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Welche Therapie empfiehlt die Leitlinie Divertikelkrankheit?

Diverticular disease

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MMW - Fortschritte der Medizin Aims and scope

Kolondivertikel gehören zu den häufigsten gastrointestinalen Befunden. Doch solange sie keine Symptome verursachen und es zu keinen Komplikationen kommt, haben sie keinen Krankheitswert. Die deutsche S2k-Leitlinie schlägt eine neue Klassifikation der Divertikelkrankheit in Typen statt Stadien vor. Daran richtet sich auch die Therapie aus.

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Literatur

  1. Delvaux M. Diverticular disease of the colon in Europe: epidemiology, impact on citizen health and prevention. Aliment Pharmacol Ther. 2003;18(Suppl 3):71–4.

    Article  PubMed  Google Scholar 

  2. Peery AF, Barrett PR, Park D, Rogers AJ, Galanko JA, Martin CF, Sandler RS. A high-fiber diet does not protect against asymptomatic diverticulosis. Gastroenterology 2012;142(2):266–72.

    Article  PubMed Central  PubMed  Google Scholar 

  3. Peery AF, Sandler RS, Ahnen DJ, Galanko JA, Holm AN, Shaukat A, Mott LA, Barry EL, Fried DA, Baron JA. Constipation and a low-fiber diet are not associated with diverticulosis. Clin Gastroenterol Hepatol. 2013;11(12):1622–7.

    Article  PubMed  Google Scholar 

  4. Shahedi K, Fuller G, Bolus R, Cohen E, Vu M, Shah R, Agarwal N, Kaneshiro M, Atia M, Sheen V, Kurzbard N, van Oijen MG, Yen L, Hodgkins P, Erder MH, Spiegel B. Long-term risk of acute diverticulitis among patients with incidental diverticulosis found during colonoscopy. Clin Gastroenterol Hepatol. 2013;11(12):1609–13.

    Article  PubMed  Google Scholar 

  5. Strate LL, Modi R, Cohen E, Spiegel BM. Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights. Am J Gastroenterol. 2012; 107(10): 1486–93.

    Article  PubMed  Google Scholar 

  6. Strate LL, Liu YL, Syngal S, Aldoori WH, Giovannucci EL. Nut, corn, and popcorn consumption and the incidence of diverticular disease. JAMA. 2008;300(8):907–14.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  7. Leifeld L, Germer CT, Böhm S, Dumoulin FL, Häuser W, Kreis M, Labenz J, Lembcke B, Post S, Reinshagen M, Ritz JP, Sauerbruch T, Wedel T, von Rahden B, Kruis W. S2k-Leitlinie Divertikelkrankheit/Divertikulitis Z Gastroenterol. 2014;52(7):663–710.

  8. Aldoori WH, Giovannucci EL, Rimm EB, Wing AL, Trichopoulos DV, Willett WC. A prospective study of diet and the risk of symptomatic diverticular disease in men. Am J Clin Nutr. 1994;60(5):757–64.

    CAS  PubMed  Google Scholar 

  9. Strate LL, Liu YL, Aldoori WH, Giovannucci EL. Physical activity decreases diverticular complications. Am J Gastroenterol 2009;104(5):1221–30.

    Article  PubMed Central  PubMed  Google Scholar 

  10. Chabok A, Påhlman L, Hjern F, Haapaniemi S, Smedh K; AVOD Study Group. Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br J Surg. 2012; 99(4): 532–9.

    Article  CAS  PubMed  Google Scholar 

  11. Daniels L et al. UEG J 2014, Abstract P0928.

  12. Kruis W, Meier E, Schumacher M, Mickisch O, Greinwald R, Mueller R; German SAG-20 Study Group. Randomised clinical trial: mesalazine (Salofalk granules) for uncomplicated diverticular disease of the colon - a placebo-controlled study. Aliment Pharmacol Ther. 2013;37(7):680–90

    Article  CAS  PubMed  Google Scholar 

  13. Bianchi M, Festa V, Moretti A, Ciaco A, Mangone M, Tornatore V, Dezi A, Luchetti R, De Pascalis B, Papi C, Koch M. Meta-analysis: long-term therapy with rifaximin in the management of uncomplicated diverticular disease. Aliment Pharmacol Ther. 2011;33(8):902–10.

    Article  CAS  PubMed  Google Scholar 

  14. Kruis W, Kardalinos V, Curtin A, Dorofeyev AE, Zakko SF, Wölkner J, MM Diez Alonso, Peeters H, and others Daily Mesalamine Fails to Prevent Recurrent Diverticulitis in a Large Placebo Controlled Multicenter Trial. Gastroenterology 2014;146(5);S–187.

    Google Scholar 

  15. Raskin JB, Kamm MA, Jamal MM, Márquez J, Melzer E, Schoen RE, SzalÓki T, Barrett K, Streck P. Mesalamine did not prevent recurrent diverticulitis in phase 3 controlled trials. Gastroenterology. 2014;147(4):793–802.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Manfred Gross.

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Gross, M. Welche Therapie empfiehlt die Leitlinie Divertikelkrankheit?. MMW - Fortschritte der Medizin 158, 48–52 (2016). https://doi.org/10.1007/s15006-016-7755-6

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  • DOI: https://doi.org/10.1007/s15006-016-7755-6

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