Skip to main content
Log in

Genügen ein Kreatininwert und ein Urinstix?

Nierenerkrankungen bei HIV-Patienten

Is a creatinine value and a urine stix sufficient?

  • FORTBILDUNG -- ÜBERSICHT
  • Published:
MMW - Fortschritte der Medizin Aims and scope

Bei Menschen mit einer HIV-Infektion besteht ein erhöhtes Risiko für Nierenerkrankungen. Durch sorgfältiges und regelmäßiges Monitoring können renale Probleme rechtzeitig erkannt werden. Bei einem Teil der Patienten muss dann auch die antiretrovirale Therapie angespasst werden.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Tab. 1
Tab. 2

Literatur

  1. Ando M, Yanagisawa N. Epidemiology, clinical characteristics, and management of chronic kidney disease in human immunodefciency virus-infected patients. World J Nephrol 2015;4:388–95

    Article  Google Scholar 

  2. Lucas GM, Ross MJ, Stock PG, et al. Clinical practice guideline for the management of chronic kidney disease in patients infected with HIV: 2014 update by the HIV Medicine Association of the Infectious Diseases Society of America. Clin Infect Dis 2014;59:e96–138

    Article  CAS  Google Scholar 

  3. Swanepoel CR, Atta MG, D’Agati VD, et al. Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2018;93:545–559

    Article  Google Scholar 

  4. Guaraldi G, Orlando G, Zona S, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis 2011;53:1120–6

    Article  Google Scholar 

  5. Szczech LA, Hoover DR, Feldman JG, et al. Association between renal disease and outcomes among HIV-infected women receiving or not receiving antiretroviral therapy. Clin Infect Dis 2004;39:1199–206

    Article  Google Scholar 

  6. Kooij KW, Vogt L, Wit F, et al. Higher Prevalence and Faster Progression of Chronic Kidney Disease in Human Immunodefciency Virus-Infected Middle-Aged Individuals Compared With Human Immunodefciency Virus-Uninfected Controls. J Infect Dis 2017;216:622–631

    Article  CAS  Google Scholar 

  7. Ryom L, Dilling Lundgren J, Reiss P, et al. Use of Contemporary Protease Inhibitors and Risk of Incident Chronic Kidney Disease in Persons With Human Immunodefciency Virus: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study. J Infect Dis 2019;220:1629–1634

    Article  CAS  Google Scholar 

  8. Gomez M, Seybold U, Roider J, Harter G and Bogner JR. A retrospective analysis of weight changes in HIV-positive patients switching from a tenofovir disoproxil fumarate (TDF)- to a tenofovir alafenamide fumarate (TAF)-containing treatment regimen in one German university hospital in 2015–2017. Infection 2019;47:95–102

    Article  CAS  Google Scholar 

  9. Sax PE, Erlandson KM, Lake JE, et al. Weight Gain Following Initiation of Antiretroviral Therapy: Risk Factors in Randomized Comparative Clinical Trials. Clin Infect Dis 2019

    Google Scholar 

  10. Deutsche AIDS-Gesellschaft. Deutsch-Österreichische Leitlinien zur antiretroviralen Therapie der HIV-1-Infektion. 2019; verfügbar unter https://daignet.de/site-content/hiv-leitlinien/leitlinien-1/deutsch-oesterreichische-leitlinien-zur-antiretroviralentherapie-der-hiv-1-infektion-1

  11. Seitz NN, Lochbuhler K, Atzendorf J, Rauschert C, Pfeifer-Gerschel T and Kraus L. Trends In Substance Use And Related Disorders. Dtsch Arztebl Int 2019;116:585–591

    PubMed  PubMed Central  Google Scholar 

  12. Brath H, Grabovac I, Schalk H, Degen O and Dorner TE. Prevalence and Correlates of Smoking and Readiness to Quit Smoking in People Living with HIV in Austria and Germany. PLoS One 2016;11:e0150553

    Article  Google Scholar 

  13. World Health Organization. Preventing and managing other comorbidities and chronic care for people living with HIV, verfügbar unter https://www.who.int/hiv/pub/guidelines/arv2013/coinfection/comorbdities/en/. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection, ISBN: 978 92 4 150572 7. 2012/03/15 ed, 2013

  14. Islam FM, Wu J, Jansson J and Wilson DP. Relative risk of cardiovascular disease among people living with HIV: a systematic review and meta-analysis. HIV Med 2012;13:453–68

    CAS  PubMed  Google Scholar 

  15. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013;3:S1–150

    Article  Google Scholar 

  16. European AIDS Clinical Society. Guidelines Version 10. 2019; verfügbar unter https://www.eacsociety.org/fles/2019_guidelines-10.0_fnal.pdf

  17. Gupta SK, Kitch D, Tierney C, et al. Markers of renal disease and function are associated with systemic infammation in HIV infection. HIV Med 2015;16:591–8

    Article  CAS  Google Scholar 

  18. Zeder AJ, Hilge R, Schrader S, Bogner JR and Seybold U. Medium-grade tubular proteinuria is common in HIV-positive patients and specifcally associated with exposure to tenofovir disoproxil fumarate. Infection 2016;44:641–649

    Article  CAS  Google Scholar 

  19. Schrader J, Zeder A, Hilge R, Bogner JR and Seybold U. MediumGrade Proteinuria is a Risk Factor for Incident Markers of Chronic Kidney Disease. HIV Med 2020, in press

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ulrich Seybold MSc.

Additional information

This article is part of a supplement not sponsored by the industry

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Seybold, U. Genügen ein Kreatininwert und ein Urinstix?. MMW - Fortschritte der Medizin 162 (Suppl 2), 28–32 (2020). https://doi.org/10.1007/s15006-020-0642-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s15006-020-0642-1

Keywords

Navigation