Google Scholar 

  10. Moreno E, Prats G, Sabaté M, Pérez T, Johnson JR, Andreu A. Quinolone, fluoroquinolone and trimethoprim/sulfamethoxazole resistance in relation to virulence determinants and phylogenetic background among uropathogenic Escherichia coli. J Antimicrob Chemother. 2006;57(2):204–11.

    Article  PubMed  CAS  Google Scholar 

  11. Morpeth SC, Ramadhani HO, Crump JA. Invasive non-typhi Salmonella disease in Africa. Clin Infect Dis. 2009;49(4):606–11.

    Article  PubMed  Google Scholar 

  12. Guglierame P, Pasca MR, De Rossi E, Buroni S, Arrigo P, Manina G, et al. Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome. BMC Microbiol. 2006;6:66.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Human Genetics, National Center for Child Health and Development, Tokyo, Japan

    T. Kawai, S. Kobayashi & M. Onodera

  2. Division of Immunology, National Center for Child Health and Development, Tokyo, Japan

    T. Kawai & M. Onodera

  3. Division of Orthopedics, National Center for Child Health and Development, Tokyo, Japan

    H. Kusakabe & A. Seki

  4. Department of Genetics, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan

    T. Kawai

Authors
  1. T. Kawai
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  2. H. Kusakabe
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  3. A. Seki
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  4. S. Kobayashi
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  5. M. Onodera
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Corresponding author

Correspondence to T. Kawai.

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Kawai, T., Kusakabe, H., Seki, A. et al. Osteomyelitis due to trimethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease. Infection 39, 171–173 (2011). https://doi.org/10.1007/s15010-011-0080-1

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  • DOI: https://doi.org/10.1007/s15010-011-0080-1

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