In Deutschland warten derzeit 11 000 Menschen auf eine Organtransplantation. Um diesen Engpass zu überbrücken, werden mittlerweile z. B. 30% der Nierentransplantationen als Lebendspende vorgenommen. Der Anteil der Leberlebendspenden stagniert dagegen seit mehreren Jahren. Der nachfolgende Beitrag beschreibt den Ablauf einer Leberlebendtransplantation, Schwierigkeiten, Risiken und den zukünftigen Stellenwert.
Literatur
Bismuth H, Houssin D: Reduced-sized orthotopic liver graft in hepatic transplantation in children. Surgery 1984, 95:367–70.
Broelsch CE, Emond JC, Thistlethwaite JR, Whitington PF, Zucker AR, Baker AL, Aran PF, Rouch DA, Lichtor JL: Liver transplantation, including the concept of reduced-size liver transplants in children. Annals of surgery 1988, 208:410–20.
Broelsch CE, Whitington PF, Emond JC, Heffron TG, Thistlethwaite JR, Stevens L, Piper J, Whitington SH, Lichtor JL: Liver transplantation in children from living related donors. Surgical techniques and results. Annals of surgery 1991, 214:428–37; discussion 37-9.
Guidance for Medical Evaluation of Potential Living Liver Donors http://optn.transplant.hrsa.gov/ContentDocuments/Guidance_MedicalEvaluationPotentialLivingLiverDonors.pdf. 2009.
Lee S, Hwang S, Park K, Lee Y, Choi D, Ahn C, Nah Y, Koh K, Han S, Park S, Min P: An adult-to-adult living donor liver transplant using dual left lobe grafts. Surgery 2001, 129:647–50.
Hwang S, Lee SG, Lee YJ, Sung KB, Park KM, Kim KH, Ahn CS, Moon DB, Hwang GS, Kim KM, Ha TY, Kim DS, Jung JP, Song GW: Lessons learned from 1,000 living donor liver transplantations in a single center: how to make living donations safe. Liver transplantation: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006, 12:920–7.
Florman S, Miller CM: Live donor liver transplantation. Liver transplantation: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006, 12:499–510.
Guba M, Adcock L, MacLeod C, Cattral M, Greig P, Levy G, Grant D, Khalili K, McGilvray ID: Intraoperative ‚no go ‘donor hepatectomies in living donor liver transplantation. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010, 10:612–8.
Gali B, Rosen CB, Plevak DJ: Living donor liver transplantation: selection, perioperative care, and outcome. Journal of intensive care medicine 2012, 27:71–8.
Akamatsu N, Sugawara Y, Hashimoto D: Biliary reconstruction, its complications and management of biliary complications after adult liver transplantation: a systematic review of the incidence, risk factors and outcome. Transplant international: official journal of the European Society for Organ Transplantation 2011, 24:379–92.
Shah SA, Levy GA, Greig PD, Smith R, McGilvray ID, Lilly LB, Girgrah N, Cattral MS, Grant DR: Reduced mortality with right-lobe living donor compared to deceased-donor liver transplantation when analyzed from the time of listing. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007, 7:998–1002.
Lee SG, Hwang S, Kim KH, Ahn CS, Moon DB, Ha TY, Song KW, Chung DH: Toward 300 liver transplants a year. Surgery today 2009, 39:367–73.
Miller C, Smith ML, Fujiki M, Uso TD, Quintini C: Preparing for the inevitable: the death of a living liver donor. Liver transplantation: official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2013, 19:656–60.
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Andrassy, J., Werner, J. & Guba, M. Leberlebendspende: Chancen und Risiken. MMW - Fortschritte der Medizin 156, 54–57 (2014). https://doi.org/10.1007/s15006-014-3270-9
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DOI: https://doi.org/10.1007/s15006-014-3270-9