Skip to main content
Log in

Nach Zeckenstich

Wann an eine Borreliose denken?

Lyme borreliosis after tick bite. When to consider the diagnosis Lyme borreliosis?

  • FORTBILDUNG . SCHWERPUNKT
  • Published:
MMW - Fortschritte der Medizin Aims and scope

Nicht nur in der Krautzone von Wald und Wiesen, sondern auch in unseren Parks und Gärten lebt die Zecke Ixodes ricinus, auch gemeiner Holzbock genannt. Im Verlauf ihrer Entwicklung zur adulten Zecke und vor der Eiablage saugt sie Blut und kann dabei Borrelien aufnehmen und/oder übertragen. Wie wird eine Borreliose diagnostiziert und wie behandelt?

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3

Literatur

  1. Fingerle, V., H. Bergmeister, G. Liegl, E. Vanek and B. Wilske (1994). „Prevalence of Borrelia burgdorferi sensu lato in Ixodes ricinus in Southern Germany.“ J Spiroch Tick Dis 1:41–45.

    Google Scholar 

  2. Wilking, H., V. Fingerle, C. Klier, M. Thamm and K. Stark (2015). Antibodies against Borrelia burgdorferi sensu lato among Adults, Germany, 2008-2011. Emerg Infect Dis 21(1): 107–110.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Strle, F., L. Lusa, E. Ruzic-Sabljic, V. Maraspin, S. Lotric Furlan, J. Cimperman, K. Ogrinc, T. Rojko, J. Videcnik Zorman and D. Stupica (2013). „Clinical characteristics associated with Borrelia burgdorferi sensu lato skin culture results in patients with erythema migrans.“ PLoS One 8(12): e82132.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Stanek, G., V. Fingerle, K. P. Hunfeld, B. Jaulhac, R. Kaiser, A. Krause, W. Kristoferitsch, S. O’Connell, K. Ornstein and F. Strle (2011). „Lyme borreliosis: clinical case definitions fordiagnosis and management in Europe.“ Clinical Microbiology and Infection 17(1): 69–79.

    Article  CAS  PubMed  Google Scholar 

  5. Hofmann, H. (2012). „Variabilität der kutanen Lyme-Borreliose.“ Der Hautarzt 63(5): 381–389.

    Article  CAS  Google Scholar 

  6. Eriksson, P., M. T. Schroder, K. Niiranen, A. Nevanlinna, J. Panelius and A. Ranki} (2013). „The many faces of solitary and multiple erythema migrans.“ Acta Derm Venereol 93(6): 693–700.

    Article  PubMed  Google Scholar 

  7. AWMF Leitlinie der Deutschen Gesellschaft für Dermatologie (DDG), S2k-Leitlinie „Kutane Lyme Borreliose“ AWMF Reg Nr. 013-044l http://www.awmf.org/uploads/tx.../013-044l_S2k_Kutane_Lyme_Borreliose_2016-05.pdf

  8. Ang, C. W., A. H. Brandenburg, N. D. van Burgel, H. A. Bijlmer, T. Herremans, F. Stelma, F. V. Lunel and A. P. van Dam (2015). „A Dutch nationwide evaluation of serological assays for detection of Borrelia antibodies in clinically well-defined patients.“ Diagn Microbiol Infect Dis 83(3): 222–228.

    Article  CAS  PubMed  Google Scholar 

  9. Berglund, J., R. Eitrem, K. Ornstein, A. Lindberg, A. Ringer, H. Elmrud, M. Carlsson, A. Runehagen, C. Svanborg and R. Norrby (1995). „An epidemiologic study of Lyme disease in southern Sweden.“ N Engl J Med 333(20): 1319–1327.

    Article  CAS  PubMed  Google Scholar 

  10. Maraspin, V., J. Cimperman, S. Lotric-Furlan, E. Ruzic-Sabljic, T. Jurca, R. N. Picken and F. Strle (2002). „Solitary borrelial lymphocytoma in adult patients.“ Wien Klin Wochenschr 114(13-14): 515–523.

