Skip to main content
Log in

Individuelle Nutzen-Risiko-Abwägung

Brauchen alle Diabetiker Aspirin und Statine?

  • FORTBILDUNG_SCHWERPUNKT
  • Published:
MMW - Fortschritte der Medizin Aims and scope

Die Prognose von Diabetikern hat sich in den letzten Jahrzehnten deutlich verbessert. Hierzu haben Präventionsmaßnahmen wie Lipidsenkung, Blutdruckeinstellung, Blutzuckeroptimierung und Thrombozytenaggregationshemmung entscheidend beigetragen. Dennoch sollten Sie im Einzelfall abwägen, ob Statine und/oder Aspirin indiziert sind.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Gregg EW, Li Y, Wang J, Burrows NR, Ali MK, Rolka D, et al. Changes in diabetes-related complications in the United States, 1990-2010. N Engl J Med. 2014;370:1514–23.

    Article  CAS  PubMed  Google Scholar 

  2. Mihaylova B, Emberson J, Blackwell L, Keech A, Simes J, Barnes EH, et al. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet. 2012;380:581–90.

    Article  CAS  PubMed  Google Scholar 

  3. Kearney PM, Blackwell L, Collins R, Keech A, Simes J, Peto R, et al. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet. 2008;371:117–25.

    Article  CAS  PubMed  Google Scholar 

  4. Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, Wiklund O, et al. ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J. 2011;32:1769–818.

    Article  PubMed  Google Scholar 

  5. Stone NJ, Robinson J, Lichtenstein AH, Merz CN, Blum CB, Eckel RH, et al. 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2013.

    Google Scholar 

  6. Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, Peto R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009;373:1849–60.

    Article  PubMed  Google Scholar 

  7. Belch J, MacCuish A, Campbell I, Cobbe S, Taylor R, Prescott R, et al. The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease. BMJ. 2008;337:a1840.

    Article  PubMed Central  PubMed  Google Scholar 

  8. Ogawa H, Nakayama M, Morimoto T, Uemura S, Kanauchi M, Doi N, et al. Low-dose aspirin for primary prevention of atherosclerotic events in patients with type 2 diabetes: a randomized controlled trial. JAMA. 2008;300:2134–41.

    Article  CAS  PubMed  Google Scholar 

  9. 8. Cardiovascular Disease and Risk Management. Diabetes Care. 2015;38:S49-S57.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Klaus G. Parhofer.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Parhofer, K.G. Brauchen alle Diabetiker Aspirin und Statine?. MMW - Fortschritte der Medizin 157, 43–45 (2015). https://doi.org/10.1007/s15006-015-3031-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s15006-015-3031-4

Keywords - Aspirin and statins for every diabetic?

Navigation