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Eosinophil-basophil progenitors and atopic risk

Eosinophil-basophile Vorläufer und atopisches Risiko

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Fig. 1

Abbreviations

ALI:

Air liquid interface

CB:

Cord blood

CFU:

Colony-forming unit

Eo/B:

Eosinophil-basophil

GM-CSF:

Granulocyte-macrophage colony-stimulating factor

HBEC:

Human bronchial epithelial cells

HCR:

Hemopoietic cytokine receptors

IL:

Interleukin

PB:

Peripheral blood

Q-PCR:

Quantitative polymerase chain reaction

TLR:

Toll-like receptor

TSLP:

Thymic stromal lymphopoietin

References

  1. Hui CCK, Murphy DM, Thong B, Delespesse G, Denburg JA, Larché M. Induction of thymic stromal lymphopoietin (TSLP) in airway epithelium by recombinant allergens. J Allergy Clin Immunol 2011;127 suppl: AB125

  2. Hui CCK, Rusta-Sallehy S, Heroux D, Denburg JA. Thymic stromal lymphopoietin promotes peripheral blood CD34+ cell eosinophilic lineage commitment. J Allergy Clin Immunol 2013;131 suppl: AB239

  3. Allakhverdi Z, Comeau MR, Jessup HK, Yoon BR, Brewer A, Chartier S et al. Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells. J Exp Med 2007; 204: 253–8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Kato A, Favoreto S, Jr., Avila PC, Schleimer RP. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J Immunol 2007; 179: 1080–7

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Reece P, Thanendran A, Crawford L, Tulic MK, Thabane L, Prescott SL et al. Maternal allergy modulates cord blood hematopoietic progenitor Toll-like receptor expression and function. J Allergy Clin Immunol 2011; 127: 447–53

    Article  CAS  PubMed  Google Scholar 

  6. Omana VN, Ellis AK. Q-PCR analysis of GATA-1 in umbilical cord blood: optimizing RNA extraction and reverse transcription techniques. J Allergy Clin Immunol 2013; 131 suppl: AB212

  7. Thiele J, Ellis AK. Identification of suitable qPCR reference genes during IL-5 induced cord blood eosinophilopoiesis. J Allergy Clin Immunol 2012; 129 suppl: AB119

  8. Reece P, Baatjes AJ, Cyr MM, Sehmi R, Denburg JA. Toll-like receptor-mediated eosinophil-basophil differentiation: autocrine signalling by granulocyte-macrophage colony-stimulating factor in cord blood haematopoietic progenitors. Immunology 2013; 139: 256–64

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Acknowledgments

This research was supported in part by grants from the Canadian Institutes of Health Research (CIHR #84506 (ML) and #111029 (JAD)) and AllerGen NCE (JAD).

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Authors and Affiliations

  1. McMaster University, HSC-3V46, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada

    Judah Denburg

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  1. Judah Denburg
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Correspondence to Judah Denburg.

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The authors declare that no conflicts of interests exist.

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Denburg, J. Eosinophil-basophil progenitors and atopic risk. Allergo J 22, 553–555 (2013). https://doi.org/10.1007/s15007-013-0443-2

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  • DOI: https://doi.org/10.1007/s15007-013-0443-2

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