    CAS  PubMed  Google Scholar 

  11. Arnez, M., D. Pleterski-Rigler, T. Luznik-Bufon, E. Ruzić-Sabljć and F. Strle (2002). „Children with multiple erythema migrans: are there any pre-treatment symptoms and/or signs suggestive for central nervous system involvement?“ Wiener klinische Wochenschrift 114(13-14): 524–529.

    PubMed  Google Scholar 

  12. Brettschneider, S., H. Bruckbauer, N. Klugbauer and H. Hofmann (1998). „Diagnostic value of PCR for detection of Borrelia burgdorferi in skin biopsy and urine samples from patients with skin borreliosis.“ J Clin Microbiol 36(9): 2658–2665.

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Lupi, E., C. Hatz and P. Schlagenhauf (2013). „The efficacy of repellents against Aedes, Anopheles, Culex and Ixodes spp. -a literature review.“ Travel Med Infect Dis 11 (6): 374–411.

    Article  PubMed  Google Scholar 

  14. Gern, L. (2009). „Life cycle of Borrelia burgdorferi sensu lato and transmission to humans.“ Curr Probl Dermatol 37: 18–30.

    Article  PubMed  Google Scholar 

  15. Nadelman, R. B., J. Nowakowski, D. Fish, R. C. Falco, K. Freeman, D. McKenna, P. Welch, R. Marcus, M. E. Aguero-Rosenfeld, D. T. Dennis and G. P. Wormser (2001). „Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite.“ N Engl J Med 345(2): 79–84.

    Article  CAS  PubMed  Google Scholar 

  16. Knauer, J., I. Krupka, C. Fueldner, J. Lehmann and R. K. Straubinger (2011). „Evaluation of the preventive capacities of a topically applied azithromycin formulation against Lyme borreliosis in a murine model.“ J Antimicrob Chemother 66 (12): 2814–2822.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Piesman, J., A. Hojgaard, A. J. Ullmann and M. C. Dolan (2014). „Efficacy of an experimental azithromycin cream for prophylaxis of tick - transmitted lyme disease spirochete infection in a murine model.“ Antimicrob Agents Chemother 58 (1): 348–351.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Schwammeis M, Kündig T, Huber G, et al Topical azithromycin for the prevention of Lyme borreliosis: a randomized, placebo-controlled. Phase 3 efficacy trial Lacet Infect Dise 2017, 17, 322–329

    Article  Google Scholar 

Weiterführende Literatur

  • Dehnert, M., V. Fingerle, C. Klier, T. Talaska, M. Schlaud, G. Krause, H. Wilking and G. Poggensee (2012). „Seropositivity of Lyme borreliosis and associated risk factors: a population based study in Children and Adolescents in Germany (KiGGS).“ PLoS One 7 (8): e41321.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • AWMF Leitlinie der Deutschen Gesellschaft für Neurologie (DGN) S1 Leitlinie „Neuroborreliose“ AWMF Reg. Nr. 030-071l

  • Arnez, M., D. Pleterski-Rigler, T. Luznik-Bufon, E. Ruzic-Sabljic and F. Strle (2003). „Solitary and multiple erythema migrans in children: comparison of demographic, clinical and laboratory findings.“ Infection 31(6): 404–409.

    CAS  PubMed  Google Scholar 

  • Arnez, M. and E. Ruzic-Sabljic (2011). „Borrelia burgdorferi sensu lato bacteremia in Slovenian children with solitary and multiple erythema migrans.“ Pediatr Infect Dis J 30(11):988–990.

    Article  PubMed  Google Scholar 

  • http://www.awmf.org/uploads/tx_szleitlinien/030-071l_S1_Neuroborreliose_2012.pdf

  • Shapiro E Wormser G Prophylaxis with topical azithromycin against Lyme borreliosis Lancet Infectious diseases 2017 17, 246–248

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Heidelore Hofmann.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hofmann, H. Wann an eine Borreliose denken?. MMW - Fortschritte der Medizin 159, 52–56 (2017). https://doi.org/10.1007/s15006-017-9850-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s15006-017-9850-8

Keywords

Navigation