Zusammenfassung
Luftgetragene allergene Pollen sind ein relevanter Bestandteil von Bioaerosolen und damit von luftgetragenen Partikeln. Sie gelten als wichtige Messgröße bei der Beurteilung der Luftqualität. Obwohl die Messung der Konzentration von allergenen Pollen in der Außenluft (insbesondere in städtischen Gebieten) als wichtiger Indikator für die Umweltgesundheit anerkannt ist, besteht für Innenräume (Wohnungen oder Arbeitsumgebungen) keine solche Verpflichtung. Allerdings verbringen Menschen den Großteil ihrer Zeit (80−90 %) in Innenräumen, wo sie dem größten Anteil der Luftschadstoffexposition, einschließlich der Pollenexposition, ausgesetzt sind.
Dennoch unterscheidet sich die relative Bedeutung der Exposition gegenüber allergenen Pollen in Innenraumluft von der Exposition in Außenluft aufgrund unterschiedlicher Pollenbelastungen, Pollenquellen, Pollenverbreitung sowie unterschiedlichem Pollendurchdringungsgrad von außen nach innen und aufgrund der Unterschiede in den allergenen Pollenprofilen. In diesem Kurz-Review wurde die wissenschaftliche Literatur der letzten zehn Jahre gesichtet, um zusammenzufassen, was die vorliegenden Messdaten über die Relevanz luftgetragener allergener Pollen in Innenräumen aussagen.
Die Forschungsprioritäten zu diesem Thema werden vorgestellt und die Herausforderungen sowie Beweggründe für die Erhebung von Pollendaten in der bebauten Umwelt hervorgehoben, die für das Verständnis des Ausmaßes und der Mechanismen der menschlichen Exposition gegenüber allergenen Pollen in der Luft von entscheidender Bedeutung sind. Somit bieten wir eine umfassende Beurteilung der Relevanz luftgetragener allergener Pollen in Innenräumen und heben Wissenslücken sowie die damit verbundenen Forschungsbedarfe im Zusammenhang mit den Gesundheitsauswirkungen hervor.
Zitierweise: Nehr S, Duarte RMBO, Almeida AS, Baus L, Bergmann K-C. Assessing the relevance of allergenic pollen in indoor environments - current knowledge base and research needs. Allergo J Int 2023;32:167-75
Literatur
Zuberbier T, Lötvall J, Simoens S, Subramanian SV, Church MK. Economic burden of inadequate management of allergic diseases in the European Union: a GA2LEN review. Allergy 2014;69:1275-9
World Health Organization. WHO global air quality guidelines. Particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. World Health Organization: Geneva, Switzerland, 2021
University of Turku, Aerobiology Unit. Norkko. www.norkko.fi/?lang=en&_ga=2.155130939.261610194.1502867863-1583081220.1493019326. Accessed on 29.4.2023
Réseau National De Surveillance Aérobiologique. www.pollens.fr/en/. Accessed on 29.4.2023
Met Office. Pollen forecasts. www.metoffice.gov.uk/weather/warnings-and-advice/seasonal-advice/pollen-forecast. Accessed on 29.4.2023
Medizinische Universität Wien, Forschungsgruppe Aerobiologie und Polleninformation. www.pollenwarndienst.at/?iframe=0ghjscjm%2522 Accessed on 29 April 2023
Federal Office of Meteorology and Climatology MeteoSwiss. Pollen monitoring network. www.meteoswiss.admin.ch/home/measurement-and-forecasting-systems/land-based-stations/pollen-monitoring-network.html. Accessed on 29 April 2023
Stiftung Deutscher Polleninformationsdienst. Pollenvorhersage. www.pollenstiftung.de/pollenvorhersage.html. Accessed on 29.4.2023
Fachübergreifender Arbeitskreis "Bundesweites Pollenmonitoring". Perspektiven für ein bundesweites Pollenmonitoring in Deutschland. Bundesgesundheitsblatt 2019;62:652-66
Code de l'environnement, Article L-221-1. Arrêté du 5 août 2016 portant désignation des organismes chargés de coordonner la surveillance des pollens et des moisissures de l'air ambient. Journal Officiel De La République Française 2016
