Skip to main content
Log in

Patient vor postoperativen Komplikationen schützen

Komorbiditäten gefährden die Wundheilung

Effects of comorbidities on wound healing

  • FORTBILDUNG . ÜBERSICHT
  • Published:
MMW - Fortschritte der Medizin Aims and scope

Die Wundheilung ist ein komplexer Vorgang. Sie wird von Komorbiditäten und einer Reihe weiterer Faktoren beeinflusst. Im Beitrag erfahren Sie, was Sie Ihren Patienten präoperativ raten können.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Kaye, K.S., et al., The effect of increasing age on the risk of surgical site infection. J Infect Dis, 2005. 191(7): p. 1056–62.

    Article  Google Scholar 

  2. Malone, D.L., et al., Surgical site infections: reanalysis of risk factors. J Surg Res, 2002. 103(1): p. 89–95.

    Article  Google Scholar 

  3. Golden, S.H., et al., Perioperative glycemic control and the risk of infectious complications in a cohort of adults with diabetes. Diabetes Care, 1999. 22(9): p. 1408–14.

    Article  CAS  Google Scholar 

  4. Korol, E., et al., A systematic review of risk factors associated with surgical site infections among surgical patients. PLoS One, 2013. 8(12): p. e83743.

    Article  Google Scholar 

  5. Kamboj, M., et al., Risk of Surgical Site Infection (SSI) following Colorectal Resection Is Higher in Patients With Disseminated Cancer: An NCCN Member Cohort Study. Infect Control Hosp Epidemiol, 2018. 39(5): p. 555–562.

    Article  Google Scholar 

  6. Rohde, J.M., et al., Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis. Jama, 2014. 311(13): p. 1317–26.

    Article  CAS  Google Scholar 

  7. Schiergens, T.S., et al., Impact of perioperative allogeneic red blood cell transfusion on recurrence and overall survival after resection of colorectal liver metastases. Dis Colon Rectum, 2015. 58(1): p. 74–82.

    Article  Google Scholar 

  8. Shander, A., et al., Patient blood management in Europe. Br J Anaesth, 2012. 109(1): p. 55–68.

    Article  CAS  Google Scholar 

  9. Hirao, M., et al., Overweight is a risk factor for surgical site infection following distal gastrectomy for gastric cancer. Gastric Cancer, 2013. 16(2): p. 239–44.

    Article  Google Scholar 

  10. Pierpont, Y.N., et al., Obesity and surgical wound healing: a current review. ISRN Obes, 2014. 2014: p. 638936.

    PubMed  PubMed Central  Google Scholar 

  11. Anderin, C., et al., Weight loss before bariatric surgery and postoperative complications: data from the Scandinavian Obesity Registry (SOReg). Ann Surg, 2015. 261(5): p. 909–13.

    Article  Google Scholar 

  12. WHO Guidelines Approved by the Guidelines Review Committee, in Global Guidelines for the Prevention of Surgical Site Infection. 2018, World Health Organization (c) World Health Organization 2018.: Geneva.

  13. Amri, R., et al., Risk Stratification for Surgical Site Infections in Colon Cancer. JAMA Surg, 2017. 152(7): p. 686–690.

    Article  Google Scholar 

  14. Goertz, O., et al., [Wound healing complications in smokers, non-smokers and after abstinence from smoking]. Chirurg, 2012. 83(7): p. 652–6.

    Article  CAS  Google Scholar 

  15. Sorensen, L.T., et al., Smoking as a risk factor for wound healing and infection in breast cancer surgery. Eur J Surg Oncol, 2002. 28(8): p. 815–20.

    Article  CAS  Google Scholar 

  16. Egholm, J.W., et al., Perioperative alcohol cessation intervention for postoperative complications. Cochrane Database Syst Rev, 2018. 11: p. Cd008343.

    PubMed  Google Scholar 

  17. Wang, A.S., E.J. Armstrong, and A.W. Armstrong, Corticosteroids and wound healing: clinical considerations in the perioperative period. Am J Surg, 2013. 206(3): p. 410–7.

    Article  CAS  Google Scholar 

  18. Johnson, B.K., et al., Patterns and associated risk of perioperative use of anti-tumor necrosis factor in patients with rheumatoid arthritis undergoing total knee replacement. J Rheumatol, 2013. 40(5): p. 617–23.

    Article  CAS  Google Scholar 

  19. Capocasale, E., et al., Surgical site and early urinary tract infections in 1000 kidney transplants with antimicrobial perioperative prophylaxis. Transplant Proc, 2014. 46(10): p. 3455–8.

    Article  CAS  Google Scholar 

  20. Ekberg, H., et al., Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med, 2007. 357(25): p. 2562–75.

    Article  CAS  Google Scholar 

  21. Preiss, J.C., et al., [Updated German clinical practice guideline on „Diagnosis and treatment of Crohn’s disease“ 2014]. Z Gastroenterol, 2014. 52(12): p. 1431–84.

    Article  CAS  Google Scholar 

  22. Kruger, K., et al., [Recommendations of the German Society for Rheumatology on the perioperative approach under therapy with DMARDs and biologicals in inflammatory rheumatic diseases]. Z Rheumatol, 2014. 73 (1): p. 77-84.

  23. Dixon, W.G., et al., The influence of systemic glucocorticoid therapy upon the risk of non-serious infection in older patients with rheumatoid arthritis: a nested case-control study. Ann Rheum Dis, 2011. 70(6): p. 956–60.

    Article  CAS  Google Scholar 

  24. Kumar, A., et al., Inflammatory bowel disease: perioperative pharmacological considerations. Mayo Clin Proc, 2011. 86(8): p. 748–57.

    Article  Google Scholar 

  25. Poruk, K.E., et al., A novel, validated risk score to predict surgical site infection after pancreaticoduodenectomy. HPB (Oxford), 2016. 18(11): p. 893–899.

    Article  Google Scholar 

  26. Prävention postoperativer Wundinfektionen. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2018. 61(4): p. 448-473.

  27. [Prevention of postoperative surgical wound infection: recommendations of the Hospital Hygiene and Infection Prevention Committee of the Robert Koch Institute]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2007. 50 (3): p. 377-93.

  28. Dumville, J.C., et al., Dressings for the prevention of surgical site infection. Cochrane Database Syst Rev, 2014(9): p. Cd003091.

  29. Bechstein, W.O., Towards Simpler and Reliable Wound Care. Dtsch Arztebl Int, 2018. 115(13): p. 211–212.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Martin Kurt Angele.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lampert, C., Bösch, F., Werner, J. et al. Komorbiditäten gefährden die Wundheilung. MMW - Fortschritte der Medizin 161, 54–59 (2019). https://doi.org/10.1007/s15006-019-1157-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s15006-019-1157-5

Keywords

Navigation