Leberzirrhose ist im Frühstadium oft schwierig zu diagnostizieren. Wichtige Hinweise kann die in neuen Ultraschallgeräten integrierte Lebersteifigkeitsmessung liefern. Eine kleine Einführung.
Literatur
Bamber J, Cosgrove D, Dietrich CF et al. EFSUMB guidelines and recommendations on the clinical use of ultrasound elastography. Part 1: Basic principles and technology. Ultraschall Med. 2013;34:169–84
Friedrich-Rust M, Poynard T, Castera L. Critical comparison of elastography methods to assess chronic liver disease. Nat Rev Gastroenterol Hepatol. 2016;13:402–11
Schellhaas B, Strobel D, Wildner D et al. Two-dimensional shear-wave elastography: a new method comparable to acoustic radiation force impulse imaging? Eur J Gastroenterol Hepatol. 2017;29:723–9
Dietrich C, Bamber J, Berzigotti A, et al. EFSUMB Guidelines and Recommendations on the Clinical Use of Liver Ultrasound Elastography, Update 2017 (Long Version) Ultraschall Med 2017, online 13. April; doi: 10.1055/s-0043-103952
Friedrich-Rust M, Nierhoff J, Lupsor M et al. Performance of Acoustic Radiation Force Impulse imaging for the staging of liver fibrosis: a pooled meta-analysis. J Viral Hepat. 2012;19:e212–9
Pfeifer L, Zopf S, Siebler J et al. Prospective Evaluation of Acoustic Radiation Force Impulse (ARFI) Elastography and High-Frequency B-Mode Ultrasound in Compensated Patients for the Diagnosis of Liver Fibrosis/Cirrhosis in Comparison to Mini-Laparoscopic Biopsy. Ultraschall Med. 2015;36:581–9
Nierhoff J, Chávez Ortiz AA, Herrmann E et al. The efficiency of acoustic radiation force impulse imaging for the staging of liver fibrosis: a meta-analysis. Eur Radiol. 2013;23:3040–53
Friedrich-Rust M, Wunder K, Kriener S et al. Liver fibrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography. Radiology. 2009;252:595–604
Vergniol J, Foucher J, Terrebonne E et al. Noninvasive tests for fibrosis and liver stiffness predict 5-year outcomes of patients with chronic hepatitis C. Gastroenterology. 2011;140:1970–9
de Lédinghen V, Vergniol J, Barthe C et al. Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus Aliment. Pharmacol Ther. 2013;37:979–88
Pfeifer L, Strobel D, Neurath MF, Wildner D. Liver stiffness assessed by acoustic radiation force impulse (ARFI) technology is considerably increased in patients with cholestasis. Ultraschall Med. 2014;35:364–7
Goertz RS, Egger C, Neurath MF, Strobel D. Impact of food intake, ultrasound transducer, breathing maneuvers and body position on acoustic radiation force impulse (ARFI) elastometry of the liver. Ultraschall Med. 2012;33:380–5
Millonig G, Friedrich S, Adolf S et al. Liver stiffness is directly influenced by central venous pressure. J Hepatol. 2010;52:206–10
Sagir A, Erhardt A, Schmitt M, Häussinger D. Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage. Hepatology. 2008;47:592–5
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Pfeifer, L., Strobel, D. Mit Ultraschall die Leberelastizität messen. MMW - Fortschritte der Medizin 159, 59–62 (2017). https://doi.org/10.1007/s15006-017-9852-6
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DOI: https://doi.org/10.1007/s15006-017-9852-6