Clot B, Gilge S, Hajkova L, Magyar D, Scheifinger H, Sofiev M et al. The EUMETNET AutoPollen programme: establishing a prototype automatic pollen monitoring network in Europe. Aerobiologia 2020. https://doi.org/10.1007/s10453-020-09666-4
International Organization for Standardization. ISO 16814: Building environment design - Indoor air quality - Methods of expressing the quality of indoor air for human occupancy. 2008
International Organization for Standardization. ISO 16890-1: Air filters for general ventilation - Part 1: Technical specifications, requirements and classification system based upon particulate matter efficiency (ePM). 2016
International Organization for Standardization. ISO 16890-2: Air filters for general ventilation - Part 2: Measurement of fractional efficiency and flow resistance. 2022
International Organization for Standardization. ISO 16890-3: Air filters for general ventilation - Part 3: Determination of the gravimetric efficiency and the air flow resistance versus the mass of test dust captured. 2016
International Organization for Standardization. ISO 16890-4: Air filters for general ventilation - Part 4: Conditioning method to determine the minimum fractional test efficiency. 2022
International Organization for Standardization. ISO/AWI 16890-5: Air filters for general ventilation - Part 5: Measurement of fractional efficiency and air flow resistance for flat sheet filter media. Under development
European Committee for Standardization. EN 1822-1. High efficiency air filters (EPA, HEPA and ULPA) - Part 1: Classification, performance testing, marking. 2019
Verein Deutscher Ingenieure. VDI 3803-4: Air-conditioning - System requirements - Air filter systems (VDI Ventilation Code of Practice). 2021
Verein Deutscher Ingenieure. VDI 6022-5: Ventilation and indoor-air quality − Avoidance of allergenic exposure − Requirements regarding the testing and evaluation of technical products and components affecting the indoor air. 2016
Bastl K, Berger U, Kmenta M. Ten questions about pollen and symptom load and the need for indoor measurements in built environment. Building and Environment 2016;98:200-8
Royal Society of Chemistry. Environmental Science: Atmospheres. Advanced Search. https://pubs.rsc.org/en/journals/journalissues/ea#!recentarticles&adv. Accessed on 29.4.2023
ScienceDirect. Advanced Search. www.sciencedirect.com/search. Accessed on 29.4.2023
Wiley Online Library. Advanced Search. https://onlinelibrary.wiley.com/search/advanced. Accessed on 29.4.2023
Clarivate. Web of Science. https://mjl.clarivate.com/home. Accessed on 29.4.2023
Tizek L, Redlinger E, Ring J, Eyerich K, Biedermann T, Zink A. Urban vs rural - Prevalence of self-reported allergies in various occupational and regional settings. World Allergy Organization Journal 2022;15:100625
Wang W, Ooka R, Kikumoto H, Oh W, Han M. Influence of various factors on indoor/outdoor pollen concentration ratio based on experimental research: A review. Building and Environment 2022;219:109154
Jochner-Oette S, Jetschni J, Liedl P, Menzel A. Indoor pollen concentration of Mountain Cedar (Juniperus ashei) during rainy episodes in Austin, Texas. International Journal of Environmental Research and Public Health 2022;19:1541
Núnez A, García AM. Effect of the passive natural ventilation on the bioaerosol in a small room. Building and Environment 2022;207:108438
Deng X, Thurston G, Zhang W, Ryan I, Jiang C, Khwaja H et al. Application of data science methods to identify school and home risk factors for asthma and allergy-related symptoms among children in New York. Sci Total Environ 2021;770:144746
Suzuki N, Nakayama Y, Nakaoka Y, Takaguchi K, Tsumura K, Hanazato M et al. Risk factors for the onset of sick building syndrome: A cross-sectional survey of housing and health in Japan. Building and Environment 2021;202:107976
