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Herpes Simplex Encephalitis – An Atypical Case


Herpes simplex virus (HSV) is a common cause of viral encephalitis. Herpes simplex encephalitis (HSE) typically presents with acute neurologic changes and the initial cerebrospinal fluid examination is nearly always abnormal. We report a case of a patient with HSE and normal initial CSF analysis. This resulted in delayed diagnosis and therapy with subsequent severe neurolgical sequelae. Herpes simplex infection should be included in the differential diagnosis of encephalopathic patients and a normal CSF examination.

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Received: August 16, 2000 · Revision accepted: August 27, 2001

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Razavi, B., Razavi, M. Herpes Simplex Encephalitis – An Atypical Case. Infection 29, 357–358 (2001).

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  • Key Words Herpes simplex virus
  • Viral encephalitis