Lu R, Pørneki AD, Lindgreen JN, Li Y, Madsen AM. Species of fungi and pollen in the PM1 and the inhalable fraction of indoor air in homes. Atmosphere 2021;12:404
D'Ovidio MC, Di Renzi S, Capone P, Pelliccioni A. Pollen and fungal spores evaluation in ration to occupants and microclimate in indoor workplaces. Sustainability 2021;6:3154
Pelliccioni A, Ciardini V, Lancia A, Di Renzi S, Brighetti MA, Travaglini A et al. Intercomparison of indoor and outdoor pollen concentrations in rural and suburban research workplaces. Sustainability 2021;13:8776
Dbouk T, Drikakis D. On pollen and airborne virus transmission. Physics of Fluids 2021;33:063313
Lowther SD, Deng W, Fang Z, Booker D, Whyatt DJ, Wild O et al. How efficiently can HEPA purifiers remove priority fine and ultrafine particles from indoor air? Environment International 2020;144:106001
Caraballo L, Valenta R, Puerta L, Pomés A, Zakzuk J, Fernandez-Caldas E et al. The allergenic activity and clinical impact of individual IgE-antibody binding molecules from indoor allergen sources. World Allergy Organization Journal 2020;13:100118
Li J, Wan MP, Schiavon S, Tham KW, Zuraimi S, Xiong J et al. Size-resolved dynamics of indoor and outdoor fluorescent biological aerosol particles in a bedroom: A one-month case study in Singapore. Indoor Air 2020;5:942-54
García-Mozo H, López-Orozco R, Canalejo C, Oteros J. Indoor biological particles in a train: comparative analysis with outdoor atmosphere. Aerobiologia 2020;36:481-92
Reponen T. Methodologies for assessing bioaerosol exposures. Encyclopedia of Environmental Health 2019; Second Edition: 342-50. https://doi.org/10.1016/B978-0-12-409548-9.11822-6
Damialis A, Häring F, Gökkaya M, Rauer D, Reiger M, Bezold Set al. Human exposure to airborne pollen and relationships with symptoms and immune responses: Indoors versus outdoors, circadian patterns and meteorological effects in alpine and urban environments. Sci Total Environ 2019;653:190-199
Gola M, Settimo G, Capolongo S. Indoor air quality in inpatient environments: A systematic review on factors that influence chemical pollution in inpatient wards. J Healthc Eng 2019;8358306
Li L, Zhang L, Mo JH, Li YY, Xia JY, Bai XB et al. Efficacy of indoor air purification in the treatment of Artemisia pollen-allergic rhinitis: A randomized, double-blind, clinical controlled trial. Clin Otolaryngol 2020;45:394-401
Kuzdak M, Jerzynska J, Stelmach I, Podlecka D, Majak P, Janas A et al. Associations between sensitization to perennial/seasonal allergens and childhood asthma. Allergol select 2018;2:151-5
Bastl K, Berger U, Kmenta M, Weber M. Is there an advantage to staying indoors for pollen allergy sufferers? Composition and quantitative aspects of the indoor pollen spectrum. Building and Environment 2017;123:78-87
Ercilla-Montserrat M, Izquierdo R, Belmonte J, Ignacio Montero J, Muñoz P, De Linares C et al. Building-integrated agriculture: A first assessment of aerobiological air quality in rooftop greenhouses (i-RTGs). Sci Total Environ 2017;598:109-20
Bergmann KC, Sehlinger T, Gildemeister J, Zuberbier T. A novel experimental technology for testing efficacy of air purifiers on pollen reduction. Allergo J Int 2017;26:1-6
Craine JM, Barberán A, Lynch RC, Menninger HL, Dunn RR, Fierer N. Molecular analysis of environmental plant DNA in house dust across the United States. Aerobiologia 2017;33:71-86
Korpelainen H, Pietiläinen M. Biodiversity of pollen in indoor air samples as revealed by DNA metabarcoding. Nord J Bot 2017;35:602-8
Menzel A, Matiu M, Michaelis R, Jochner S. Indoor birch pollen concentrations differ with ventilation scheme, room location, and meteorological factors. Indoor Air 2017;27:539-550. https://doi.org/10.1111/ina.12351
Nguyen P, Weber M. Can pollen match shoes to a previously visited indoor location? Grana 2016;55:164-172.
Pichot C, Calleja M, Penel V, Bues-Charbit M, Charpin D. Inference of the pollen penetration and remanence into dwellings using seasonal variation of indoor/outdoor pollen counts. Aerobiologia 2015;31;315-22
Preusche P, Weber M. Monitoring indoor pollen over two years. Grana 2014;53:133-46
Nayar TS, Jothish PS. An assessment of the air quality in indoor and outdoor air with reference to fungal spores and pollen grains in four working environments in Kerala, India. Aerobiologia 2013;29:131-52
Beggs PJ. Climate change, aeroallergens, and the aeroexposome. Environmental Research letters 2021;16:035006.
El Kelish A, Zhao F, Heller W, Durner J, Winkler JB, Behrendt H et al. (Ambrosia artemisiifolia) pollen allergenicity: SuperSAGE transcriptomic analysis upon elevated CO2 and drought stress. BMC Plant Biol 2014;14:176
Ziska LH, Makra L, Harry SK, Bruffaerts N, Hendrickx M, Coates F et al. Temperature-related changes in airborne allergenic pollen abundance and seasonality across the northern hemisphere: a retrospective data analysis. Lancet Planet Health 2019;3:E124-31
Polling M, Li C, Cao L, Verbeek F, de Weger A, Belmonte J et al. Neural networks for increased accuracy of allergenic pollen monitoring. Sci Rep 2021;11:11357
Reisman RE, Mauriello PM, Davis GB, Georgitis JW, DeMasi JM. A double-blind study of the effectiveness of a high-efficiency particulate air (HEPA) filter in the treatment of patients with perennial allergic rhinitis and asthma. J Allergy Clin Immunol 1990;85:1050-7
Sublett JL. Effectiveness of air filters and air cleaners in allergic respiratory diseases: A review of the recent literature. Curr Allergy Asthma Rep 2011;11:395-402
Park KH, Sim DW, Lee SC, Moon S, Choe E, Shin H et al. Effects of air purifiers on patients with allergic rhinitis: a multicenter, randomized, double-blind, and placebo-controlled study. Yonsei Med J 2020;61:689-97
Eduard W. Fungal spores: A critical review of the toxicological and epidemiological evidence as a basis for occupational exposure limit setting. Critical Reviews in Toxicology 2009;39:799-864
Danksagung
Dank gilt der European Cooperation in Science and Technology (COST) für die Bereitstellung einer Netzwerkplattform im Rahmen des COST Action INDoor AIR POLLution NETwork (INDAIRPOLLNET, CA17136). FCT/MCTES gilt Dank für die finanzielle Unterstützung des CESAM - Zentrums für Umwelt- und Meeresstudien (UIDP/50017/2020+UIDB/50017/2020+LA/P/0094/2020) durch nationale Mittel sowie für eine Promotionsförderung (Antoine S. Almeida − 2020.05804.BD) aus nationalen Mitteln und dem europäischen Sozialfonds.
Author information
Authors and Affiliations
Contributions
Konzeptualisierung, Methodik, Textverfassung: S. Nehr, R. M. B. O. Duarte, A. S. Almeida, L. Baus und K.-C. Bergmann. Alle Autoren haben die veröffentlichte Version des Manuskripts gelesen und ihr zugestimmt.
Ethics declarations
Die Autoren geben an, dass kein Interessenkonflikt besteht.
Rights and permissions
About this article
Cite this article
Nehr, S., Duarte, R., Almeida, A. et al. Bewertung der Relevanz allergener Pollen in Innenräumen - aktueller Wissensstand und Forschungsbedarf. Allergo J 32, 40–49 (2023). https://doi.org/10.1007/s15007-023-5790-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s15007-023-5790-z